The construction of functional protein nanotubes by small molecule-induced self-assembly of cricoid proteins

2016 ◽  
Vol 52 (21) ◽  
pp. 4092-4095 ◽  
Author(s):  
Lu Miao ◽  
Qiusheng Fan ◽  
Linlu Zhao ◽  
Qinglong Qiao ◽  
Xiyu Zhang ◽  
...  
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Functional Protein ◽  
Covalent Crosslinking ◽  
Gpx Activity ◽  
Protein Nanotubes

Induced by small molecular ethylenediamine and “zero-length” covalent crosslinking, covalently crosslinked SeSP1 protein nanotubes with great GPx activity was fabricated.

Chitosan Nanocarriers Loading Anti-Tumor Drugs

2015 ◽  
Vol 32 ◽  
pp. 113-127 ◽  
Author(s):  
Ji Wei Wu ◽  
Xin Feng Song ◽  
Han Wen Sun ◽  
Yan Cong Zhang ◽  
Xiang Ling Gu ◽  
...  
Keyword(s):  
Self Assembly ◽  
Drug Carrier ◽  
The Body ◽  
Natural Polymer ◽  
Preparation Methods ◽  
Ionic Crosslinking ◽  
Covalent Crosslinking ◽  
Immune Ability ◽  
Tumor Drugs ◽  
Adhesion Effect

Chitosan is a kind of natural polymer commonly applied for nanomaterials, which is affluent in nature with favorable biodegradability and biocompatibility and free of toxicity or odor. In clinic it can be used as a drug carrier for the treatment of cancer, and also it is a kind of new pharmaceutical excipient. To prepare chitosan nanomaterial, various method are used, such as ionic crosslinking, covalent crosslinking, precipitation, free radical polymerization, reverse micelle, spray drying, and self-assembly. Furthermore, plenty of anti-tumor drugs, including adriamycin, epirubicin, taxol, 5-fluorouracil, norcantharidin, folic acid, and so on, are also attempted to load on these chitosan nanocarriers. In addition, the mechanism for those nanocarriers carrying anti-tumor drugs acting on tumor cell were explored, and the formulation mainly include electric charge adhesion effect, suppressing the proliferation of tumor cells, adjusting or enhancing immune ability of the body and inducing apoptosis. This paper compared the characteristics of different preparation methods on chitosan as a nanodrug carrier, summarized the types of packaged drugs, analyzed the mechanism of the chitosan as nanodrug carriers. It can provide valuable reference for researchers' further work.

Controlled self-assembly of small molecule probes and the related applications in bioanalysis

2016 ◽  
Vol 76 ◽  
pp. 38-53 ◽  
Author(s):  
Yongxin Li ◽  
Huipeng Zhou ◽  
Jian Chen ◽  
Sohail Anjum Shahzad ◽  
Cong Yu
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Small Molecule Probes

scholarly journals Aqueous interfacial gels assembled from small molecule supramolecular polymers

2017 ◽  
Vol 8 (2) ◽  
pp. 1350-1355 ◽  
Author(s):  
Alexander S. Groombridge ◽  
Aniello Palma ◽  
Richard M. Parker ◽  
Chris Abell ◽  
Oren A. Scherman
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Self Assembly ◽  
Hyperbranched Polymer ◽  
Soft Matter ◽  
Supramolecular Polymers ◽  
Supramolecular Network ◽  
Self Healing ◽  
Liquid Interfaces ◽  
Stimuli Responsive

The successful self-assembly of a stimuli-responsive aqueous supramolecular hyperbranched polymer from small molecules and the macrocyclic host cucurbit[8]uril (CB[8]) is reported. This self-healing supramolecular network can act as a soft matter barrier at liquid–liquid interfaces.

Closing the Loop: Triazolylpyridine Coordination Drives the Self‐Assembly of Metallomacrocycles with Tunable Topologies for Small‐Molecule and Guanine‐Quadruplex Recognition

2018 ◽  
Vol 24 (70) ◽  
pp. 18718-18734 ◽  
Author(s):  
Caitlin E. Miron ◽  
Madelaine R. Colden Leung ◽  
Emily I. Kennedy ◽  
Olivier Fleischel ◽  
Mona Ashraf Khorasani ◽  
...  
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
The Self ◽  
Guanine Quadruplex ◽  
Closing The Loop

Small molecule-mediated self-assembly behaviors of Pluronic block copolymers in aqueous solution: impact of hydrogen bonding on the morphological transition of Pluronic micelles

Soft Matter ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. 142-151 ◽  
Author(s):  
Haiyan Luo ◽  
Kun Jiang ◽  
Xiangfeng Liang ◽  
Huizhou Liu ◽  
Yingbo Li
Keyword(s):  
Aqueous Solution ◽  
Hydrogen Bonding ◽  
Block Copolymers ◽  
Small Molecules ◽  
Small Molecule ◽  
Propyl Gallate ◽  
Self Assembly ◽  
Morphological Transition ◽  
Propyl Paraben ◽  
Pluronic P123

The influence of hydrogen bonding on the morphological transition of Pluronic P123 micelles is experimentally and theoretically investigated by introducing three small molecules, i.e. propyl benzoate (PB), propyl paraben (PP) and propyl gallate (PG).

Charge-Transport Networks via Small-Molecule Self-Assembly in Conjugated Polymer Bulk Heterojunctions

2019 ◽  
Vol 123 (45) ◽  
pp. 27305-27316
Author(s):  
Michael Roders ◽  
Matthew A. Kolaczkowski ◽  
William R. Hollingsworth ◽  
Reilly Seban ◽  
Yi Liu ◽  
...  
Keyword(s):  
Charge Transport ◽  
Small Molecule ◽  
Self Assembly ◽  
Conjugated Polymer ◽  
Bulk Heterojunctions ◽  
Transport Networks ◽  
Polymer Bulk

Small molecule induced self-assembly of Au nanoparticles

2011 ◽  
Vol 21 (42) ◽  
pp. 16935 ◽  
Author(s):  
Jaewook Lee ◽  
Hongjian Zhou ◽  
Jaebeom Lee
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Au Nanoparticles

Impact of self-assembly on the photovoltaic properties of a small molecule oligothiophene donor

Solar Energy ◽  
2020 ◽  
Vol 195 ◽  
pp. 223-229 ◽  
Author(s):  
Amanpreet Kaur Hundal ◽  
Anubha Agarwal ◽  
Mohammed A. Jameel ◽  
Salman Ali ◽  
Jing-Yu Chen ◽  
...  
Keyword(s):  
Small Molecule ◽  
Self Assembly ◽  
Photovoltaic Properties
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