Iron isotopic analysis of finger-prick and venous blood by multi-collector inductively coupled plasma-mass spectrometry after volumetric absorptive microsampling

2017 ◽  
Vol 32 (2) ◽  
pp. 314-321 ◽  
Author(s):  
Yulia Anoshkina ◽  
Marta Costas-Rodríguez ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
High Precision ◽  
Whole Blood ◽  
Inductively Coupled Plasma ◽  
Venous Blood ◽  
Isotopic Analysis ◽  
Inductively Coupled ◽  
Finger Prick ◽  
Plasma Mass Spectrometry ◽  
Volumetric Absorptive Microsampling

The use of VAMS – volumetric absorptive microsampling – of finger-prick blood was evaluated in the context of high-precision isotopic analysis of whole blood Fe by multi-collector inductively coupled plasma-mass spectrometry.

A simple method for high-precision isotopic analysis of chlorine via pneumatic nebulization multi-collector inductively coupled plasma-mass spectrometry

2016 ◽  
Vol 31 (2) ◽  
pp. 537-542 ◽  
Author(s):  
Jefferson S. de Gois ◽  
Marta Costas-Rodríguez ◽  
Paul Vallelonga ◽  
Daniel L. G. Borges ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
High Precision ◽  
Inductively Coupled Plasma ◽  
Isotopic Analysis ◽  
Spectral Interference ◽  
Simple Method ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Low Sensitivity

Despite the occurrence of spectral interference, memory effects and the characteristic low sensitivity, isotopic analysis of Cl in seawater can be successfully performed using PN-MC-ICP-MS.

scholarly journals Isotope analysis of highly enriched “silicon-28” by high-resolution inductively coupled plasma mass spectrometry using an internal standard

2021 ◽  
Vol 25 (2) ◽  
pp. 98-109
Author(s):  
P. A. Otopkova ◽  
◽  
A. M. Potapov ◽  
A. I. Suchkov ◽  
A. D. Bulanov ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Matrix Element ◽  
High Resolution ◽  
Inductively Coupled Plasma ◽  
Internal Standard ◽  
Isotopic Analysis ◽  
Random Component ◽  
Inductively Coupled ◽  
The Matrix ◽  
Plasma Mass Spectrometry

In order to study the isotopic effects in semiconductor materials, single crystals of high chemical and isotopic purity are required. The reliability of the obtained data on the magnitude and the direction of isotopic shifts depends on the accuracy of determining the concentration of all stable isotopes. In the isotopic analysis of enriched “silicon-28” with a high degree of enrichment (> 99.99%), it is necessary to determine the impurities of 29Si and 30Si isotopes at the level of 10-3 ¸ 10-5 at. %. At this concentration level, these isotopes can be considered as impurities. It is difficult to achieve high measurement accuracy with simultaneous registration of the main and “impurity” isotopes in such a wide range of concentrations. The registration of analytical signals of silicon isotopes must be carried out in the solutions with different matrix concentrations. The use of the solutions with the high concentration of the matrix element requires the introduction of corrections for matrix noise and the drift of the instrument sensitivity during the measurement. It is possible to reduce the influence of the irreversible non-spectral interference and sensitivity drift by using the method of internal standardization. The inconsistency of the literature data on the selection criteria for the internal standard required studying the behavior of the signals of the “candidates for the internal standard” for the ELEMENT 2 single-collector high-resolution inductively coupled plasma mass spectrometer on the matrix element concentration and the nature of the solvent, as well as on the solution nebulizing time. Accounting for the irreversible non-spectral matrix noise and instrumental drift in isotopic analysis of enriched “silicon-28” and initial 28SiF4 by inductively coupled plasma mass spectrometry had allowed us to reduce by 3-5 times the random component and by more than an order of magnitude the systematic component of the measurement error in comparison with the external standard method. This made it possible to carry out, with sufficient accuracy, the operational control of the isotopic composition of enriched “silicon-28”, both in the form of silicon tetrafluoride and polycrystalline silicon obtained from it, using a single serial device in the range of isotopic concentrations 0.0001–99.999%.

Direct measurement of Fe isotope compositions in iron-dominate minerals without column chromatography using MC-ICP-MS

2022 ◽  
Author(s):  
Kaiyun Chen ◽  
Zhian Bao ◽  
Honglin Yuan ◽  
Nan Lv
Keyword(s):  
Mass Spectrometry ◽  
Direct Measurement ◽  
High Precision ◽  
Column Chromatography ◽  
Inductively Coupled Plasma ◽  
Practical Method ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Isotope Determination

This study presents a practical method for high-precision Fe isotope determination without column chromatography purification for iron-dominated mineral samples using multi-collector inductively coupled plasma-mass spectrometry (MC-ICP-MS). A series of comparable...

scholarly journals Selenium and other mineral concentrations in feed and sheep's blood in Kosovo

2017 ◽  
Vol 1 (1) ◽  
pp. 97-107 ◽  
Author(s):  
A. Ademi ◽  
A. Bernhoft ◽  
E. Govasmark ◽  
H. Bytyqi ◽  
T. Sivertsen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Whole Blood ◽  
Inductively Coupled Plasma ◽  
Blood Samples ◽  
Sheep Blood ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry ◽  
Toxic Minerals ◽  
Mineral Concentrations ◽  
Feed Samples

Abstract The aim of this study was to assess the concentration of Se and other minerals in sheep and the supplied feed. Four macrominerals (Ca, P, Mg, and S), 7 microminerals (Se, Fe, Zn, Cu, Mn, Co, and Mo), and 2 toxic minerals (Cd and Pb) were analyzed in 69 feed and 292 sheep blood samples from 30 farms in different regions of Kosovo. The samples were analyzed using inductively coupled plasma mass spectrometry, and mineral concentrations in whole blood were measured to assess their status in animals. Concentrations of the different minerals in feed were found in the following ranges: 1.9 to 9.5 g Ca/kg DM, 0.8 to 3.2 g P/kg DM, 0.8 to 3.2 g Mg/kg DM, 1.0 to 2.8 g S/kg DM, 6 to 82 µg Se/kg DM, 33 to 970 mg Fe/kg DM, 15 to 42 mg Zn/ kg DM, 2.6 to 7.5 mg Cu/kg DM, 26 to 250 mg Mn/kg DM, 0.04 to 0.88 mg Co/kg DM, 0.05 to 0.86 mg Mo/ kg DM, 0.07 to 2.02 mg Pb/kg DM, and 0.02 to 0.19 mg Cd/kg DM. Concentrations of the microminerals analyzed in whole blood were found in the following ranges: 15 to 360 µg Se/L, 190 to 500 mg Fe/L, 1.4 to 3.8 mg Zn/L, 0.3 to 2.6 mg Cu/L, 6 to 243 µg Mn/L, 0.1 to 19.6 µg Co/L, and 1.8 to 66.0 µg Pb/L. Among all minerals, the largest deficiency was found for Se both in feed and sheep blood, with 82% of feed samples and 83% blood samples being inadequate, and its supplementation is necessary. Selenium-supplemented sheep had significantly higher Se concentration in blood than non-supplemented sheep (P < 0.01). In addition, other macro- and microminerals in feed such as P, S, Cu, and Co were at inadequate concentrations at some of the farms, and supplementation may also be needed for these minerals.

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