scholarly journals (Indolylalkyl)piperidine carbamates as inhibitors of fatty acid amide hydrolase (FAAH)

MedChemComm ◽  
2017 ◽  
Vol 8 (3) ◽  
pp. 616-620 ◽  
Author(s):  
Helmut Dahlhaus ◽  
Walburga Hanekamp ◽  
Matthias Lehr
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Amide Hydrolase ◽  
Acid Amide ◽  
Metabolic Stability ◽  
Inhibitory Potency ◽  
Amide Hydrolase ◽  
Fatty Acid Amide

Studies on FAAH inhibitory potency and metabolic stability of indolyl-substituted alkyl- and alkylpiperidine carbamates are described.

ω-Imidazolyl- and ω-Tetrazolylalkylcarbamates as Inhibitors of Fatty Acid Amide Hydrolase: Biological Activity and in vitro Metabolic Stability

ChemMedChem ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 429-443 ◽  
Author(s):  
Tobias Terwege ◽  
Walburga Hanekamp ◽  
David Garzinsky ◽  
Simone König ◽  
Oliver Koch ◽  
...  
Keyword(s):  
Biological Activity ◽  
Fatty Acid ◽  
Fatty Acid Amide Hydrolase ◽  
Acid Amide ◽  
Metabolic Stability ◽  
Amide Hydrolase ◽  
Fatty Acid Amide

ω-Heteroarylalkylcarbamates as inhibitors of fatty acid amide hydrolase (FAAH)

MedChemComm ◽  
2014 ◽  
Vol 5 (7) ◽  
pp. 932-936 ◽  
Author(s):  
Tobias Terwege ◽  
Helmut Dahlhaus ◽  
Walburga Hanekamp ◽  
Matthias Lehr
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Amide Hydrolase ◽  
Acid Amide ◽  
Inhibitory Potency ◽  
Amide Hydrolase ◽  
Fatty Acid Amide

A series of heteroaryl-substituted alkylcarbamates have been synthesized and evaluated for their inhibitory potency against fatty acid amide hydrolase (FAAH).

Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets

2007 ◽  
Vol 52 (4) ◽  
pp. 1095-1105 ◽  
Author(s):  
Di Zhang ◽  
Anita Saraf ◽  
Teodozyi Kolasa ◽  
Pramila Bhatia ◽  
Guo Zhu Zheng ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Amide Hydrolase ◽  
Acid Amide ◽  
Amide Hydrolase ◽  
Fatty Acid Amide
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