1H-NMR based metabolomics study for the detection of the human urine metabolic profile effects of Origanum dictamnus tea ingestion

2016 ◽  
Vol 7 (9) ◽  
pp. 4104-4115 ◽  
Author(s):  
Panteleimon G. Takis ◽  
Mariam-Eleni Oraiopoulou ◽  
Constantinos Konidaris ◽  
Anastassios N. Troganis
Keyword(s):  
1H Nmr ◽  
Human Urine ◽  
Metabolic Profile ◽  
Metabolomics Study ◽  
Urine Metabolome

NMR based metabolomics clarify theOriganum dictamnustea effect upon the human urine metabolome.

scholarly journals Metabolic Profiling and Untargeted 1H-NMR-Based Metabolomics Study of Different Iranian Pomegranate (Punica granatum) Ecotypes

Planta Medica ◽  
2019 ◽  
Vol 86 (03) ◽  
pp. 212-219 ◽  
Author(s):  
Maede Hasanpour ◽  
Satar Saberi ◽  
Mehrdad Iranshahi
Keyword(s):  
1H Nmr ◽  
Metabolic Profiling ◽  
Metabolic Profile ◽  
Punica Granatum ◽  
2D Nmr ◽  
2D Nmr Spectroscopy ◽  
Ecotypic Variation ◽  
Data Analyses ◽  
The World ◽  
Metabolomics Study

AbstractPomegranate (Punica granatum) is an ancient fruit that is widely consumed as fresh fruit and juice. The aim of the present study was to compare the metabolic profile of pomegranate ecotypes from different geographical origins of Iran, the largest producer of pomegranates in the world. 1H-NMR and 2D NMR spectroscopy were applied to investigate the ecotypic variation. Multivariate data analyses were used to identify overall metabolic differences. Mazandaran pomegranate samples were found to be different from the other ecotypes, having a high content of citric and succinic acids. Bajestan, Ferdows, and Yazd pomegranates contained comparatively higher amounts of anthocyanins and ellagic acid derivatives than other pomegranate ecotypes. The distribution of metabolites among different ecotypes of pomegranate is discussed on the basis of these findings.

scholarly journals 1H-NMR Profiling Shows as Specific Constituents Strongly Affect the International EVOO Blends Characteristics: The Case of the Italian Oil

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2233
Author(s):  
Francesca Calò ◽  
Chiara Roberta Girelli ◽  
Federica Angilè ◽  
Laura Del Coco ◽  
Lucia Mazzi ◽  
...  
Keyword(s):  
1H Nmr ◽  
Metabolic Profile ◽  
1H Nmr Spectroscopy ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Minor Components ◽  
Multivariate Statistical ◽  
Olive Oils ◽  
The World ◽  
Plateau Level

Considering the growing number of extra virgin olive oil (EVOO) producers in the world, knowing the influence of olive oils with different geographical origins on the characteristics of the final blend becomes an interesting goal. The present work is focused on commercial organic EVOO blends obtained by mixing multiple oils from different geographical origins. These blends have been studied by 1H-NMR spectroscopy supported by multivariate statistical analysis. Specific characteristics of commercial organic EVOO blends originated by mixing oils from Italy, Tunisia, Portugal, Spain, and Greece were found to be associated with the increasing content of the Italian component. A linear progression of the metabolic profile defined characteristics for the analysed samples—up to a plateau level—was found in relation to the content of the main constituent of the Italian oil, the monocultivar Coratina. The Italian constituent percentage appears to be correlated with the fatty acids (oleic) and the polyphenols (tyrosol, hydroxytyrosol, and derivatives) content as major and minor components respectively. These results, which highlight important economic aspects, also show the utility of 1H-NMR associated with chemometric analysis as a powerful tool in this field. Mixing oils of different national origins, to obtain blends with specific characteristics, could be profitably controlled by this methodology.

scholarly journals 1H NMR-based metabolomics study on the physiological variations during the rat pregnancy process

2016 ◽  
Vol 423 ◽  
pp. 40-50 ◽  
Author(s):  
Guiping Shen ◽  
Zhishui Li ◽  
Yan Zhang ◽  
Huifeng Wu ◽  
Jianghua Feng
Keyword(s):  
1H Nmr ◽  
Metabolomics Study ◽  
Physiological Variations

1H-NMR Based Metabolomics Study of the Intestinal Epithelial Cell (IEC-6) Under the Oxidative Stress

2010 ◽  
Vol 158 (2) ◽  
pp. 256 ◽  
Author(s):  
K. Nakata ◽  
N. Sato ◽  
T. Asakura ◽  
K. Hirakawa ◽  
R. Zhu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Epithelial Cell ◽  
1H Nmr ◽  
Intestinal Epithelial Cell ◽  
Intestinal Epithelial ◽  
Metabolomics Study

scholarly journals Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Caigui Lin ◽  
Zhong Chen ◽  
Lingqiang Zhang ◽  
Zhiliang Wei ◽  
Kian-Kai Cheng ◽  
...  
Keyword(s):  
1H Nmr ◽  
Alveolar Echinococcosis ◽  
Hepatic Alveolar Echinococcosis ◽  
Metabolic Perturbation ◽  
Metabolomics Study

scholarly journals Changes in hepatic metabolic profile during the evolution of STZ-induced diabetic rats via an 1H NMR-based metabonomic investigation

2019 ◽  
Vol 39 (4) ◽  
Author(s):  
Minjiang Chen ◽  
Hong Zheng ◽  
Min Xu ◽  
Liangcai Zhao ◽  
Qianqian Zhang ◽  
...  
Keyword(s):  
Amino Acids ◽  
1H Nmr ◽  
Metabolic Pathways ◽  
Metabolic Profile ◽  
Diabetic Rats ◽  
Proton Nuclear Magnetic Resonance ◽  
Control Group ◽  
Resonance Spectroscopy ◽  
Discriminate Analysis ◽  
Protective Function

Abstract Background: The present study aimed to explore the changes in the hepatic metabolic profile during the evolution of diabetes mellitus (DM) and verify the key metabolic pathways. Methods: Liver samples were collected from diabetic rats induced by streptozotocin (STZ) and rats in the control group at 1, 5, and 9 weeks after STZ administration. Proton nuclear magnetic resonance spectroscopy (1H NMR)-based metabolomics was used to examine the metabolic changes during the evolution of DM, and partial least squares-discriminate analysis (PLS-DA) was performed to identify the key metabolites. Results: We identified 40 metabolites in the 1H NMR spectra, and 11 metabolites were further selected by PLS-DA model. The levels of α-glucose and β-glucose, which are two energy-related metabolites, gradually increased over time in the DM rats, and were significantly greater than those of the control rats at the three-time points. The levels of choline, betaine, and methionine decreased in the DM livers, indicating that the protective function in response to liver injury may be undermined by hyperglycemia. The levels of the other amino acids (leucine, alanine, glycine, tyrosine, and phenylalanine) were significantly less than those of the control group during DM development. Conclusions: Our results suggested that the hepatic metabolic pathways of glucose, choline-betaine-methionine, and amino acids were disturbed during the evolution of diabetes, and that choline-betaine-methionine metabolism may play a key role.

Metabolomics study of Saw palmetto extracts based on 1H NMR spectroscopy

Fitoterapia ◽  
2015 ◽  
Vol 102 ◽  
pp. 56-60 ◽  
Author(s):  
Eric de Combarieu ◽  
Ernesto Marco Martinelli ◽  
Roberto Pace ◽  
Nicola Sardone
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
1H Nmr Spectroscopy ◽  
Saw Palmetto ◽  
Metabolomics Study

scholarly journals 1H NMR metabolomics study of metastatic melanoma in C57BL/6J mouse spleen

Metabolomics ◽  
2014 ◽  
Vol 10 (6) ◽  
pp. 1129-1144 ◽  
Author(s):  
Xuan Wang ◽  
Mary Hu ◽  
Ju Feng ◽  
Maili Liu ◽  
Jian Zhi Hu
Keyword(s):  
Metastatic Melanoma ◽  
1H Nmr ◽  
Mouse Spleen ◽  
Nmr Metabolomics ◽  
Metabolomics Study

scholarly journals Follicular Adenomas Exhibit a Unique Metabolic Profile. 1H NMR Studies of Thyroid Lesions

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e84637 ◽  
Author(s):  
Stanisław Deja ◽  
Tomasz Dawiskiba ◽  
Waldemar Balcerzak ◽  
Magdalena Orczyk-Pawiłowicz ◽  
Mateusz Głód ◽  
...  
Keyword(s):  
1H Nmr ◽  
Metabolic Profile ◽  
Nmr Studies ◽  
Thyroid Lesions

Potential urine biomarkers from a high throughput metabolomics study of severe sepsis in a large Asian cohort

RSC Advances ◽  
2015 ◽  
Vol 5 (124) ◽  
pp. 102204-102209 ◽  
Author(s):  
Qun Liang ◽  
Han Liu ◽  
Tianyu Zhang ◽  
Yan Jiang ◽  
Haitao Xing ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Severe Sepsis ◽  
High Risk ◽  
High Throughput ◽  
High Risk Population ◽  
Convenient Tool ◽  
Urine Biomarkers ◽  
Metabolomics Study ◽  
Asian Cohort ◽  
Urine Metabolome

Non-targeted mass spectrometry was used to characterize peripheral biomarkers associated with the urine metabolome in severe sepsis (SS) patients. This is an efficient and convenient tool for diagnosing and screening of SS in a high-risk population.

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