Trifluoromethyl-substituted cyclometalated iridiumIII emitters with high photostability for continuous oxygen sensing

2015 ◽  
Vol 3 (31) ◽  
pp. 8010-8017 ◽  
Author(s):  
Chun Liu ◽  
Xin Lv ◽  
Yang Xing ◽  
Jieshan Qiu
Keyword(s):  
Oxygen Sensing ◽  
High Sensitivity ◽  
Quantum Yields ◽  
Quick Response ◽  
Oxidation Potentials ◽  
Enhanced Photostability ◽  
Oxygen Concentrations

New trifluoromethyl-substituted cyclometalated Ir(iii) complexes exhibit high photoluminescence quantum yields, increased oxidation potentials and enhanced photostability. The oxygen sensing films immobilized with Ir(iii) complexes demonstrate quick response and high sensitivity upon changes of oxygen concentrations.

scholarly journals Difluoroboron β-diketonate polylactic acid oxygen nanosensors for intracellular neuronal imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Meng Zhuang ◽  
Suchitra Joshi ◽  
Huayu Sun ◽  
Tamal Batabyal ◽  
Cassandra L. Fraser ◽  
...  
Keyword(s):  
Neuronal Activity ◽  
Oxygen Sensing ◽  
Brain Slices ◽  
Neuronal Cell ◽  
Quantum Yields ◽  
Poly Lactic Acid ◽  
Neuronal Cultures ◽  
Primary Neuronal Cultures ◽  
Non Invasive ◽  
Mitotracker Red

AbstractCritical for metabolism, oxygen plays an essential role in maintaining the structure and function of neurons. Oxygen sensing is important in common neurological disorders such as strokes, seizures, or neonatal hypoxic–ischemic injuries, which result from an imbalance between metabolic demand and oxygen supply. Phosphorescence quenching by oxygen provides a non-invasive optical method to measure oxygen levels within cells and tissues. Difluoroboron β-diketonates are a family of luminophores with high quantum yields and tunable fluorescence and phosphorescence when embedded in certain rigid matrices such as poly (lactic acid) (PLA). Boron nanoparticles (BNPs) can be fabricated from dye-PLA materials for oxygen mapping in a variety of biological milieu. These dual-emissive nanoparticles have oxygen-insensitive fluorescence, oxygen-sensitive phosphorescence, and rigid matrix all in one, enabling real-time ratiometric oxygen sensing at micron-level spatial and millisecond-level temporal resolution. In this study, BNPs are applied in mouse brain slices to investigate oxygen distributions and neuronal activity. The optical properties and physical stability of BNPs in a biologically relevant buffer were stable. Primary neuronal cultures were labeled by BNPs and the mitochondria membrane probe MitoTracker Red FM. BNPs were taken up by neuronal cell bodies, at dendrites, and at synapses, and the localization of BNPs was consistent with that of MitoTracker Red FM. The brain slices were stained with the BNPs, and the BNPs did not significantly affect the electrophysiological properties of neurons. Oxygen maps were generated in living brain slices where oxygen is found to be mostly consumed by mitochondria near synapses. Finally, the BNPs exhibited excellent response when the conditions varied from normoxic to hypoxic and when the neuronal activity was increased by increasing K+ concentration. This work demonstrates the capability of BNPs as a non-invasive tool in oxygen sensing and could provide fundamental insight into neuronal mechanisms and excitability research.

scholarly journals Ratiometric Fluorescent Biosensors for Glucose and Lactate Using an Oxygen-Sensing Membrane

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 208
Author(s):  
Hong Dinh Duong ◽  
Jong Il Rhee
Keyword(s):  
Limit Of Detection ◽  
Oxygen Sensing ◽  
High Sensitivity ◽  
Glucose Sensing ◽  
Oxidation Reactions ◽  
Lactate Oxidase ◽  
Lactate Oxidation ◽  
Detection Range ◽  
Quenching Effect ◽  
Sensing Membrane

In this study, ratiometric fluorescent glucose and lactate biosensors were developed using a ratiometric fluorescent oxygen-sensing membrane immobilized with glucose oxidase (GOD) or lactate oxidase (LOX). Herein, the ratiometric fluorescent oxygen-sensing membrane was fabricated with the ratio of two emission wavelengths of platinum meso-tetra (pentafluorophenyl) porphyrin (PtP) doped in polystyrene particles and coumarin 6 (C6) captured into silica particles. The operation mechanism of the sensing membranes was based on (i) the fluorescence quenching effect of the PtP dye by oxygen molecules, and (ii) the consumption of oxygen levels in the glucose or lactate oxidation reactions under the catalysis of GOD or LOX. The ratiometric fluorescent glucose-sensing membrane showed high sensitivity to glucose in the range of 0.1–2 mM, with a limit of detection (LOD) of 0.031 mM, whereas the ratiometric fluorescent lactate-sensing membrane showed the linear detection range of 0.1–0.8 mM, with an LOD of 0.06 mM. These sensing membranes also showed good selectivity, fast reversibility, and stability over long-term use. They were applied to detect glucose and lactate in artificial human serum, and they provided reliable measurement results.

Specific Detection of Staphylococcus Enterotoxin B in Milk Using Piezoresistive Cantilever Aptasensor

2015 ◽  
Vol 645-646 ◽  
pp. 1298-1302
Author(s):  
Rui Zhao ◽  
Yong Zheng Wen ◽  
Wei Ma ◽  
Jian Cheng Yang ◽  
Xiao Mei Yu
Keyword(s):  
High Sensitivity ◽  
Rapid Response ◽  
Experimental Results ◽  
Quick Response ◽  
Specific Detection ◽  
Detection Range ◽  
Coated Surface ◽  
Enterotoxin B ◽  
Food Commodities ◽  
Staphylococcus Enterotoxin B

In this paper, an aptasensor with high sensitivity and rapid response was developed for the detection of staphylococcus enterotoxin B (SEB) by using thiol-modified piezoresistive cantilever. Thiol-modified aptamers, acting as the functionalized sensing elements, were immobilized on the nanogold-coated surface of the sensing cantilever as agents for detecting SEB. By using the functionalized aptasensors, different concentrations of SEB were detected with a wide detection range of 6-100 ng/mL and a quick response in milk. The experimental results indicated that the cantilever-based aptasensors had sufficient sensitivity for the detection of SEB in real food commodities and might provide an economical platform for on-site detections of different toxicants with the advantages of portability, high sensitivity, and rapid response.

Centrifugal Manometer

1959 ◽  
Vol 81 (3) ◽  
pp. 341-348
Author(s):  
J. F. Kemp
Keyword(s):  
High Sensitivity ◽  
Working Fluid ◽  
Quick Response ◽  
Laboratory Conditions ◽  
Wide Range ◽  
Maximum Range ◽  
Normal Laboratory

The operating principles and mechanical construction of a micromanometer, which utilizes air in lieu of a liquid as working fluid, are described. Some of the noteworthy features of the instrument include its high sensitivity and accuracy, quick response, wide range, and ease of manipulation. Differential pressures of the order of 5 × 10−3 mm water gage can be measured with an error of 1 per cent under normal laboratory conditions. The maximum range of the prototype described is 25 mm water gage, and the corresponding error at this value amounts to about 0.25 per cent.

scholarly journals Supramolecular fluorescence sensor for liquefied petroleum gas

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Yi-Yang Zhan ◽  
Jingyuan Liao ◽  
Mizuho Kajita ◽  
Tatsuo Kojima ◽  
Satoshi Takahashi ◽  
...  
Keyword(s):  
High Selectivity ◽  
High Sensitivity ◽  
Fluorescence Sensor ◽  
Selective Detection ◽  
Quick Response ◽  
Liquefied Petroleum Gas ◽  
Aromatic Rings ◽  
Sensing Systems ◽  
Molecular Container ◽  
Gas Molecules

Abstract Sensing systems of nonpolar gas molecules without functional groups such as natural gas and liquefied petroleum gas (LPG) remain difficult to develop because of lacking selective detection of such molecules over other gas molecules. Here we report a supramolecular fluorescence sensor for LPG using a 2-nm-sized cube-shaped molecular container i.e. a nanocube self-assembled from six molecules of gear-shaped amphiphiles (GSA) in water. The nanocube selectively encapsulates LPG, while it does not bind other gas molecules. Upon encapsulation of LPG in the nanocube, the fluorescence from the nanocube is enhanced by 3.9 times, which is caused by the restricted motion of the aromatic rings of GSA in the nanocube based on aggregation-induced emission. Besides the high selectivity, high sensitivity, quick response, high stability of the nanocube for LPG, and easy preparation of GSA satisfy the requirement for its practical use for an LPG sensor.

scholarly journals Thiophene-forming one-pot synthesis of three thienyl-bridged oligophenothiazines and their electronic properties

2016 ◽  
Vol 12 ◽  
pp. 2055-2064 ◽  
Author(s):  
Dominik Urselmann ◽  
Konstantin Deilhof ◽  
Bernhard Mayer ◽  
Thomas J J Müller
Keyword(s):  
Cyclic Voltammetry ◽  
Helical Structure ◽  
Quantum Yields ◽  
Absorption Bands ◽  
One Pot ◽  
Fluorescence Quantum Yields ◽  
Oxidation Potentials ◽  
Td Dft ◽  
Lower Oxidation ◽  
Stokes Shifts

The pseudo five-component Sonogashira–Glaser cyclization synthesis of symmetrically 2,5-diaryl-substituted thiophenes is excellently suited to access thienyl-bridged oligophenothiazines in a one-pot fashion. Three thienyl-bridged systems were intensively studied by UV–vis and fluorescence spectroscopy as well as by cyclic voltammetry. The oxidation proceeds with lower oxidation potentials and consistently reversible oxidations can be identified. The Stokes shifts are large and substantial fluorescence quantum yields can be measured. Computational chemistry indicates lowest energy conformers with sigmoidal and helical structure, similar to oligophenothiazines. TD-DFT and even semiempirical ZINDO calculations reproduce the trends of longest wavelengths absorption bands and allow the assignment of these transitions to possess largely charge-transfer character from the adjacent phenothiazinyl moieties to the central thienyl unit.

scholarly journals A Ratiometric and Colorimetric Hemicyanine Fluorescent Probe for Detection of SO2 Derivatives and Its Applications in Bioimaging

Molecules ◽  
2019 ◽  
Vol 24 (21) ◽  
pp. 4011 ◽  
Author(s):  
Yan-Hong Qin ◽  
Xiao-Yi Jiang ◽  
Yuan-Fang Que ◽  
Jing-Yi Gu ◽  
Tong Wu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intramolecular Charge Transfer ◽  
Addition Reaction ◽  
High Sensitivity ◽  
Quick Response ◽  
Practical Application ◽  
Michael Addition Reaction ◽  
Real Samples ◽  
Confocal Fluorescence ◽  
The Michael Addition

Based upon the intramolecular charge transfer (ICT) mechanism, a novel ratiometric fluorescent probe EB was developed to detect SO32−/HSO3−. The probe displayed both colorimetric and ratiometric responses toward SO32−/HSO3−. It displayed a quick response (within 60 s), good selectivity and high sensitivity (a detection limit of 28 nM) towards SO32−/HSO3−. The SO32−/HSO3− sensing mechanism was confirmed as the Michael addition reaction by ESI-MS. Moreover, the probe could be applied to measure the level of sulfite in real samples, like sugar and chrysanthemum, and it could also be used to detect SO32−/HSO3− in HepG2 cells through confocal fluorescence microscopy, which proved its practical application in clinical diagnosis.

scholarly journals Complexes trans-Pt(BODIPY)X(PEt3)2: excitation energy-dependent fluorescence and phosphorescence emissions, oxygen sensing and photocatalysis

2016 ◽  
Vol 45 (25) ◽  
pp. 10420-10434 ◽  
Author(s):  
Peter Irmler ◽  
Rainer F. Winter
Keyword(s):  
Excitation Energy ◽  
Oxygen Sensing ◽  
Single Component ◽  
Quantum Yields ◽  
Dual Fluorescence ◽  
Anionic Ligand ◽  
Energy Dependent ◽  
Fluorescence And Phosphorescence

Complexes trans-Pt(BODIPY)X(PEt3)2 exhibit dual fluorescence and phosphorescence emissions, whose intensities are modulated by the anionic ligand X− and the excitation wavelengths. They constitute efficient single-component 3O2 sensors and photocatalysts for aereal photooxidations with quantum yields near unity.

In/Pd-Doped SnO 2 -Based CO Micro-Structure Sensor with High Sensitivity and Quick Response

2009 ◽  
Vol 26 (10) ◽  
pp. 100702 ◽  
Author(s):  
Liu Li ◽  
Zhang Tong ◽  
Li Shou-Chun ◽  
Wang Lian-Yuan ◽  
Fan Hui-Tao ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Quick Response ◽  
Micro Structure ◽  
Structure Sensor
Sign in / Sign up

Export Citation Format

Share Document