Versatile surface engineering of porous nanomaterials with bioinspired polyphenol coatings for targeted and controlled drug delivery

Nanoscale ◽  
2016 ◽  
Vol 8 (16) ◽  
pp. 8600-8606 ◽  
Author(s):  
Juan Li ◽  
Shuxian Wu ◽  
Cuichen Wu ◽  
Liping Qiu ◽  
Guizhi Zhu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Surface Engineering ◽  
Controlled Drug Delivery ◽  
Porous Nanomaterials

Porous silicon nanomaterials: recent advances in surface engineering for controlled drug-delivery applications

Nanomedicine ◽  
2019 ◽  
Vol 14 (24) ◽  
pp. 3213-3230 ◽  
Author(s):  
De-Xiang Zhang ◽  
Lars Esser ◽  
Roshan B Vasani ◽  
Helmut Thissen ◽  
Nicolas H Voelcker
Keyword(s):  
Drug Delivery ◽  
Surface Modification ◽  
Porous Silicon ◽  
Surface Engineering ◽  
Controlled Drug Delivery ◽  
Current Status ◽  
Polymer Grafting ◽  
Recent Advances ◽  
Drug Delivery Applications

Porous silicon (pSi) nanomaterials are increasingly attractive for biomedical applications due to their promising properties such as simple and feasible fabrication procedures, tunable morphology, versatile surface modification routes, biocompatibility and biodegradability. This review focuses on recent advances in surface modification of pSi for controlled drug delivery applications. A range of functionalization strategies and fabrication methods for pSi-polymer hybrids are summarized. Surface engineering solutions such as stimuli-responsive polymer grafting, stealth coatings and active targeting modifications are highlighted as examples to demonstrate what can be achieved. Finally, the current status of engineered pSi nanomaterials for in vivo applications is reviewed and future prospects and challenges in drug-delivery applications are discussed.

Atherosclerosis and Nanomedicine Potential: Current Advances and Future Opportunities

2020 ◽  
Vol 27 (21) ◽  
pp. 3534-3554 ◽  
Author(s):  
Fan Jiang ◽  
Yunqi Zhu ◽  
Changyang Gong ◽  
Xin Wei
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Controlled Drug Delivery ◽  
Vascular Wall ◽  
Arterial Disease ◽  
Diagnosis And Treatment ◽  
Antiinflammatory Therapy ◽  
Limited Efficacy ◽  
Conventional Drug ◽  
Diagnostic Modalities

Atherosclerosis is the leading inducement of cardiovascular diseases, which ranks the first cause of global deaths. It is an arterial disease associated with dyslipidemia and changes in the composition of the vascular wall. Besides invasive surgical strategy, the current conservative clinical treatment for atherosclerosis falls into two categories, lipid regulating-based therapy and antiinflammatory therapy. However, the existing strategies based on conventional drug delivery systems have shown limited efficacy against disease development and plenty of side effects. Nanomedicine has great potential in the development of targeted therapy, controlled drug delivery and release, the design of novel specific drugs and diagnostic modalities, and biocompatible scaffolds with multifunctional characteristics, which has led to an evolution in the diagnosis and treatment of atherosclerosis. This paper will focus on the latest nanomedicine strategies for atherosclerosis diagnosis and treatment as well as discussing the potential therapeutic targets during atherosclerosis progress, which could form the basis of development of novel nanoplatform against atherosclerosis.

Co-polymerized Gellan Gum: A Carrier for Controlled Drug Delivery

2016 ◽  
Vol 5 (3) ◽  
pp. 151-162
Author(s):  
Ranjeet Pareek ◽  
Shakuntla Verma ◽  
Viney Lather ◽  
Deepti Pandita
Keyword(s):  
Drug Delivery ◽  
Controlled Drug Delivery ◽  
Gellan Gum

scholarly journals Nanotechnology: from In Vivo Imaging System to Controlled Drug Delivery

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Maria Mir ◽  
Saba Ishtiaq ◽  
Samreen Rabia ◽  
Maryam Khatoon ◽  
Ahmad Zeb ◽  
...  
Keyword(s):  
Drug Delivery ◽  
In Vivo Imaging ◽  
Imaging System ◽  
Controlled Drug Delivery ◽  
In Vivo Imaging System
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