scholarly journals Qualitative sensing of mechanical damage by a fluorogenic “click” reaction

2016 ◽  
Vol 52 (74) ◽  
pp. 11076-11079 ◽  
Author(s):  
Diana Döhler ◽  
Sravendra Rana ◽  
Harald Rupp ◽  
Henrik Bergmann ◽  
Shahed Behzadi ◽  
...  
Keyword(s):  
Click Reaction ◽  
Cycloaddition Reaction ◽  
Mechanical Damage ◽  
Self Healing ◽  
Physical Damage ◽  
Strong Fluorescence ◽  
Damage Sensing

A simple and unique damage-sensing tool mediated by a Cu(i)-catalyzed [3+2] cycloaddition reaction is reported, where a fluorogenic “click”-reaction highlights physical damage by a strong fluorescence increase accompanied by in situ monitoring of localized self-healing.

scholarly journals Self-triggered click reaction in an Alzheimer's disease model:in situbifunctional drug synthesis catalyzed by neurotoxic copper accumulated in amyloid-β plaques

2019 ◽  
Vol 10 (44) ◽  
pp. 10343-10350 ◽  
Author(s):  
Zhi Du ◽  
Dongqin Yu ◽  
Xiubo Du ◽  
Peter Scott ◽  
Jinsong Ren ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neurodegenerative Diseases ◽  
Click Reaction ◽  
Cycloaddition Reaction ◽  
Amyloid Β ◽  
Drug Synthesis ◽  
Insight Into

Accumulated Cu in amyloid-β plaques can effectively catalyze the azide–alkyne cycloaddition reaction for fluorophore activation and drug synthesis. Our work may provide new insight intoin situdrug synthesis for neurodegenerative diseases.

In Situ Forming, Dual-Crosslink Network, Self-Healing Hydrogel Enabled by a Bioorthogonal Nopoldiol–Benzoxaborolate Click Reaction with a Wide pH Range

2019 ◽  
Vol 31 (11) ◽  
pp. 4092-4102 ◽  
Author(s):  
Di Wu ◽  
Wenda Wang ◽  
Diana Diaz-Dussan ◽  
Yi-Yang Peng ◽  
Yangjun Chen ◽  
...  
Keyword(s):  
Click Reaction ◽  
Self Healing ◽  
In Situ Forming ◽  
Wide Ph Range ◽  
Ph Range

scholarly journals Repair Performance of Self-Healing Microcapsule/Epoxy Resin Insulating Composite to Physical Damage

2019 ◽  
Vol 9 (19) ◽  
pp. 4098 ◽  
Author(s):  
Youyuan Wang ◽  
Yudong Li ◽  
Zhanxi Zhang ◽  
Haisen Zhao ◽  
Yanfang Zhang
Keyword(s):  
Epoxy Resin ◽  
Molecular Diffusion ◽  
Breakdown Strength ◽  
Mechanical Damage ◽  
Electrical Equipment ◽  
Physical Structure ◽  
Self Healing ◽  
Physical Damage ◽  
Repair Rate ◽  
Electrical Tree

Minor physical damage can reduce the insulation performance of epoxy resin, which seriously threatens the reliability of electrical equipment. In this paper, the epoxy resin insulating composite was prepared by a microcapsule system to achieve its self-healing goal. The repair performance to physical damage was analyzed by the tests of scratch, cross-section damage, electric tree, and breakdown strength. The results show that compared with pure epoxy resin, the composite has the obvious self-healing performance. For mechanical damage, the maximum repair rate of physical structure is 100%, and the breakdown strength can be restored to 83% of the original state. For electrical damage, microcapsule can not only attract the electrical tree and inhibit its propagation process, but also repair the tubules of electrical tree effectively. Moreover, the repair rate is fast, which meets the application requirements of epoxy resin insulating material. In addition, the repair behavior is dominated by capillarity and molecular diffusion on the defect surface. Furthermore, the electrical properties of repaired part are greatly affected by the characteristics of damage interface and repair product. In a word, the composite shows better repair performance to physical damage, which is conducive to improving the reliability of electrical insulating materials.

DNA‐Compatible Click Reaction Employing In Situ Generated Azides from Boronic Acids

2021 ◽  
Vol 1 (5) ◽  
Author(s):  
Yulong An ◽  
Hao Yan ◽  
Zhenzhen Dong ◽  
Alexander L. Satz
Keyword(s):  
Click Reaction ◽  
Boronic Acids

Recyclable conductive nanoclay for direct in situ printing flexible electronics

2021 ◽  
Author(s):  
Pengcheng Wu ◽  
Zhenwei Wang ◽  
Xinhua Yao ◽  
Jianzhong Fu ◽  
Yong He
Keyword(s):  
Flexible Electronics ◽  
Self Healing ◽  
Stamping Process

A recyclable, self-healing conductive nanoclay and corresponding stamping process are developed for printing flexible electronics directly and quickly in situ.

In situ 1,3-dipolar azide cycloaddition reaction: synthesis of functionalized d-glucose based chiral piperidine and oxazepine analogues

Tetrahedron ◽  
2004 ◽  
Vol 60 (23) ◽  
pp. 4959-4965 ◽  
Author(s):  
Subhankar Tripathi ◽  
Kaushik Singha ◽  
Basudeb Achari ◽  
Sukhendu B Mandal
Keyword(s):  
Cycloaddition Reaction ◽  
Reaction Synthesis

SELF-HEALING OF WOVEN COMPOSITE LAMINATES VIA IN SITU THERMAL REMENDING

2021 ◽  
Author(s):  
ALEXANDER D. SNYDER ◽  
ZACHARY J. PHILLIPS ◽  
JASON F. PATRICK
Keyword(s):  
Composite Laminates ◽  
Composite Laminate ◽  
Laminated Composites ◽  
Reaction Times ◽  
Carbon Fiber Composites ◽  
Self Healing ◽  
Damage Mode ◽  
Woven Composite ◽  
Internal Damage

Fiber-reinforced polymer composites are attractive structural materials due to their high specific strength/stiffness and excellent corrosion resistance. However, the lack of through-thickness reinforcement in laminated composites creates inherent susceptibility to fiber-matrix debonding, i.e., interlaminar delamination. This internal damage mode has proven difficult to detect and nearly impossible to repair via conventional methods, and therefore, remains a significant factor limiting the reliability of composite laminates in lightweight structures. Thus, novel approaches for mitigation (e.g., self-healing) of this incessant damage mode are of tremendous interest. Self-healing strategies involving sequestration of reactive liquids, i.e. microcapsule and microvascular systems, show promise for the extending service- life of laminated composites. However, limited heal cycles, long reaction times (hours/days), and variable stability of chemical agents under changing environmental conditions remain formidable research challenges. Intrinsic self- healing approaches that utilize reversible bonds in the host material circumvent many of these limitations and offer the potential for unlimited heal cycles. Here we detail the development of an intrinsic self-healing woven composite laminate based on thermally-induced dynamic bond re-association of 3D-printed polymer interlayers. In contrast to prior work, self-repair of the laminate occurs in situ and below the glass-transition temperature of the epoxy matrix, and maintains >85% of the elastic modulus during healing. This new platform has been deployed in both glass and carbon-fiber composites, demonstrating application versatility. Remarkably, up to 20 rapid (minute-scale) self-healing cycles have been achieved with healing efficiencies hovering 100% of the interlayer toughened (4-5x) composite laminate. This latest self-healing advancement exhibits unprecedented potential for perpetual in-service repair along with material multi-functionality (e.g., deicing ability) to meet modern application demands.

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