scholarly journals Environmental release of core–shell semiconductor nanocrystals from free-standing polymer nanocomposite films

2016 ◽  
Vol 3 (3) ◽  
pp. 657-669 ◽  
Author(s):  
Karthik V. Pillai ◽  
Patrick J. Gray ◽  
Chun-Chieh Tien ◽  
Reiner Bleher ◽  
Li-Piin Sung ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Particle Size ◽  
Size Dependence ◽  
Semiconductor Nanocrystals ◽  
Polymer Nanocomposite ◽  
Nanocomposite Films ◽  
Core Shell ◽  
Free Standing ◽  
New Approach

This work presents a new approach to study mechanisms and particle-size dependence of environmental release of nanoparticles from polymer nanocompsites using fluorescent quantum dots.

scholarly journals Synthesis and structure of free-standing germanium quantum dots and their application in live cell imaging

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20566-20573 ◽  
Author(s):  
Ali Karatutlu ◽  
Mingying Song ◽  
Ann P. Wheeler ◽  
Osman Ersoy ◽  
William R. Little ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Shell Structure ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Core Shell ◽  
Free Standing ◽  
Bio Imaging ◽  
Core Shell Structure ◽  
Germanium Quantum Dots ◽  
Unique Core

Colloidally synthesized free-standing Ge qdots with a unique core–shell structure were demonstrated to be a viable bio-imaging probe.

scholarly journals Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on their Optical Properties, Toxicity and Pharmacokinetics

2017 ◽  
Vol 23 (3) ◽  
pp. 340-349 ◽  
Author(s):  
Wafa' T. Al-Jamal
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Photodynamic Therapy ◽  
Biomedical Applications ◽  
Semiconductor Nanocrystals ◽  
Organic Dye ◽  
Surface Coatings ◽  
Core Shell ◽  
Biomedical Field

Quantum dots are semiconducting nanocrystals that exhibit extraordinary optical properties. QD have shown higher photostability compared to standard organic dye type probes. Therefore, they have been heavily explored in the biomedical field. This review will discuss the different approaches to synthesis, solubilise and functionalise QD. Their main biomedical applications in imaging and photodynamic therapy will be highlighted. Finally, QD biodistribution profile and in vivo toxicity will be discussed.

Size Dependence of Temperature-Related Optical Properties of PbS and PbS/CdS Core/Shell Quantum Dots

2014 ◽  
Vol 118 (35) ◽  
pp. 20585-20593 ◽  
Author(s):  
Haiguang Zhao ◽  
Hongyan Liang ◽  
François Vidal ◽  
Federico Rosei ◽  
Alberto Vomiero ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Size Dependence ◽  
Core Shell

scholarly journals Nanoparticles for Bioapplications: Study of the Cytotoxicity of Water Dispersible Quantum Dots

2018 ◽  
Author(s):  
Fatemeh Mirnajafizadeh ◽  
Deborah Ramsey ◽  
Shelli McAlpine ◽  
Fan Wang ◽  
Peter Reece ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Semiconductor Nanocrystals ◽  
Fibroblast Cell ◽  
Hsp90 Inhibitor ◽  
Core Shell ◽  
Human Skin Fibroblast ◽  
Aqueous Synthesis ◽  
Water Dispersible ◽  
Hct 116 ◽  
Hct 116 Cells

Semiconductor nanocrystals or quantum dots (QDs), have unique optical and physical properties that make them potential imaging tools in biological and medical applications. However, concerns such as the aqueous dispersivity, toxicity to cells and stability in biological environments may limit the use of QDs in bioapplications. Here, we report an investigation into the cytotoxicity of aqueously dispersed CdSe(S) and CdSe(S)/ZnO core/shell QDs in the presence of human colorectal carcinoma cells (HCT-116) and a human skin fibroblast cell line (WS-1). The cytotoxicity of the precursor solutions used in the synthesis of the CdSe(S) QDs was also determined in the presence of HCT-116 cells and compared to that of the heat-shock protein (Hsp90) inhibitor, 17-AAG. CdSe(S) QDs were found to have a low toxicity at concentrations up to 100 µg/ml, with a decreased cell viability at higher concentrations, indicating a highly dose-dependent response. Meanwhile, CdSe(S)/ZnO core/shell QDs exhibited lower toxicity than uncoated QDs at higher concentrations. Confocal microscopy images of HCT-116 cells after incubation with CdSe(S) and CdSe(S)/ZnO QDs showed that the cells were stable in aqueous concentrations of 100 µg of QDs per ml, with no sign of cell necrosis, confirming the cytotoxicity data. Key words: HCT-116, WS1, water dispersive QDs, aqueous synthesis, cytotoxicity of QDs.

scholarly journals Nanoparticles for Bioapplications: Study of the Cytotoxicity of Water Dispersible CdSe(S) and CdSe(S)/ZnO Quantum Dots

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 465 ◽  
Author(s):  
Fatemeh Mirnajafizadeh ◽  
Deborah Ramsey ◽  
Shelli McAlpine ◽  
Fan Wang ◽  
John Stride
Keyword(s):  
Quantum Dots ◽  
Semiconductor Nanocrystals ◽  
Fibroblast Cell ◽  
Core Shell ◽  
Human Skin Fibroblast ◽  
Water Dispersible ◽  
Hct 116 ◽  
Low Toxicity ◽  
Hct 116 Cells ◽  
Dose Dependent

Semiconductor nanocrystals or quantum dots (QDs) have unique optical and physical properties that make them potential imaging tools in biological and medical applications. However, concerns over the aqueous dispersivity, toxicity to cells, and stability in biological environments may limit the use of QDs in such applications. Here, we report an investigation into the cytotoxicity of aqueously dispersed CdSe(S) and CdSe(S)/ZnO core/shell QDs in the presence of human colorectal carcinoma cells (HCT-116) and a human skin fibroblast cell line (WS1). The cytotoxicity of the precursor solutions used in the synthesis of the CdSe(S) QDs was also determined in the presence of HCT-116 cells. CdSe(S) QDs were found to have a low toxicity at concentrations up to 100 µg/mL, with a decreased cell viability at higher concentrations, indicating a highly dose-dependent response. Meanwhile, CdSe(S)/ZnO core/shell QDs exhibited lower toxicity than uncoated QDs at higher concentrations. Confocal microscopy images of HCT-116 cells after incubation with CdSe(S) and CdSe(S)/ZnO QDs showed that the cells were stable in aqueous concentrations of 100 µg of QDs per mL, with no sign of cell necrosis, confirming the cytotoxicity data.

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