Magnetically recoverable Cu0/Fe3O4catalyzed highly regioselective synthesis of 2,3,4-trisubstituted pyrroles from unactivated terminal alkynes and isocyanides

2016 ◽  
Vol 52 (25) ◽  
pp. 4675-4678 ◽  
Author(s):  
Dipak Kumar Tiwari ◽  
Mandalaparthi Phanindrudu ◽  
Vinod Kumar Aravilli ◽  
B. Sridhar ◽  
Pravin R. Likhar ◽  
...  
Keyword(s):  
Regioselective Synthesis ◽  
Terminal Alkynes ◽  
One Pot

An efficient, one pot tandem, Cu0/Fe3O4catalyzed highly regioselective synthesis of 2,3,4-trisubstituted pyrroles from unactivated terminal alkynes and isocyanides.

Polystyrene resin supported palladium(0) (Pd@PR) nanocomposite mediated regioselective synthesis of 4-aryl-1-alkyl/(2-haloalkyl)-1H-1,2,3-triazoles and their N-vinyl triazole derivatives from terminal alkynes

RSC Advances ◽  
2015 ◽  
Vol 5 (15) ◽  
pp. 11506-11514 ◽  
Author(s):  
Arun K. Shil ◽  
Sandeep Kumar ◽  
Saurabh Sharma ◽  
Abha Chaudhary ◽  
Pralay Das
Keyword(s):  
Regioselective Synthesis ◽  
Terminal Alkynes ◽  
One Pot ◽  
Triazole Derivatives ◽  
General Methodology ◽  
One Pot Synthesis ◽  
Supported Palladium ◽  
Polystyrene Resin

An efficient general methodology has been developed for sequential one-pot synthesis of 4-aryl-1-alkyl-1H-1,2,3-triazoles influenced by Pd@PR nanocomposite.

ChemInform Abstract: A Three-Component Domino Reaction of 2-Tetralone, Hydroxylamine and Acetylene: A One-Pot, Highly Regioselective Synthesis of 4,5-Dihydrobenz[e]indoles.

ChemInform ◽  
2010 ◽  
Vol 41 (28) ◽  
pp. no-no
Author(s):  
Alexander M. Vasil'tsov ◽  
Andrei V. Ivanov ◽  
Al'bina I. Mikhaleva ◽  
Boris A. Trofimov
Keyword(s):  
Regioselective Synthesis ◽  
Domino Reaction ◽  
One Pot

One-pot Synthesis of α,β-Unsaturated Ketones through Sequential Alkyne Dimerization/Hydration Reactions using Hoveyda-Grubbs Catalyst

2021 ◽  
Author(s):  
Bengi Öztürk ◽  
Begüm Sarıaslan ◽  
Mina Aşkun ◽  
Zeynep Tunalı ◽  
Solmaz Karabulut
Keyword(s):  
Regioselective Synthesis ◽  
Grubbs Catalyst ◽  
One Pot ◽  
Unsaturated Ketones ◽  
One Pot Synthesis

Herein we report a sequential one-pot alkyne dimerization/hydration protocol for the regioselective synthesis of α,β-unsaturated ketones in quantitive yields. The alkyne dimerization reactions of terminal arylacetylenes proceeded with high regioselectivity...

One-Pot Synthesis of Symmetrical and Asymmetrical 3-Amino Diynes via Cu(I)-Catalyzed Reaction of Enaminones with Terminal Alkynes

2021 ◽  
Author(s):  
Changyuan Zhang ◽  
Huosheng Guo ◽  
Lulu Chen ◽  
Jiantao Zhang ◽  
Mengping Guo ◽  
...  
Keyword(s):  
Terminal Alkynes ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation

2017 ◽  
Vol 67 (3) ◽  
pp. 309-324 ◽  
Author(s):  
Nadjet Rezki ◽  
Mohamed Reda Aouad
Keyword(s):  
Antimicrobial Activity ◽  
Cycloaddition Reaction ◽  
Dipolar Cycloaddition ◽  
Terminal Alkynes ◽  
One Pot ◽  
Alkyl Aryl ◽  
Antimicrobial Evaluation ◽  
Ultrasound Assisted ◽  
Click Synthesis

AbstractThe present study describes an efficient and ecofriendly, ultrasound, one-pot click cycloaddition approach for the construction of a novel series of 1,4-disubstituted-1,2,3-triazoles tethered with fluorinated 1,2,4-triazole-benzothiazole molecular conjugates. It involved three-component condensation of the appropriate bromoacetamide benzothiazole, sodium azide and 4-alkyl/aryl-5-(2-fluorophenyl)-3-(prop-2-ynylthio)-1,2,4-triazoles4a-ethrough a Cu(I)-catalyzed 1,3-dipolar cycloaddition reaction. This approach involvesin situgeneration of azidoacetamide benzothiazole, followed by condensation with terminal alkynes in the presence of CuSO4/Na-ascorbate in aqueous DMSO under both conventional and ultrasound conditions. Some of the designed 1,2,3-triazole conjugates6a-owere recognized for their antimicrobial activity against some bacterial and fungal pathogenic strains.

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