Cancer cell-targeted two-photon fluorescence probe for the real-time ratiometric imaging of DNA damage

2016 ◽  
Vol 52 (37) ◽  
pp. 6308-6311 ◽  
Author(s):  
Hua Zhang ◽  
Kui Wang ◽  
Xiaopeng Xuan ◽  
Qingzhang Lv ◽  
Yamin Nie ◽  
...  
Keyword(s):  
Dna Damage ◽  
Cancer Cells ◽  
Real Time ◽  
Cancer Cell ◽  
Fluorescence Probe ◽  
The Real ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

A sequential ICT fluorescence probe (ANF–Glu) was successfully utilized to spatially and temporally image DNA damage in cancer cells.

Enhanced Two-Photon Fluorescence Imaging and Therapy of Cancer Cells via Gold@Bridged Silsesquioxane Nanoparticles

Small ◽  
2014 ◽  
Vol 11 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Jonas Croissant ◽  
Marie Maynadier ◽  
Olivier Mongin ◽  
Vincent Hugues ◽  
Mireille Blanchard-Desce ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Two Photon ◽  
Bridged Silsesquioxane ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Imaging of formaldehyde fluxes in epileptic brains with a two-photon fluorescence probe

2020 ◽  
Vol 56 (27) ◽  
pp. 3871-3874
Author(s):  
Jian Chen ◽  
Chenwen Shao ◽  
Xueao Wang ◽  
Jin Gu ◽  
Hai-Liang Zhu ◽  
...  
Keyword(s):  
Animal Models ◽  
Fluorescence Probe ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence ◽  
Epigenetic Processes

A two-photon (TP) fluorescence probe has been developed for imaging endogenous FA fluxes during metabolic and epigenetic processes in animal models, especially in live brains.

A water-soluble two-photon fluorescence chemosensor for ratiometric imaging of mitochondrial viscosity in living cells

2016 ◽  
Vol 4 (35) ◽  
pp. 5907-5912 ◽  
Author(s):  
Meng Zhao ◽  
Yingzhong Zhu ◽  
Jian Su ◽  
Qian Geng ◽  
Xiaohe Tian ◽  
...  
Keyword(s):  
Living Cells ◽  
Water Soluble ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

We report a novel water-soluble ratiometric TPEF chemosensor EIN that is specifically responsive and singularly sensitive to mitochondria viscosity in living cells.

A Red Emissive Two‐Photon Fluorescence Probe Based on Carbon Dots for Intracellular pH Detection

Small ◽  
2019 ◽  
Vol 15 (48) ◽  
pp. 1901673 ◽  
Author(s):  
Xiaoxue Ye ◽  
Yunhui Xiang ◽  
Qirong Wang ◽  
Zhen Li ◽  
Zhihong Liu
Keyword(s):  
Intracellular Ph ◽  
Carbon Dots ◽  
Fluorescence Probe ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence ◽  
Ph Detection

Open-Chain Crown-Ether-Derived Two-Photon Fluorescence Probe for Real-Time Dynamic Biopsy of Mercury Ions

2017 ◽  
Vol 70 (6) ◽  
pp. 705
Author(s):  
Chibao Huang ◽  
Daohai Zhang ◽  
Junle Qu ◽  
Xiaonan Liu ◽  
Guanglian Zhao ◽  
...  
Keyword(s):  
Water Solubility ◽  
Fluorescence Probe ◽  
Stokes Shift ◽  
Cell Permeability ◽  
Photon Absorption ◽  
Live Cells ◽  
Open Chain ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

A novel two-photon fluorescence probe for Hg2+ derived from bis(styryl)terephthalonitrile, as a two-photon fluorophore, and bis[2-(2-hydroxyethyl sulfanyl) ethyl]amino group (ionophore), as a novel Hg2+ ligand, was developed. The probe possesses small molecule size, large two-photon absorption cross-section (1067 GM) in H2O, non-cytotoxic effect, long wavelength emission at 588 nm, large Stokes shift (121 nm), excellent photostability, high water solubility, good cell permeability, and pH insensitivity in the biologically relevant range. The probe can selectively detect Hg2+ ions in live cells and living tissues without interference from other metal ions and the membrane-bound probes, and its quenching constant is 8.73 × 105 M–1.

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