Revisiting an old concept: the coupled oscillator model for VCD. Part 1: the generalised coupled oscillator mechanism and its intrinsic connection to the strength of VCD signals

2016 ◽  
Vol 18 (31) ◽  
pp. 21202-21212 ◽  
Author(s):  
Valentin Paul Nicu
Keyword(s):  
Harmonic Approximation ◽  
Normal Modes ◽  
Oscillator Model ◽  
Coupled Oscillator ◽  
Intrinsic Connection ◽  
Coupled Oscillator Model

This work reports the development of a generalised coupled oscillator expression for VCD that is exact within the harmonic approximation and is applicable to all types of normal modes, regardless whether the considered molecule is symmetric or asymmetric.

Revisiting an old concept: the coupled oscillator model for VCD. Part 2: implications of the generalised coupled oscillator mechanism for the VCD robustness concept

2016 ◽  
Vol 18 (31) ◽  
pp. 21213-21225 ◽  
Author(s):  
Valentin Paul Nicu
Keyword(s):  
Relative Orientation ◽  
Oscillator Model ◽  
Coupled Oscillator ◽  
Displacement Vectors ◽  
The Stability ◽  
Coupled Oscillator Model

The generalised coupled oscillator (GCO) mechanism implies that the stability of the computed VCD sign should be assigned by monitoring the uncertainties in the relative orientation of the GCO fragments and in the nuclear displacement vectors, i.e. not the magnitude of the dissymmetry factor.

Validity of the coupled-oscillator model for laser-array dynamics

1993 ◽  
Vol 18 (21) ◽  
pp. 1810 ◽  
Author(s):  
Herbert G. Winful ◽  
Sean Allen ◽  
Lutfur Rahman
Keyword(s):  
Oscillator Model ◽  
Laser Array ◽  
Coupled Oscillator ◽  
Coupled Oscillator Model

Transient High-Frequency Firing in a Coupled-Oscillator Model of the Mesencephalic Dopaminergic Neuron

2006 ◽  
Vol 95 (2) ◽  
pp. 932-947 ◽  
Author(s):  
Alexey S. Kuznetsov ◽  
Nancy J. Kopell ◽  
Charles J. Wilson
Keyword(s):  
Nmda Receptor ◽  
High Frequency ◽  
Dopaminergic Neurons ◽  
Dopaminergic Neuron ◽  
Receptor Activation ◽  
Oscillator Model ◽  
Coupled Oscillator ◽  
Depolarization Block ◽  
Nmda Receptor Activation ◽  
Coupled Oscillator Model

Dopaminergic neurons of the midbrain fire spontaneously at rates <10/s and ordinarily will not exceed this range even when driven with somatic current injection. When driven at higher rates, these cells undergo spike failure through depolarization block. During spontaneous bursting of dopaminergic neurons in vivo, bursts related to reward expectation in behaving animals, and bursts generated by dendritic application of N-methyl-d-aspartate (NMDA) agonists, transient firing attains rates well above this range. We suggest a way such high-frequency firing may occur in response to dendritic NMDA receptor activation. We have extended the coupled oscillator model of the dopaminergic neuron, which represents the soma and dendrites as electrically coupled compartments with different natural spiking frequencies, by addition of dendritic AMPA (voltage-independent) or NMDA (voltage-dependent) synaptic conductance. Both soma and dendrites contain a simplified version of the calcium-potassium mechanism known to be the mechanism for slow spontaneous oscillation and background firing in dopaminergic cells. The compartments differ only in diameter, and this difference is responsible for the difference in natural frequencies. We show that because of its voltage dependence, NMDA receptor activation acts to amplify the effect on the soma of the high-frequency oscillation of the dendrites, which is normally too weak to exert a large influence on the overall oscillation frequency of the neuron. During the high-frequency oscillations that result, sodium inactivation in the soma is removed rapidly after each action potential by the hyperpolarizing influence of the dendritic calcium-dependent potassium current, preventing depolarization block of the spike mechanism, and allowing high-frequency spiking.

scholarly journals Predicting the effects of deep brain stimulation using a reduced coupled oscillator model

2019 ◽  
Vol 15 (8) ◽  
pp. e1006575 ◽  
Author(s):  
Gihan Weerasinghe ◽  
Benoit Duchet ◽  
Hayriye Cagnan ◽  
Peter Brown ◽  
Christian Bick ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Oscillator Model ◽  
Coupled Oscillator ◽  
Coupled Oscillator Model ◽  
Deep Brain

scholarly journals Fluctuations in a coupled-oscillator model of the cardiovascular system

2007 ◽  
Author(s):  
Jorge A. González ◽  
Jose J. Suárez-Vargas ◽  
Aneta Stefanovska ◽  
Peter V. E. McClintock
Keyword(s):  
Cardiovascular System ◽  
Oscillator Model ◽  
Coupled Oscillator ◽  
Coupled Oscillator Model
Sign in / Sign up

Export Citation Format

Share Document