Supracolloidal fullerene-like cages: design principles and formation mechanisms

2016 ◽  
Vol 18 (47) ◽  
pp. 32534-32540 ◽  
Author(s):  
Zhan-Wei Li ◽  
You-Liang Zhu ◽  
Zhong-Yuan Lu ◽  
Zhao-Yan Sun
Keyword(s):  
Self Assembly ◽  
Rational Design ◽  
Design Principles ◽  
The Self ◽  
Formation Mechanisms ◽  
Patch Configuration

A vast collection of fascinating supracolloidal fullerene-like cages has been achievedviathe self-assembly of soft three-patch particles designed to mimic non-planar sp2hybridized carbon atoms in fullerenes, through the rational design of patch configuration, size, and interaction.

scholarly journals Simultaneous analyte indicator binding assay (SBA) for the monitoring of reversible host-guest complexation kinetics

2021 ◽  
Author(s):  
Zsombor Miskolczy ◽  
Mónika Megyesi ◽  
Stephan Sinn ◽  
Frank Biedermann ◽  
Laszlo Biczok
Keyword(s):  
Self Assembly ◽  
Rational Design ◽  
Binding Assay ◽  
Building Blocks ◽  
The Self ◽  
Kinetics Of ◽  
Complexation Kinetics

Very few information is available for the kinetics of the self-assembly and dissociation of optically silent building blocks despite the importance of such data in the rational design of tailor-made...

scholarly journals Tailoring Peptide Self-Assembly and Formation of 2D Nanoribbons on Mica and HOPG Surface

Materials ◽  
2022 ◽  
Vol 15 (1) ◽  
pp. 310
Author(s):  
Hao Kong ◽  
Bin Liu ◽  
Guozheng Yang ◽  
Yun Chen ◽  
Gang Wei
Keyword(s):  
Self Assembly ◽  
Ph Value ◽  
Pyrolytic Graphite ◽  
The Self ◽  
Formation Mechanisms ◽  
Three Dimension ◽  
Material Interfaces ◽  
The Creation ◽  
Assembly Behavior ◽  
And Function

Studying the interactions between biomolecules and material interfaces play a crucial role in the designing and synthesizing of functional bionanomaterials with tailored structure and function. Previously, a lot of studies were performed on the self-assembly of peptides in solution through internal and external stimulations, which mediated the creation of peptide nanostructures from zero-dimension to three-dimension. In this study, we demonstrate the self-assembly behavior of the GNNQQNY peptide on the surface of mica and highly oriented pyrolytic graphite through tailoring the self-assembly conditions. Various factors, such as the type of dissolvent, peptide concentration, pH value, and evaporation period on the formation of peptide nanofibers and nanoribbons with single- and bi-directional arrays are investigated. It is found that the creation of peptide nanoribbons on both mica and HOPG can be achieved effectively through adjusting and optimizing the experimental parameters. Based on the obtained results, the self-assembly and formation mechanisms of peptide nanoribbons on both material interfaces are discussed. It is expected that the findings obtained in this study will inspire the design of motif-specific peptides with high binding affinity towards materials and mediate the green synthesis of peptide-based bionanomaterials with unique function and application potential.

Kinetics-controlled design principles for two-dimensional open lattices using atom-mimicking patchy particles

Nanoscale ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 4544-4551
Author(s):  
Zhan-Wei Li ◽  
Yu-Wei Sun ◽  
Yan-Hui Wang ◽  
You-Liang Zhu ◽  
Zhong-Yuan Lu ◽  
...  
Keyword(s):  
Self Assembly ◽  
Design Principles ◽  
The Self ◽  
Two Dimensional ◽  
Patchy Particles ◽  
Colloid Science

Two-dimensional low-coordinated open lattices, including honeycomb lattices and square-octagon lattices previously unreported in colloid science, are obtained through the self-assembly of atom-mimicking patchy particles.

scholarly journals A class of organic cages featuring twin cavities

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhenyu Yang ◽  
Chunyang Yu ◽  
Junjie Ding ◽  
Lihua Chen ◽  
Huiyu Liu ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Porous Materials ◽  
Self Assembly ◽  
Rational Design ◽  
Three Dimensional ◽  
The Self ◽  
Emergent Properties ◽  
Dynamics Simulations ◽  
Single Cavity

AbstractA variety of organic cages with different geometries have been developed during the last decade, most of them exhibiting a single cavity. In contrast, the number of organic cages featuring a pair of cavities remains scarce. These structures may pave the way towards novel porous materials with emergent properties and functions.We herein report on rational design of a three-dimensional hexaformyl precursor 1, which exhibits two types of conformers, i.e. Conformer-1 and -2, with different cleft positions and sizes. Aided by molecular dynamics simulations, we select two triamino conformation capturers (denoted CC). Small-sized CC-1 selectively capture Conformer-1 by matching its cleft size, while the large-sized CC-2 is able to match and capture both conformers. This strategy allows the formation of three compounds with twin cavities, which we coin diphane. The self-assembly of diphane units results in superstructures with tunable proton conductivity, which reaches up to 1.37×10-5 S cm-1.

scholarly journals Atomic-Scale Investigation on the Evolution of Tio2-Anatase Prepared by a Sonochemical Route and Treated with NaOH

Materials ◽  
2020 ◽  
Vol 13 (3) ◽  
pp. 685
Author(s):  
Berenice Victoria Dimas ◽  
Isaías Hernández Pérez ◽  
Vicente Garibay Garibay Febles ◽  
Lucía Díaz Barriga Díaz Barriga Arceo ◽  
Raúl Suárez Suárez Parra ◽  
...  
Keyword(s):  
Self Assembly ◽  
Thermal Effects ◽  
Ostwald Ripening ◽  
Anatase Phase ◽  
The Self ◽  
Atomic Scale ◽  
Formation Mechanisms ◽  
Sonochemical Synthesis ◽  
Tio2 Anatase ◽  
Self Development

To date, the formation mechanisms of TiO2, as well as its heterostructures, have not been clarified. Moreover, detailed research on the transition from a tetragonal anatase phase to the monoclinic phase of the TiO2(B) phase and their interface structure has been quite limited until now. In the present study, we report on the sonochemical synthesis of TiO2-anatase with a crystallite size of 5.2 ± 1.5 nm under different NaOH concentrations via the hydrothermal method. The use of alkaline solution and the effect of the temperature and reaction time on the formation and structural properties of TiO2-anatase nanopowders were studied. The effects of NaOH concentration on the formation and transformation of titanate structures are subject to thermal effects that stem from the redistribution of energy in the system. These mechanisms could be attributed to three phenomena: (1) the self-assembly of nanofibers and nanosheets, (2) the Ostwald ripening process, and (3) the self-development of hollow TiO2 mesostructures.

Self-limited self-assembly of nanoparticles into supraparticles: towards supramolecular colloidal materials by design

2016 ◽  
Vol 1 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Esteban Piccinini ◽  
Diego Pallarola ◽  
Fernando Battaglini ◽  
Omar Azzaroni
Keyword(s):  
Self Assembly ◽  
Rational Design ◽  
The Self ◽  
Materials By Design ◽  
Colloidal Materials

We survey the most outstanding achievements on the rational design of supraparticles based on the self-limited self-assembly of nanoparticles.

Recent Advances on Paclitaxel-based Self-Delivery Nanomedicine for Cancer Therapy

2020 ◽  
Vol 27 ◽  
Author(s):  
Mengjiao Zhou ◽  
Shupeng Han ◽  
Feifei An
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Self Assembly ◽  
Rational Design ◽  
Water Solubility ◽  
Drug Loading ◽  
The Self ◽  
Drug Molecules ◽  
Recent Advances ◽  
Effective Combination

: Paclitaxel (PTX) is the first natural plant-derived chemotherapeutic drug approved by the Food and Drug Administration. However, the clinical applications of PTX are limited by some drawbacks, such as poor water solubility, rapid blood clearance, nonspecific distribution, and adverse side effects. Nanocarriers have made important contributions for drug delivery and cancer therapy in recent years. However, low drug loading capacity, nanocarrier excipients-induced toxicity or immunogenicity, and complicated synthesis technologies pose a challenge for the clinical application of nanocarriers. To address these issues, the self-delivery nanomedicine (SDNs), in which pure drug molecules directly self-assemble into nanomedicine, have been developed for drug delivery and enhancing antitumor efficacy. In this review, we comprehensively summarize the recent advances on PTX-based SDNs for cancer therapy. First, the self-assembly strategies to develop pure PTX nanodrugs are discussed. Then, the emerging strategies of co-assembly PTX and other therapeutic agents for effective combination therapy are presented, composing of combination chemotherapy, chemo-photothermal therapy, chemophotodynamic therapy, chemo-immunotherapy, and chemo-gene therapy. Finally, the limitations and future outlook of SDNs are discussed. The rational design of these unique nanoplatforms may make a new direction to develop highly efficient drug delivery systems for cancer therapy.

scholarly journals Effect of the proximal secondary sphere on the self-assembly of tetrahedral zinc-oxo clusters

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Michał Terlecki ◽  
Iwona Justyniak ◽  
Michał K. Leszczyński ◽  
Janusz Lewiński
Keyword(s):  
Coordination Sphere ◽  
Self Assembly ◽  
Rational Design ◽  
Supramolecular Assemblies ◽  
The Self ◽  
Intermolecular Hydrogen Bonds ◽  
Secondary Coordination Sphere ◽  
Catalytic Sites ◽  
Solid State Structures ◽  
Metal Oxo Clusters

AbstractMetal-oxo clusters can serve as directional and rigid building units of coordination and noncovalent supramolecular assemblies. Therefore, an in-depth understanding of their multi-faceted chemistry is vital for the development of self-assembled solid-state structures of desired properties. Here we present a comprehensive comparative structural analysis of isostructural benzoate, benzamidate, and new benzamidinate zinc-oxo clusters incorporating the [O,O]-, [O,NH]- and [NH,NH]-anchoring donor centers, respectively. We demonstrated that the NH groups in the proximal secondary coordination sphere are prone to the formation of intermolecular hydrogen bonds, which affects the packing of clusters in the crystal structure. Coordination sphere engineering can lead to the rational design of new catalytic sites and novel molecular building units of supramolecular assemblies.

The Nature of Rapidly Extracted Phycocyanin from the Blue-Green Alga Plectonema Boryanum

1971 ◽  
Vol 29 ◽  
pp. 366-367
Author(s):  
M. Kessel ◽  
R. MacColl
Keyword(s):  
Self Assembly ◽  
Analytical Ultracentrifugation ◽  
Uranyl Acetate ◽  
The Self ◽  
Major Protein ◽  
Subunit Structure ◽  
Blue Green Alga ◽  
Thin Sections ◽  
Blue Green Algae ◽  
Cacodylate Buffer

The major protein of the blue-green algae is the biliprotein, C-phycocyanin (Amax = 620 nm), which is presumed to exist in the cell in the form of distinct aggregates called phycobilisomes. The self-assembly of C-phycocyanin from monomer to hexamer has been extensively studied, but the proposed next step in the assembly of a phycobilisome, the formation of 19s subunits, is completely unknown. We have used electron microscopy and analytical ultracentrifugation in combination with a method for rapid and gentle extraction of phycocyanin to study its subunit structure and assembly.To establish the existence of phycobilisomes, cells of P. boryanum in the log phase of growth, growing at a light intensity of 200 foot candles, were fixed in 2% glutaraldehyde in 0.1M cacodylate buffer, pH 7.0, for 3 hours at 4°C. The cells were post-fixed in 1% OsO4 in the same buffer overnight. Material was stained for 1 hour in uranyl acetate (1%), dehydrated and embedded in araldite and examined in thin sections.

Interrelationship of the cellular distribution and secretion of regular structure (RS) protein in Bacillus licheniformis nm 105

1992 ◽  
Vol 50 (1) ◽  
pp. 712-713
Author(s):  
Xiaorong Zhu ◽  
Richard McVeigh ◽  
Bijan K. Ghosh
Keyword(s):  
Alkaline Phosphatase ◽  
Bacillus Licheniformis ◽  
Self Assembly ◽  
Gel Electrophoresis ◽  
Culture Supernatant ◽  
Regular Structure ◽  
The Self ◽  
Cellular Distribution ◽  
Structural Protein ◽  
Laboratory Cultures

A mutant of Bacillus licheniformis 749/C, NM 105 exhibits some notable properties, e.g., arrest of alkaline phosphatase secretion and overexpression and hypersecretion of RS protein. Although RS is known to be widely distributed in many microbes, it is rarely found, with a few exceptions, in laboratory cultures of microorganisms. RS protein is a structural protein and has the unusual properties to form aggregate. This characteristic may have been responsible for the self assembly of RS into regular tetragonal structures. Another uncommon characteristic of RS is that enhanced synthesis and secretion which occurs when the cells cease to grow. Assembled RS protein with a tetragonal structure is not seen inside cells at any stage of cell growth including cells in the stationary phase of growth. Gel electrophoresis of the culture supernatant shows a very large amount of RS protein in the stationary culture of the B. licheniformis. It seems, Therefore, that the RS protein is cotranslationally secreted and self assembled on the envelope surface.

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