Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O2: a facile protocol to selectively synthesize 2- and 3-vinylindoles

2017 ◽  
Vol 53 (1) ◽  
pp. 216-219 ◽  
Author(s):  
Bo Cao ◽  
Marwan Simaan ◽  
Ilan Marek ◽  
Yin Wei ◽  
Min Shi
Keyword(s):  
Oxidative Cyclization ◽  
Palladium Catalyzed ◽  
Synthetic Intermediates

A facile and versatile palladium catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O2 to selectively construct important synthetic intermediates 2- and 3-vinylindoles in moderate to good yields has been developed.

Synthesis of novel tetrahydroindeno[1,2-b]pyrrolidines via Ugi multicomponent and palladium-catalyzed aerobic oxidative cyclization

2016 ◽  
Vol 46 (6) ◽  
pp. 509-515 ◽  
Author(s):  
Tannya R. Ibarra-Rivera ◽  
Manuel Alejandro Rentería-Gómez ◽  
Eduardo Nieto-Sepúlveda ◽  
Rocío Gámez-Montaño ◽  
Verónica M. Rivas Galindo ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Palladium Catalyzed

Palladium-Catalyzed Aerobic Oxidative Cyclization of Aliphatic Alkenyl Amides for the Construction of Pyrrolizidine and Indolizidine Derivatives

Synlett ◽  
2017 ◽  
Vol 28 (13) ◽  
pp. 1570-1575 ◽  
Author(s):  
Dan Yang ◽  
Kai-Yip Lo ◽  
Liu Ye
Keyword(s):  
Molecular Oxygen ◽  
Oxidative Cyclization ◽  
Palladium Catalyzed

An efficient palladium-catalyzed aerobic oxidative cyclization has been developed to synthesize a variety of pyrrolizidine and indolizidine derivatives from simple aliphatic alkenyl amides in moderate to good yields. The reaction features the capability of accessing various N-heterocycles and the use of molecular oxygen (1 atm) as the green oxidant.

ChemInform Abstract: Palladium-Catalyzed Oxidative Cyclization of N-Aryl Enamines: From Anilines to Indoles.

ChemInform ◽  
2009 ◽  
Vol 40 (2) ◽  
Author(s):  
Sebastian Wuertz ◽  
Souvik Rakshit ◽  
Julia J. Neumann ◽  
Thomas Droege ◽  
Frank Glorius
Keyword(s):  
Oxidative Cyclization ◽  
Palladium Catalyzed
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