scholarly journals Chitosan nanoparticles for nitric oxide delivery in human skin

MedChemComm ◽  
2017 ◽  
Vol 8 (4) ◽  
pp. 713-719 ◽  
Author(s):  
M. T. Pelegrino ◽  
R. B. Weller ◽  
X. Chen ◽  
J. S. Bernardes ◽  
A. B. Seabra
Keyword(s):  
Nitric Oxide ◽  
Human Skin ◽  
Transdermal Delivery ◽  
Chitosan Nanoparticles ◽  
Therapeutic Agents ◽  
Delivery Systems ◽  
Systemic Administration ◽  
Nitric Oxide Delivery

The use of nanoparticle-based transdermal delivery systems is a promising approach to efficiently carry and deliver therapeutic agents for dermal and systemic administration.

Development of a Sustained-release System for Nitric Oxide Delivery using Alginate/Chitosan Nanoparticles

2013 ◽  
Vol 9 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Priscyla D. Marcato ◽  
Leonardo F. Adami ◽  
Raquel de Melo Barbosa ◽  
Patricia S. Melo ◽  
Iasmin R. Ferreira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sustained Release ◽  
Chitosan Nanoparticles ◽  
Release System ◽  
Nitric Oxide Delivery

Development of a Sustained-release System for Nitric Oxide Delivery using Alginate/Chitosan Nanoparticles

2013 ◽  
Vol 9 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Priscyla D. Marcato ◽  
Leonardo F. Adami ◽  
Raquel de Melo Barbosa ◽  
Patricia S. Melo ◽  
Iasmin R. Ferreira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sustained Release ◽  
Chitosan Nanoparticles ◽  
Release System ◽  
Nitric Oxide Delivery

Inhaled Nitric Oxide Delivery Systems 

1997 ◽  
Vol 87 (6) ◽  
pp. 1591-1592 ◽  
Author(s):  
Eric Troncy ◽  
Martin Francoeur ◽  
Gilbert Blaise
Keyword(s):  
Nitric Oxide ◽  
Delivery Systems ◽  
Inhaled Nitric Oxide ◽  
Nitric Oxide Delivery

Inhaled Nitric Oxide Delivery Systems for Mechanically Ventilated and Nonintubated Patients: A Review

2021 ◽  
Vol 66 (6) ◽  
pp. 1021-1028
Author(s):  
Stefano Gianni ◽  
Ryan W Carroll ◽  
Robert M Kacmarek, ◽  
Lorenzo Berra
Keyword(s):  
Nitric Oxide ◽  
Delivery Systems ◽  
Inhaled Nitric Oxide ◽  
Mechanically Ventilated ◽  
Nitric Oxide Delivery

scholarly journals Design of nitric oxide delivery systems

1995 ◽  
Vol 75 (2) ◽  
pp. 253
Author(s):  
A V Powroznyk ◽  
R D Latimer ◽  
A Oduro
Keyword(s):  
Nitric Oxide ◽  
Delivery Systems ◽  
Nitric Oxide Delivery

Molecular Design and Medicinal Applications of Nano-Nitric Oxide Delivery Systems

2018 ◽  
Vol 25 (12) ◽  
pp. 1420-1432 ◽  
Author(s):  
Kim Truc Nguyen ◽  
Zhuoran Wu ◽  
Tiantian Huang ◽  
Chor Yong Tay
Keyword(s):  
Nitric Oxide ◽  
Biomedical Applications ◽  
Molecular Design ◽  
State Of The Art ◽  
Delivery Systems ◽  
Biological Functions ◽  
Design And Synthesis ◽  
Current State ◽  
Anti Cancer ◽  
Nitric Oxide Delivery

Background: Nitric oxide (NO) plays important regulatory roles in a plethora of biological functions and thus holds tremendous potential to be exploited for clinical uses. However, the chemistries in the molecular design of nano-nitric oxide delivery systems is currently lacking. Objective: The overarching aim of this review is to provide the readers with the fundamentals that relate to the design of NO release molecules (NORMs), loading and releasing mechanism, as well as delivery of NORMs for nanotherapeutics. Methods: We conducted a thorough literature search on the design and synthesis of NORMs, as well as the current state-of-the-art NO compatible delivery platforms to address various clinical needs. Results: N-diazeniumdiolate and S-nitrosothiol based NO molecules are among the most widely used NORMs for anti-cancer and anti-microbial applications. The innovative integration of these NORMs with cytocompatible organic and inorganic nanocarriers enabled controlled spatiotemporal delivery and release of NO at the targeted diseased sites. Conclusion: We have provided a comprehensive summary of the fundamental chemistries underpinning the molecular design of the NORMs and critically assessed the recent advancements of nano-NO delivery systems for advanced biomedical applications.

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