Solvent-dependent copper-catalyzed synthesis of pyrazoles under aerobic conditions

2016 ◽  
Vol 52 (98) ◽  
pp. 14093-14096 ◽  
Author(s):  
Florian Pünner ◽  
Yoshihiro Sohtome ◽  
Mikiko Sodeoka
Keyword(s):  
Oxidative Cyclization ◽  
Selective Synthesis ◽  
Aerobic Conditions

We have developed a copper-catalyzed oxidative cyclization of hydrazones under aerobic conditions, enabling solvent-dependent selective synthesis of different pyrazoles.

scholarly journals An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization

Synlett ◽  
2018 ◽  
Vol 29 (13) ◽  
pp. 1717-1722 ◽  
Author(s):  
Manjula Alla ◽  
Gal Potuganti ◽  
Divakar Indukuri
Keyword(s):  
Bond Formation ◽  
Nitrogen Sources ◽  
Oxidative Cyclization ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Aerobic Conditions ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields.

Iodine-Mediated Oxidative Cyclization of 2-(Pyridin-2-yl)acetate Derivatives with Alkynes: Condition-Controlled Selective Synthesis of Multisubstituted Indolizines

Synthesis ◽  
2019 ◽  
Vol 52 (03) ◽  
pp. 459-470 ◽  
Author(s):  
Lisheng He ◽  
Yuzhu Yang ◽  
Xiaolan Liu ◽  
Guangyan Liang ◽  
Chunyan Li ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Cyclization Reaction ◽  
Selective Synthesis ◽  
Reaction Conditions ◽  
Stepwise Synthesis

An iodine-mediated oxidative cyclization reaction between 2-(pyridin-2-yl)acetate derivatives and different alkynes has been developed, which provides regioselective and chemoselective syntheses of multiply substituted indolizines under modified reaction conditions. Plausible mechanisms have been proposed to explain the selective syntheses of indolizines. This protocol can be also applied to the stepwise synthesis of 2,2′-biindolizines.

Synthesis of 2-Arylquinoxalines: Triarylstibane-Catalyzed Oxidative Cyclization of α-Hydroxy Ketones with 1,2-Diamines under Aerobic Conditions

Heterocycles ◽  
2016 ◽  
Vol 93 (1) ◽  
pp. 75 ◽  
Author(s):  
Shuji Yasuike ◽  
Rie Takada ◽  
Mio Matsumura ◽  
Yuu Ukai ◽  
Mizuki Yamada ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Aerobic Conditions ◽  
Hydroxy Ketones

Copper catalyzed aerobic oxidative cyclization and ketonization: one pot synthesis of benzoimidazo[1,2-a]imidazolones

2016 ◽  
Vol 52 (39) ◽  
pp. 6621-6624 ◽  
Author(s):  
Manikandan Selvaraju ◽  
Tzuen-Yang Ye ◽  
Chia-Hsin Li ◽  
Pei-Heng Ho ◽  
Chung-Ming Sun
Keyword(s):  
Oxidative Cyclization ◽  
Terminal Alkyne ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aerobic Conditions ◽  
Highly Efficient ◽  
One Pot Synthesis

A highly efficient synthesis of benzoimidazo[1,2-a]imidazolone through a novel oxidative 5-exo-dig cyclization-ketonization cascade of 2-aminobenzimidazole, aldehyde and terminal alkyne has been explored under aerobic conditions.

Rhodium-catalyzed tunable oxidative cyclization toward the selective synthesis of α-pyrones and furans

2016 ◽  
Vol 52 (8) ◽  
pp. 1661-1664 ◽  
Author(s):  
Jiaping Wu ◽  
Dongxu Wang ◽  
Yanjun Wan ◽  
Cheng Ma
Keyword(s):  
Oxidative Cyclization ◽  
Diazo Compounds ◽  
Selective Synthesis ◽  
Substituted Furans

The RhIII-catalyzed tunable oxidative cyclization of readily availableN-tosylacrylamides and diazo compounds toward the selective synthesis of fully substituted furans and α-pyrones is presented.

Cross-dehydrogenative C(sp3)–C(sp3) coupling via C–H activation using magnetically retrievable ruthenium-based photoredox nanocatalyst under aerobic conditions

2019 ◽  
Vol 55 (51) ◽  
pp. 7402-7405 ◽  
Author(s):  
Pooja Rana ◽  
Rashmi Gaur ◽  
Radhika Gupta ◽  
Gunjan Arora ◽  
A. Jayashree ◽  
...  
Keyword(s):  
Selective Synthesis ◽  
Aerobic Conditions ◽  
Heterogeneous Nanocatalyst

A robust, magnetically retrievable photoredox Ru-based heterogeneous nanocatalyst was fabricated for the highly regio-selective synthesis of N-aryl-tetrahydroisoquinoline derivatives.

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