Catalyst-free synthesis of fused 1,2,3-triazole and isoindoline derivatives via an intramolecular azide–alkene cascade reaction

2017 ◽  
Vol 19 (3) ◽  
pp. 656-659 ◽  
Author(s):  
Yu-Yang Xie ◽  
Ying-Chun Wang ◽  
Yan He ◽  
Da-Chao Hu ◽  
Heng-Shan Wang ◽  
...  

A simple and efficient methodology has been developed for the regioselective synthesis of fused 1,2,3-triazole and isoindoline derivatives under catalyst free conditions.

ChemInform ◽  
2015 ◽  
Vol 46 (41) ◽  
pp. no-no
Author(s):  
Xue-Bing Chen ◽  
Sheng-Jiao Yan ◽  
An Su ◽  
Wei Liu ◽  
Jun Lin

Tetrahedron ◽  
2015 ◽  
Vol 71 (29) ◽  
pp. 4745-4751 ◽  
Author(s):  
Xue-Bing Chen ◽  
Sheng-Jiao Yan ◽  
An Su ◽  
Wei Liu ◽  
Jun Lin

2019 ◽  
Vol 57 (1) ◽  
pp. 469-476 ◽  
Author(s):  
Sakkani Nagaraju ◽  
Kota Sathish ◽  
Neeli Satyanarayana ◽  
Banoth Paplal ◽  
Dhurke Kashinath

2019 ◽  
Vol 56 (11) ◽  
pp. 3055-3064 ◽  
Author(s):  
Kalawati Meena ◽  
Mohit Saroha ◽  
Ishani Khurana ◽  
Amita Malik ◽  
Pramod K. Rai ◽  
...  

ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Xian Feng ◽  
Jian-Jun Wang ◽  
Juan-Juan Zhang ◽  
Cheng-Pao Cao ◽  
Zhi-Bin Huang ◽  
...  

2019 ◽  
Vol 17 (35) ◽  
pp. 8153-8165 ◽  
Author(s):  
Jitendra Gour ◽  
Srikanth Gatadi ◽  
Ravikumar Akunuri ◽  
Madhavi Venkata Yaddanapudi ◽  
Mushtaq Ahmad Nengroo ◽  
...  

A general and catalyst-free access to the fused polycyclic N-heterocycles via an intramolecular azide–alkene cascade reaction under mild reaction conditions has been developed.


Synthesis ◽  
2020 ◽  
Vol 52 (23) ◽  
pp. 3604-3621 ◽  
Author(s):  
Vitaly A. Osyanin ◽  
Dmitry V. Osipov ◽  
Irina V. Melnikova ◽  
Kirill S. Korzhenko ◽  
Irina A. Semenova ◽  
...  

A new strategy to 2-aminochromanes through catalyst-free cascade reaction of 3-trifluoroacetyl-4H-chromenes and 4H-chromene-3-carbaldehydes with cyclic secondary amines is presented. The reaction proceeds through subsequent 1,4- and 1,2-additions of amine, bimolecular elimination of trifluoroacetamide or formamide, and 6-exo-trig cyclization. The latter stage is a very rare example of addition of phenols to enamines. The obtained semicyclic N,O-acetals were applied as useful precursors for the synthesis of other chromanes.


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