scholarly journals The influence of solution environment on the nucleation kinetics and crystallisability of para-aminobenzoic acid

2016 ◽  
Vol 18 (39) ◽  
pp. 27507-27520 ◽  
Author(s):  
T. D. Turner ◽  
D. M. C. Corzo ◽  
D. Toroz ◽  
A. Curtis ◽  
M. M. Dos Santos ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Solution Thermodynamics ◽  
Aminobenzoic Acid ◽  
Nucleation Kinetics ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Metastable Zone ◽  
Supersaturated Solutions ◽  
Influence Of Solvent

The influence of solvent on the solution thermodynamics, nucleation-kinetics and crystal growth of alpha para-aminobenzoic acid (PABA) crystallising from supersaturated solutions, is examined through analysis of the metastable zone width.

scholarly journals Sugar Industry: Effect of Dextran Concentrations on the Sucrose Crystallization in Aqueous Solutions

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Abdelali Borji ◽  
Fatima-Ezzahra Borji ◽  
Abdelaziz Jourani
Keyword(s):  
Experimental Data ◽  
Aqueous Solutions ◽  
Growth Process ◽  
Sugar Industry ◽  
Nucleation Kinetics ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Industry Effect ◽  
Instantaneous Nucleation ◽  
Metastable Zone

Using the spectrophotometric method, as a new method, the influence of dextran on the sucrose solubility and metastable zone width has been studied. In agreement with the literature the experimental data show that the dextran has a negligible effect on the sucrose solubility. The results also show that this impurity decreases the sucrose metastable zone width. The study of the nucleation kinetics performed, using Nyvlt’s approach, shows that the dextran accelerates the nucleation and that the nuclei are formed in the solution by instantaneous nucleation. The presence of dextran in the system causes a decrease in the growth rate of sucrose. The growth process of sucrose is governed by a Birth and Spread mechanism. The kinetic parameters of sucrose growth in aqueous solutions without and with dextran were estimated.

scholarly journals The Metastability and Nucleation Thresholds of Ibuprofen in Ethanol and Water-Ethanol Mixtures

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Abdur Rashid ◽  
Edward T. White ◽  
Tony Howes ◽  
James D. Litster ◽  
Ivan Marziano
Keyword(s):  
Water Content ◽  
Propanoic Acid ◽  
Secondary Nucleation ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Primary Nucleation ◽  
Metastable Zone ◽  
The Times ◽  
Induction Times ◽  
Supersaturated Solutions

To investigate the crystallization of ibuprofen [((RS)-2-(4-(2-methylpropyl) phenyl) propanoic acid)] from ethanol and water-ethanol mixtures it is necessary to know the nucleation limits of its solutions. In the absence of crystals, nucleation will seldom occur below the PNT (primary nucleation threshold). If crystals are present, nucleation will seldom occur until below the lower SNT (secondary nucleation threshold). Below the SNT, crystals will still grow with negligible nucleation. PNT and SNT values (expressed as relative supersaturationσ) have been measured at 10, 25, and 40°C for ibuprofen in ethanol and in a range of mixtures of different ethanol (E)/water (W) ratios. The induction times were determined from observing the times to nucleate for a range of different supersaturated solutions at a given temperature andE/Wratio. As expected, lowering the supersaturation leads to longer induction times. In ethanol, the SNT values are small and thus the secondary metastable zone width (MSZW) is relatively narrow with a 1 h SNT relative supersaturation typically aboutσ~ 0.05. The 1 h PNT values are much larger with values forσaround 0.3. In aqueous ethanolic mixtures at 25°C, both the PNT and SNT decrease as the water content increases.

Insight into the role of hydrochloric acid in the thermodynamics and nucleation kinetics behavior of Arbidol hydrochloride monohydrate from Metastable Zone Widths

CrystEngComm ◽  
2021 ◽  
Author(s):  
Ting Wen ◽  
Hairong Wang ◽  
Chunrong Li ◽  
Jikun Xu ◽  
Chuntao Zhang
Keyword(s):  
Hydrochloric Acid ◽  
Nucleation Kinetics ◽  
Nucleation Behavior ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Metastable Zone ◽  
Hydrochloride Monohydrate ◽  
Insight Into

In order to investigate the nucleation behavior of arbidol hydrochloride monohydrate (AHM) in the aqueous THF (Tetrahydrofuran) solutions, metastable zone width (MSZW) was experimentally determined via the polythermal method, and...

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