Fmoc solid-phase synthesis of C-terminal modified peptides by formation of a backbone cyclic urethane moiety

2016 ◽  
Vol 52 (62) ◽  
pp. 9699-9702 ◽  
Author(s):  
Hader E. Elashal ◽  
Ryan D. Cohen ◽  
Monika Raj
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Modified Peptides ◽  
Fmoc Solid Phase Synthesis

A universal strategy for solid phase synthesis of various C-terminal modified peptides independent of type of resins, unnatural linkers, and handles is developed. Semi-permanent protection at the C-termini of peptides is also afforded by the method described.

Backbone Amide Linker Strategies for the Solid-Phase Synthesis of C-Terminal Modified Peptides

ChemInform ◽  
2006 ◽  
Vol 37 (9) ◽  
Author(s):  
Jordi Alsina ◽  
Steven A. Kates ◽  
George Barany ◽  
Fernando Albericio
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Backbone Amide ◽  
Modified Peptides ◽  
Backbone Amide Linker

Solid-phase synthesis ofC-terminally modified peptides

2006 ◽  
Vol 12 (11) ◽  
pp. 686-692 ◽  
Author(s):  
Hefziba T. Ten Brink ◽  
Joris T. Meijer ◽  
Remon V. Geel ◽  
Mark Damen ◽  
Dennis W. P. M. Löwik ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Modified Peptides
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