Modulation of the structural properties of mesoporous silica nanoparticles to enhance the T1-weighted MR imaging capability

2016 ◽  
Vol 4 (9) ◽  
pp. 1720-1732 ◽  
Author(s):  
Didem Şen Karaman ◽  
Diti Desai ◽  
Jixi Zhang ◽  
Sina Tadayon ◽  
Gözde Unal ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Structural Properties ◽  
Structural Parameters ◽  
Mesoporous Silica Nanoparticles ◽  
Imaging Capability

The contrast enchantment for Gd(iii) incorporated MSN based CAs is investigated by modulating the preparational and structural parameters.

scholarly journals Controlling Particle Size and Structural Properties of Mesoporous Silica Nanoparticles Using the Taguchi Method

2011 ◽  
Vol 115 (27) ◽  
pp. 13158-13165 ◽  
Author(s):  
Ya-Dong Chiang ◽  
Hong-Yuan Lian ◽  
Sin-Yen Leo ◽  
Shy-Guey Wang ◽  
Yusuke Yamauchi ◽  
...  
Keyword(s):  
Particle Size ◽  
Mesoporous Silica ◽  
Taguchi Method ◽  
Silica Nanoparticles ◽  
Structural Properties ◽  
Mesoporous Silica Nanoparticles

ROS-responsive mesoporous silica nanoparticles for MR imaging-guided photodynamically maneuvered chemotherapy

Nanoscale ◽  
2018 ◽  
Vol 10 (20) ◽  
pp. 9616-9627 ◽  
Author(s):  
Vijayakameswara Rao N ◽  
Hwa Seung Han ◽  
Hansang Lee ◽  
Van Quy Nguyen ◽  
Sangmin Jeon ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mr Imaging ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Stimuli Responsive ◽  
Target Sites

Mesoporous silica nanoparticles (MSNs) with stimuli-responsive gatekeepers have been extensively investigated for controlled drug delivery at the target sites.

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

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