Near infrared photoluminescence modulation of single-walled carbon nanotubes based on a molecular recognition approach

2016 ◽  
Vol 52 (88) ◽  
pp. 12972-12975 ◽  
Author(s):  
Tomohiro Shiraki ◽  
Hisashi Onitsuka ◽  
Tomonari Shiraishi ◽  
Naotoshi Nakashima
Keyword(s):  
Carbon Nanotubes ◽  
Molecular Recognition ◽  
Near Infrared ◽  
Single Walled Carbon Nanotubes ◽  
Single Walled Carbon ◽  
Walled Carbon Nanotubes

The molecular recognition approach has achieved near infrared photoluminescence modulation on locally-functionalized single-walled carbon nanotubes.

scholarly journals Electrostatic-assemblies of single-walled carbon nanotubes and sequence-tunable peptoid polymers detect a lectin protein and its target sugars

2018 ◽  
Author(s):  
Linda Chio ◽  
Jackson Travis Del Bonis-O’Donnell ◽  
Mark A. Kline ◽  
Jae Hong Kim ◽  
Ian R. McFarlane ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Molecular Recognition ◽  
Near Infrared ◽  
Serum Proteins ◽  
Culture Media ◽  
Single Walled Carbon Nanotubes ◽  
Single Walled Carbon ◽  
Lectin Protein ◽  
The Stability ◽  
Walled Carbon Nanotubes

AbstractA primary limitation to real-time imaging of metabolites and proteins has been the selective detection of biomolecules that have no naturally-occurring or stable molecular recognition counterparts. We present developments in the design of synthetic near-infrared fluorescent nanosensors based on the fluorescence modulation of single-walled carbon nanotubes (SWNT) with select sequences of surface-adsorbed N-substituted glycine peptoid polymers. We assess the stability of the peptoid-SWNT nanosensor candidates under variable ionic strengths, protease exposure, and cell culture media conditions, and find that the stability of peptoid-SWNTs depends on the composition and length of the peptoid polymer. From our library, we identify a peptoid-SWNT assembly that can selectively detect lectin protein wheat germ agglutinin (WGA) with a sensitivity comparable to the concentration of serum proteins. This WGA protein nanosensor is characterized with near-infrared spectroscopy and microscopy to study protein-nanosensor interaction parameters. To demonstrate the retention of nanosensor-bound protein activity, we show that WGA on the nanosensor produces an additional fluorescent signal modulation upon exposure to the lectin’s conjugate sugars, suggesting the lectin protein selectively binds its target sugars through ternary molecular recognition interactions relayed to the nanosensor. Our results inform design considerations for developing synthetic molecular recognition elements by assembling peptoid polymers on SWNTs, and also demonstrate these assemblies can serve as optical nanosensors for lectin proteins and their target sugars. Together, these data suggest certain peptoid sequences can be assembled with SWNTs to serve as versatile optical probes to detect proteins and their molecular substrates.

scholarly journals In vivo biosensing via tissue-localizable near-infrared-fluorescent single-walled carbon nanotubes

2013 ◽  
Vol 8 (11) ◽  
pp. 873-880 ◽  
Author(s):  
Nicole M. Iverson ◽  
Paul W. Barone ◽  
Mia Shandell ◽  
Laura J. Trudel ◽  
Selda Sen ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Near Infrared ◽  
Single Walled Carbon Nanotubes ◽  
Single Walled Carbon ◽  
Walled Carbon Nanotubes

scholarly journals Enhancing near-infrared photoluminescence from single-walled carbon nanotubes by defect-engineering using benzoyl peroxide

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lukasz Przypis ◽  
Maciej Krzywiecki ◽  
Yoshiaki Niidome ◽  
Haruka Aoki ◽  
Tomohiro Shiraki ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Conjugated Polymers ◽  
Near Infrared ◽  
Light Emission ◽  
Single Walled Carbon Nanotubes ◽  
Organic Radical ◽  
Defect Engineering ◽  
Single Walled Carbon ◽  
Walled Carbon Nanotubes ◽  
Selection Of

AbstractSingle-walled carbon nanotubes (SWCNTs) have been modified with ester groups using typical organic radical chemistry. Consequently, traps for mobile excitons have been created, which enhanced the optical properties of the material. The proposed methodology combines the benefits of mainstream approaches to create luminescent defects in SWCNTs while it simultaneously avoids their limitations. A step change was achieved when the aqueous medium was abandoned. The selection of an appropriate organic solvent enabled much more facile modification of SWCNTs. The presented technique is quick and versatile as it can engage numerous reactants to tune the light emission capabilities of SWCNTs. Importantly, it can also utilize SWCNTs sorted by chirality using conjugated polymers to enhance their light emission capabilities. Such differentiation is conducted in organic solvents, so monochiral SWCNT can be directly functionalized using the demonstrated concept in the same medium without the need to redisperse the material in water.

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