A water-soluble gadolinium metallofullerenol: facile preparation, magnetic properties and magnetic resonance imaging application

2016 ◽  
Vol 45 (21) ◽  
pp. 8696-8699 ◽  
Author(s):  
Jie Li ◽  
Taishan Wang ◽  
Yongqiang Feng ◽  
Ying Zhang ◽  
Mingming Zhen ◽  
...  

A new water-soluble gadolinium metallofullerenol with an enhanced effective magnetic moment and improved T1-weighted relaxivity and magnetic resonance imaging performance in the liver.

RSC Advances ◽  
2015 ◽  
Vol 5 (93) ◽  
pp. 76133-76140 ◽  
Author(s):  
F. Caglieris ◽  
L. Melone ◽  
F. Canepa ◽  
G. Lamura ◽  
F. Castiglione ◽  
...  

Hepta-TEMPO β-CD has a molecular effective magnetic moment of 4.2 μB that is responsible of a NMR relaxivity up to 1.60 mm−1 s−1, not far from the values reported for Gd-based contrast agents, thus resulting a promising candidates as non-toxic MRI contrast agents.


2016 ◽  
Vol 18 (25) ◽  
pp. 16848-16855 ◽  
Author(s):  
Maria F. Casula ◽  
Erika Conca ◽  
Ioanna Bakaimi ◽  
Ayyappan Sathya ◽  
Maria Elena Materia ◽  
...  

A method for water-soluble Mn doped iron oxide clusters and their magnetic properties.


2011 ◽  
Vol 509 (4) ◽  
pp. 1217-1221 ◽  
Author(s):  
Hong Yang ◽  
Xuejian Li ◽  
Hong Zhou ◽  
Yeming Zhuang ◽  
He Hu ◽  
...  

2015 ◽  
Vol 3 (23) ◽  
pp. 5910-5917 ◽  
Author(s):  
Chan Wang ◽  
Yagang Yao ◽  
Qijun Song

The dual optical and magnetic properties of the synthesized Fe3O4@AuNCs were applicable to cancer diagnosis by fluorescence and MR-based imaging.


1988 ◽  
Vol 23 (3) ◽  
pp. 879
Author(s):  
Han Koo Lee ◽  
Sang Hoon Lee ◽  
Heung Sik Kang ◽  
Jong Sup Shim ◽  
Chong Suh Lee ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4053
Author(s):  
Hamid Heydari Sheikh Hossein ◽  
Iraj Jabbari ◽  
Atefeh Zarepour ◽  
Ali Zarrabi ◽  
Milad Ashrafizadeh ◽  
...  

In recent years, the intrinsic magnetic properties of magnetic nanoparticles (MNPs) have made them one of the most promising candidates for magnetic resonance imaging (MRI). This study aims to evaluate the effect of different coating agents (with and without targeting agents) on the magnetic property of MNPs. In detail, iron oxide nanoparticles (IONPs) were prepared by the polyol method. The nanoparticles were then divided into two groups, one of which was coated with silica (SiO2) and hyperbranched polyglycerol (HPG) (SPION@SiO2@HPG); the other was covered by HPG alone (SPION@HPG). In the following section, folic acid (FA), as a targeting agent, was attached on the surface of nanoparticles. Physicochemical properties of nanostructures were characterized using Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), and a vibrating sample magnetometer (VSM). TEM results showed that SPION@HPG was monodispersed with the average size of about 20 nm, while SPION@SiO2@HPG had a size of about 25 nm. Moreover, HPG coated nanoparticles had much lower magnetic saturation than the silica coated ones. The MR signal intensity of the nanostructures showed a relation between increasing the nanoparticle concentrations inside the MCF-7 cells and decreasing the signal related to the T2 relaxation time. The comparison of coating showed that SPION@SiO2@HPG (with/without a targeting agent) had significantly higher r2 value in comparison to Fe3O4@HPG. Based on the results of this study, the Fe3O4@SiO2@HPG-FA nanoparticles have shown the best magnetic properties, and can be considered promising contrast agents for magnetic resonance imaging applications.


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