Nanofibrous polylactide composite scaffolds with electroactivity and sustained release capacity for tissue engineering

2016 ◽  
Vol 4 (14) ◽  
pp. 2477-2485 ◽  
Author(s):  
Jing Chen ◽  
Juan Ge ◽  
Baolin Guo ◽  
Kun Gao ◽  
Peter X. Ma
Keyword(s):  
Tissue Engineering ◽  
Drug Release ◽  
Sustained Release ◽  
Composite Scaffold ◽  
Myoblast Differentiation ◽  
Sustained Drug Release ◽  
Composite Scaffolds ◽  
Release System ◽  
Release Capacity ◽  
Drug Release System

A conveniently fabricated electroactive nanofibrous composite scaffold serves as a sustained drug release system and promotes myoblast differentiation.

Polymethacrylic acid encapsulated TiO2 nanotubes for sustained drug release and enhanced antibacterial activities

2019 ◽  
Vol 43 (4) ◽  
pp. 1827-1837 ◽  
Author(s):  
Ling Huang ◽  
Jian Chen ◽  
Xiufang Li ◽  
Hui Liu ◽  
Jianbing Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Tio2 Nanotubes ◽  
Antibacterial Activities ◽  
Polymethacrylic Acid ◽  
Sustained Drug Release ◽  
Release System ◽  
Drug Release System

A long-term antibacterial and sustained drug release system was fabricated, in which the TNTs acted as the loading platform of NOR and then encapsulated with PMAA.

Novel gelatin-adriamycin sustained drug release system for intravesical therapy of bladder cancer

2001 ◽  
Vol 21 (2) ◽  
pp. 145-148 ◽  
Author(s):  
Ye Zhangqun ◽  
Chen Jie ◽  
Zhang Xu ◽  
Li Jiagui ◽  
Zhou Siwei ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Drug Release ◽  
Intravesical Therapy ◽  
Sustained Drug Release ◽  
Release System ◽  
Drug Release System

Sustained drug release system using porous structured poly(l-lactic acid) fabricated by solvent dispersion method

2012 ◽  
Vol 20 (1) ◽  
pp. 303-308 ◽  
Author(s):  
Yong-Ha Kim ◽  
Il-Kug Kim ◽  
Tae-Gon Kim ◽  
Jun-Ho Lee ◽  
Young-Kook Lim ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Drug Release ◽  
Dispersion Method ◽  
Sustained Drug Release ◽  
Release System ◽  
Drug Release System

Development and Optimization of Sustained Release Moxifloxacin Hydrochloride Loaded Nanoemulsion for Ophthalmic Drug Delivery: A 32 Factorial Design Approach

2020 ◽  
Vol 12 ◽  
Author(s):  
Sagar R. Pardeshi ◽  
Harshal A. Mistari ◽  
Rakhi S. Jain ◽  
Pankaj R. Pardeshi ◽  
Rahul L. Rajput ◽  
...  
Keyword(s):  
Drug Release ◽  
Sustained Release ◽  
Factorial Design ◽  
Water Solubility ◽  
Tween 80 ◽  
Drug Release Profile ◽  
Sustained Drug Release ◽  
Bacterial Conjunctivitis ◽  
Promising Alternative

Background: Moxifloxacin is a BCS class I drug used in the treatment of bacterial conjunctivitis and keratitis. Despite its high water solubility, it possesses limited bioavailability due to anatomical and physiological constraints associated with the eyes which required multiple administrations to achieve a therapeutic effect. Objective: In order to prolong drug release and to improve antibacterial efficacy for the treatment of bacterial keratitis and conjunctivitis, moxifloxacin loaded nanoemulsion was developed. Methods: The concentration of oil (oleic acid), surfactant (tween 80), and cosurfactant (propylene glycol) were optimized by employing a 3-level 2-factorial design of experiment for the development of nanoemulsion. The developed nanoemulsion was characterized by particle size distribution, viscosity, refractive index, pH, drug content and release, transmission electron microscopy (TEM), and antibacterial study. The compatibility of the drug with the excipients was accessed by Fourier transform infrared spectroscopy (FTIR). Result: The average globule size was found to be 198.20 nm. The TEM study reveals the globules were nearly spherical and are well distributed. In vitro drug release profile for nanoemulsion shown sustained drug release (60.12% at the end of 6 h) compared to drug solution, where complete drug released within 2 h. The antibacterial effectiveness of the drug-loaded nanoemulsion was improved against S. aureus compared with the marketed formulation. Conclusion: The formulated sustained release nanoemulsion could be a promising alternative to eye drop with improved patient compliance by minimizing dosing frequency with improved antibacterial activity.

scholarly journals Anticancer Drug Release System Based on Hollow Silica Nanocarriers Triggered by Tumor Cellular Microenvironments

ACS Omega ◽  
2020 ◽  
Author(s):  
Shaoxin Deng ◽  
Cheng-Xing Cui ◽  
Lingyao Duan ◽  
Linfeng Hu ◽  
Xiaoxun Yang ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
Hollow Silica ◽  
Release System ◽  
Drug Release System ◽  
Cellular Microenvironments

Bacterial meningitis due to infection of a lumbar drug release system in patients with cancer pain

Pain ◽  
1986 ◽  
Vol 25 (1) ◽  
pp. 75-77 ◽  
Author(s):  
P. Schoeffler ◽  
E. Pichard ◽  
R. Ramboatiana ◽  
D. Joyon ◽  
J. P. Haberer
Keyword(s):  
Drug Release ◽  
Bacterial Meningitis ◽  
Cancer Pain ◽  
Release System ◽  
Patients With Cancer ◽  
Drug Release System

Study on ibuprofen/montmorillonite intercalation composites as drug release system

2007 ◽  
Vol 36 (4) ◽  
pp. 297-301 ◽  
Author(s):  
J.P. Zheng ◽  
L. Luan ◽  
H.Y. Wang ◽  
L.F. Xi ◽  
K.D. Yao
Keyword(s):  
Drug Release ◽  
Release System ◽  
Drug Release System

scholarly journals A novel microwave stimulus remote-controlled anticancer drug release system based on Janus TiO2-&mSiO2 nanocarriers

2021 ◽  
Vol 123 ◽  
pp. 111968
Author(s):  
Ye Liu ◽  
Yangying Si ◽  
Mingyu Di ◽  
Dejian Tang ◽  
Li Meng ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
Release System ◽  
Drug Release System
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