Probing the interactions of organic molecules, nanomaterials, and microbes with solid surfaces using quartz crystal microbalances: methodology, advantages, and limitations

2017 ◽  
Vol 19 (6) ◽  
pp. 793-811 ◽  
Author(s):  
Rixiang Huang ◽  
Peng Yi ◽  
Yuanzhi Tang

An understanding of the working principle, methodology, advantages and limitations of QCMs is important for their accurate use.

Micromachines ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 463
Author(s):  
Karekin Dikran Esmeryan ◽  
Nikolay Ivanov Stoimenov

Due to the stochastic and time-dependent character of the ice embryo formation and growth (i.e., a process that can be analyzed statistically, but cannot be predicted precisely), the heterogeneous ice nucleation on atmospheric aerosols or macroscopic solid surfaces is still shrouded in mystery, regardless of the extremely active research and exponential progress within this scientific field. For instance, whether the icing appears from outside-in or inside-out is a subject of intense controversy, with practicability in designing passive icephobic coatings or improving the effectiveness of the cryopreservation technologies. Here, we propose an artful technique for quantitative analysis of the different modes of water freezing using super-nonwettable soot-coated quartz crystal microbalances (QCMs). To achieve this goal, a set of 5 MHz QCMs are loaded one at a time with a 50 μL droplet, whose bulk or contour solidification is detected in real-time. The obtained experimental results show that our sensor devices recognize explicitly if the ice nuclei form predominantly at the liquid–solid interface or spread along the droplet’s entire outer shell by triggering individual reproducible responses in terms of the direction of signal evolution in time. Our results may serve as a foundation for the future incorporation of QCM devices in different freezing assays, where gaining information about the ice adhesion forces and ice layer’s thickness is mandatory.


2020 ◽  
Vol 3 (6) ◽  
pp. 5687-5697 ◽  
Author(s):  
Roto Roto ◽  
Aditya Rianjanu ◽  
Annisa Rahmawati ◽  
Innas Amaliya Fatyadi ◽  
Nursidik Yulianto ◽  
...  

Author(s):  
Diego Scaccabarozzi ◽  
Bortolino Saggin ◽  
Marianna Magni ◽  
Pietro Valnegri ◽  
Marco Giovanni Corti ◽  
...  

2011 ◽  
Vol 64 (9) ◽  
pp. 1256 ◽  
Author(s):  
Miroslava Polreichova ◽  
Usman Latif ◽  
Franz L. Dickert

Mass sensitive sensors were applied for fast and label-free detection of bio-analytes. Robust and miniaturized sensor devices were fabricated by combining bio-mimetic imprinted surfaces with quartz crystal microbalances for the analysis of yeast and bacteria cells. These sensors allow us to differentiate between different growing stages of yeast cells. Moreover, the viability of cells was detected by structuring quartz crystal microbalance electrodes like a grid. Artificial yeast cells were produced to pattern the recognition layer, giving reversible enrichment of the respective bio-analytes. This approach was followed to ensure the reproducibility of the identical sensitive material in each case, because the properties of each cell depend on its growth stage, which varies over time. The strategy was further applied to develop a sensitive system for Escherichia coli. Structuring of these materials by soft lithography allows differentiation between cell strains, e.g. E. coli (strain W & B) with a five-fold selectivity.


2010 ◽  
Vol 636-637 ◽  
pp. 1206-1211
Author(s):  
Paulo Inácio ◽  
J.N. Marat-Mendes ◽  
Eugen R. Neagu ◽  
C.J. Dias

Most piezoelectric gravimetric biosensors are based on quartz crystal microbalances or surface acoustic wave devices. In this paper we describe a polymer film system, made of piezoelectric polyvinylidene difluoride (PVDF) and the Immobilon-P membrane (porous PVDF), for biosensing applications. In operation a film is accommodated in a flow cell and connected to an electronic circuit, constituting an oscillatory resonant device; the output signal is its resonance frequency. This device successfully detected the binding between bovine IgG and bovine anti-IgG. Work on the modelling of this film system is presented. Two different approaches are being considered: the finite element method (FEM) and the ABCD matrices. Results comparing theoretical and experimental data are presented.


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