scholarly journals Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(iii) complex in human cancer cell lines

MedChemComm ◽  
2016 ◽  
Vol 7 (8) ◽  
pp. 1604-1616 ◽  
Author(s):  
Nenad R. Filipović ◽  
Snežana Bjelogrlić ◽  
Gustavo Portalone ◽  
Sveva Pelliccia ◽  
Romano Silvestri ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Plasmid Dna ◽  
Human Cancer ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Differentiation Induction

The ligand initiated reprogramming of cancer stem cells phenotype in AsPC-1 cells. The complex digested plasmid DNA which might be the cause of its cytotoxic activity.

Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells?

2009 ◽  
Vol 1795 (2) ◽  
pp. 92-103 ◽  
Author(s):  
W.C.G. van Staveren ◽  
D.Y. Weiss Solís ◽  
A. Hébrant ◽  
V. Detours ◽  
J.E. Dumont ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Experimental Models ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

Cytotoxic activity of sesquiterpene lactones from Inula britannica on human cancer cell lines

2013 ◽  
Vol 6 (2) ◽  
pp. 246-252 ◽  
Author(s):  
Justin T. Fischedick ◽  
Milica Pesic ◽  
Ana Podolski-Renic ◽  
Jasna Bankovic ◽  
Ric C.H. de Vos ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Sesquiterpene Lactones ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Inula Britannica

scholarly journals Alkaloids From Zanthoxylum nitidum and Their Cytotoxic Activity

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1984413
Author(s):  
Thi Hong Van Nguyen ◽  
Thi Tuyen Tran ◽  
Thi Inh Cam ◽  
Minh Quan Pham ◽  
Quoc Long Pham ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Spectroscopy Data ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Zanthoxylum Nitidum ◽  
Mcf 7

Zanthoxylum nitidum (Roxb.) DC (Rutaceae) is a traditional medicine used for the treatment of various diseases like toothache, gingivitis, fever, colic vomiting, diarrhea, and cholera. Three new alkaloids, zanthocadinanine C (1), 7-methoxy-8-demethoxynitidine (2), and zanthonitiside I (3) were isolated from the stems and twigs of Z. nitidum. Their structures were determined on the basis of extensive spectroscopic, including 1-dimensional and 2-dimensional nuclear magnetic resonance and mass spectroscopy data. Compounds 1–3 were evaluated for cytotoxic activity against 5 human cancer cell lines, KB, MCF-7, LNCaP, HepG-2, and LU-1. Compound 2 showed significant cytotoxic activity against all tested human cancer cell lines with IC50 values ranging from 10.3 to 12.6 µM.

Synthesis, crystal structure, and cytotoxic activity of novel cyclic systems in [1,2,4]thiadiazolo[2,3-a]pyridine benzamide derivatives and their copper(ii) complexes

2014 ◽  
Vol 43 (21) ◽  
pp. 7945-7957 ◽  
Author(s):  
Forogh Adhami ◽  
Maliheh Safavi ◽  
Maryam Ehsani ◽  
Sussan K. Ardestani ◽  
Franziska Emmerling ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Planar Structure ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Square Planar ◽  
Benzamide Derivatives

Novel Cu2+complexes with a square planar structure synthesized from benzamide derivatives showed cytotoxic activity against different human cancer cell lines.

Cytostatic and cytotoxic activity of synthetic genistein glycosides against human cancer cell lines

2004 ◽  
Vol 203 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Krzysztof Polkowski ◽  
Joanna Popiołkiewicz ◽  
Piotr Krzeczyński ◽  
Jan Ramza ◽  
Wiesław Pucko ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

scholarly journals SYNTHESIS AND CYTOTOXIC ACTIVITY EVALUATION OF NOVEL DERIVATIVES OF MURRAYAFOLINE A

2018 ◽  
Vol 54 (2C) ◽  
pp. 502
Author(s):  
Le Duc Anh
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Hep G2 ◽  
Human Cancer Cell Lines ◽  
Activity Evaluation ◽  
Derivatives Of

Two new conjugates of murrayafoline A with zerumbone and artemisinin 3, 11 wereprepared by N-alkylation, in which, compound 3 was synthesized from two consecutive Nalkylationreactions. Their cytotoxicity was evaluated on four human cancer cell lines Hep-G2,LU, RD and Fl. The result showed that both compounds exhibited no activity against the testedcell lines.

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