scholarly journals Early events in the photochemistry of 5-diazo Meldrum's acid: formation of a product manifold in C–N bound and pre-dissociated intersection seam regions

2016 ◽  
Vol 18 (44) ◽  
pp. 30785-30793 ◽  
Author(s):  
Huijing Li ◽  
Annapaola Migani ◽  
Lluís Blancafort ◽  
Quansong Li ◽  
Zesheng Li
Keyword(s):  
Acid Formation ◽  
Product Manifold ◽  
Meldrum's Acid ◽  
Reaction Paths ◽  
Meldrum’S Acid ◽  
Primary Products ◽  
High Level ◽  
Ps Scale

Photolysis of 5-diazo Meldrum's acid yields three different primary products in a sub-ps scale. High-level computations show that this is due to the presence of an extended seam of intersection associated to different reaction paths.

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

scholarly journals Cover Feature: Cp*Rh(III)‐Catalyzed C8 C−H Alkylation of Quinoline N ‐Oxides with Diazo Meldrum's Acid (Eur. J. Org. Chem. 3/2021)

2021 ◽  
Vol 2021 (3) ◽  
pp. 325-325
Author(s):  
Malcolm P. Huestis ◽  
Jean‐Philippe Leclerc ◽  
Robin Larouche‐Gauthier ◽  
Samuel Aubert‐Nicol ◽  
Arun Yadav ◽  
...  
Keyword(s):  
Meldrum's Acid ◽  
Meldrum’S Acid

Structural, Bioactivity, Molecular Docking, Spectroscopic and Electronic Properties of a Synthesized Meldrum's Acid Derivative

2021 ◽  
Vol 6 (19) ◽  
pp. 4698-4718
Author(s):  
Halil Gökce ◽  
Gökhan Alpaslan ◽  
Serdal Kaya ◽  
Nezaket Çakır
Keyword(s):  
Molecular Docking ◽  
Electronic Properties ◽  
Acid Derivative ◽  
Meldrum's Acid ◽  
Meldrum’S Acid

Solvent-free synthesis of novel vanillidene derivatives of Meldrum's acid: biological evaluation, DNA and BSA binding study

RSC Advances ◽  
2016 ◽  
Vol 6 (45) ◽  
pp. 39452-39459 ◽  
Author(s):  
Nenad Janković ◽  
Jovana Muškinja ◽  
Zoran Ratković ◽  
Zorica Bugarčić ◽  
Branislav Ranković ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Solvent Free ◽  
Binding Study ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Bsa Binding ◽  
Solvent Free Conditions ◽  
Derivatives Of ◽  
Solvent Free Synthesis

A series of novel O-alkyl vanillidene derivatives containing Meldrum's acid scaffold under solvent-free conditions were synthesized.

scholarly journals Monoalkylidenes of Meldrum's acid

1984 ◽  
Vol 37 (8) ◽  
pp. 1795 ◽  
Author(s):  
BR Chhabra ◽  
ML Bolte ◽  
WD Crow
Keyword(s):  
Mannich Bases ◽  
Aliphatic Amines ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Acidic Conditions

Meldrum's acid has been found to react with equimolar quantities of aldehydes and secondary cyclic aliphatic amines to yield the corresponding Mannich bases which decompose under acidic conditions to afford the monoalkylidene derivatives in excellent yields.

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