scholarly journals Insights into enzyme point mutation effect by molecular simulation: phenylethylamine oxidation catalyzed by monoamine oxidase A

2016 ◽  
Vol 18 (19) ◽  
pp. 13346-13356 ◽  
Author(s):  
Gabriel Oanca ◽  
Miha Purg ◽  
Janez Mavri ◽  
Jean C. Shih ◽  
Jernej Stare
Keyword(s):  
Monoamine Oxidase ◽  
Point Mutation ◽  
Molecular Simulation ◽  
Active Site ◽  
Monoamine Oxidase A ◽  
Substrate Molecule

The active site of monoamine oxidase A with a phenylethylamine substrate molecule and residue 335 subjected to mutation.

Interactions of D-amphetamine with the active site of monoamine oxidase-A

2003 ◽  
Vol 11 (2) ◽  
pp. 127-133 ◽  
Author(s):  
Rona R. Ramsay ◽  
Dominic J. B. Hunter
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A

scholarly journals Pirlindole analogs as probes of the active site of Monoamine Oxidase A

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Rona Ruth Ramsay ◽  
Gu Liu ◽  
Nicholas J Westwood
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A

Computer visualisation of the active site of monoamine oxidase-A by means of selective inhibitors

2003 ◽  
Vol 11 (2) ◽  
pp. 135-143
Author(s):  
Alexei E. Medvedev ◽  
Alexis S. Ivanov ◽  
Alexander V. Veselovsky
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A ◽  
Selective Inhibitors

scholarly journals A Spontaneous Point Mutation Produces Monoamine Oxidase A/B Knock-out Mice with Greatly Elevated Monoamines and Anxiety-like Behavior

2004 ◽  
Vol 279 (38) ◽  
pp. 39645-39652 ◽  
Author(s):  
Kevin Chen ◽  
Daniel P. Holschneider ◽  
Weihua Wu ◽  
Igor Rebrin ◽  
Jean C. Shih
Keyword(s):  
Monoamine Oxidase ◽  
Point Mutation ◽  
Monoamine Oxidase A ◽  
Knock Out ◽  
Knock Out Mice

scholarly journals Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

FEBS Journal ◽  
2007 ◽  
Vol 274 (6) ◽  
pp. 1567-1575 ◽  
Author(s):  
Tadeusz Z. E. Jones ◽  
Laura Giurato ◽  
Salvatore Guccione ◽  
Rona R. Ramsay
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A

Influence of Protonation on Substrate and Inhibitor Interactions at the Active Site of Human Monoamine Oxidase-A

2012 ◽  
Vol 52 (5) ◽  
pp. 1213-1221 ◽  
Author(s):  
Gerald Zapata-Torres ◽  
Angelica Fierro ◽  
Sebastian Miranda-Rojas ◽  
Carlos Guajardo ◽  
Patricio Saez-Briones ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A

Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A

Science ◽  
1993 ◽  
Vol 262 (5133) ◽  
pp. 578-580 ◽  
Author(s):  
H. Brunner ◽  
M Nelen ◽  
X. Breakefield ◽  
H. Ropers ◽  
B. van Oost
Keyword(s):  
Monoamine Oxidase ◽  
Point Mutation ◽  
Structural Gene ◽  
Monoamine Oxidase A ◽  
Abnormal Behavior

Membrane Attachment Facilitates Ligand Access to the Active Site in Monoamine Oxidase A

Biochemistry ◽  
2009 ◽  
Vol 48 (25) ◽  
pp. 5864-5873 ◽  
Author(s):  
Rossen Apostolov ◽  
Yasushige Yonezawa ◽  
Daron M. Standley ◽  
Gota Kikugawa ◽  
Yu Takano ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Active Site ◽  
Monoamine Oxidase A ◽  
Membrane Attachment

scholarly journals Analysis of Conserved Active Site Residues in Monoamine Oxidase A and B and Their Three-dimensional Molecular Modeling

2002 ◽  
Vol 277 (19) ◽  
pp. 17209-17216 ◽  
Author(s):  
Rani Maurice Geha ◽  
Kevin Chen ◽  
Johan Wouters ◽  
Frédéric Ooms ◽  
Jean Chen Shih
Keyword(s):  
Molecular Modeling ◽  
Monoamine Oxidase ◽  
Active Site ◽  
Three Dimensional ◽  
Monoamine Oxidase A ◽  
Active Site Residues
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