scholarly journals Heparin-based hydrogels with tunable sulfation & degradation for anti-inflammatory small molecule delivery

2016 ◽  
Vol 4 (9) ◽  
pp. 1371-1380 ◽  
Author(s):  
Yifeng Peng ◽  
Liane E. Tellier ◽  
Johnna S. Temenoff
Keyword(s):  
Small Molecule ◽  
Crystal Violet ◽  
Release Kinetics ◽  
Anti Inflammatory ◽  
Kinetics Of

Heparin-based hydrogels enable tunable and linear release kinetics of the anti-inflammatory small molecule, crystal violet.

Delivery of dexamethasone from electrospun PCL–PEO binary fibers and their effects on inflammation regulation

RSC Advances ◽  
2015 ◽  
Vol 5 (43) ◽  
pp. 34166-34172 ◽  
Author(s):  
Yan-Fang Li ◽  
Marina Rubert ◽  
Ying Yu ◽  
Flemming Besenbacher ◽  
Menglin Chen
Keyword(s):  
Gene Expression ◽  
Chemical Composition ◽  
Surface Topography ◽  
Release Kinetics ◽  
Related Gene ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Kinetics Of

Differences in surface topography, chemical composition, wettability and release kinetics of the anti-inflammatory drug dexamethasone among different PCL–PEO fibers collectively affected the regulation of inflammatory related gene expression.

scholarly journals Deposition of Ibuprofen Crystals on Hydroxypropyl Cellulose/Polyacrylamide Gel: Experimental and Mathematic Modeling Releasing

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Claudia Alicia Castillo-Miranda ◽  
Ana Beatriz Morales-Cepeda ◽  
Carlos Fernando Castro-Guerrero ◽  
Homero Salas-Papayanopolos ◽  
Hugo Alberto Velasco-Ocejo ◽  
...  
Keyword(s):  
Release Kinetics ◽  
Hydroxypropyl Cellulose ◽  
Fickian Diffusion ◽  
Solution Temperature ◽  
Phenyl Propionic Acid ◽  
Diffusion Media ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Kinetics Of ◽  
Made In

The crystallization of nonsteroidal anti-inflammatory drug [2-(4-isobutyl-phenyl) propionic acid] ibuprofen (IBP) on a hydroxypropyl cellulose (HPC) and polyacrylamide (PAAm) gel was studied as well as the release kinetics of the drug. The IBP was crystallized on the gel surface of HPC/PAAm. It had a prismatic shape and the growth was made in an aqueous medium; the crystallinity grade of the gels HPC/PAAm and HPC/PAAm-IBU increased to 68% and to 58%, respectively. The release of IBP is performed by two means: by a non-Fickian diffusion process and by relaxation of the chains of the gel; without regard to temperature and the diffusion media, this correlates with the lower critical solution temperature (LCST) of the proposed gel. This polymer matrix provides an option for releasing nonsteroidal anti-inflammatory drugs in a temperature range of 35–39°C. Korsmeyer and Peppas mathematical model was simulated for data releases, statistically significant at 95% confidence level.

Analysis of K+ release kinetics of biomass ash with different pH

2014 ◽  
Vol 22 (2) ◽  
pp. 171-176
Author(s):  
Kan WANG ◽  
Zifang WANG ◽  
Ming GAO ◽  
Yaohua HUANG ◽  
Xiaofei HAN ◽  
...  
Keyword(s):  
Release Kinetics ◽  
Biomass Ash ◽  
Kinetics Of ◽  
K Release

scholarly journals Design and release kinetics of liposomes containing abiraterone acetate for treatment of prostate cancer

2021 ◽  
Vol 2 ◽  
pp. 100077
Author(s):  
Sudipta Das ◽  
Arnab Samanta ◽  
Shouvik Mondal ◽  
Debatri Roy ◽  
Amit Kumar Nayak
Keyword(s):  
Prostate Cancer ◽  
Release Kinetics ◽  
Abiraterone Acetate ◽  
Kinetics Of

scholarly journals Risk Assessment of Agricultural Plastic Films Based on Release Kinetics of Phthalate Acid Esters

2021 ◽  
Vol 55 (6) ◽  
pp. 3676-3685
Author(s):  
Yu Wang ◽  
Fang Wang ◽  
Leilei Xiang ◽  
Chenggang Gu ◽  
Marc Redmile-Gordon ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Release Kinetics ◽  
Plastic Films ◽  
Kinetics Of ◽  
Acid Esters ◽  
Phthalate Acid Esters

scholarly journals Halloysite nanotubes filled with salicylic acid and sodium diclofenac: effects of vacuum pumping on loading and release properties

2021 ◽  
Author(s):  
Lorenzo Lisuzzo ◽  
Giuseppe Cavallaro ◽  
Stefana Milioto ◽  
Giuseppe Lazzara
Keyword(s):  
Salicylic Acid ◽  
Release Kinetics ◽  
Halloysite Nanotubes ◽  
Drug Molecules ◽  
Sodium Diclofenac ◽  
Tunable Release ◽  
Feature Based ◽  
Kinetics Of ◽  
Filling Mechanism

AbstractIn this work, we investigated the effects of the vacuum pumping on both the loading efficiencies and the release kinetics of halloysite nanotubes filled with drug molecules dissolved in ethanol. As model drugs, salicylic acid and sodium diclofenac were selected. For comparison, the loading of the drug molecules was conducted on platy kaolinite to explore the key role of the hollow tubular morphology on the filling mechanism of halloysite. The effects of the pressure conditions used in the loading protocol were interpreted and discussed on the basis of the thermodynamic results provided by Knudsen thermogravimetry, which demonstrated the ethanol confinement inside the halloysite cavity. Several techniques (TEM, FTIR spectroscopy, DLS and $$\zeta$$ ζ -potential experiments) were employed to characterize the drug filled nanoclays. Besides, release kinetics of the drugs were studied and interpreted according to the loading mechanism. This work represents a further step for the development of nanotubular carriers with tunable release feature based on the loading protocol and drug localization into the carrier. Graphic abstract The filling efficiency of halloysite nanotubes is enhanced by the reduction of the pressure conditions used in the loading protocol.

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