Tunable, bioactive protein conjugated hyaluronic acid hydrogel for neural engineering applications

2016 ◽  
Vol 4 (16) ◽  
pp. 2803-2818 ◽  
Author(s):  
Dalia Shendi ◽  
Ana Dede ◽  
Yuan Yin ◽  
Chaoming Wang ◽  
Chandra Valmikinathan ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Click Chemistry ◽  
Michael Addition ◽  
Neural Engineering ◽  
Engineering Applications ◽  
One Step ◽  
Hyaluronic Acid Hydrogel

A one-step Michael addition click chemistry reaction is used to fabricate a bioactive conjugated hyaluronic acid (HA) scaffold for neural engineering applications.

A novel one-step mechanically strengthened hyaluronic acid hydrogel assisted by a small molecular agent

2021 ◽  
Author(s):  
Shan Yu ◽  
Zhiwen Zeng ◽  
Cuiping Guo ◽  
Jiu Jiang ◽  
Dating Pei ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
One Step ◽  
Hyaluronic Acid Hydrogel

Dual-Syringe Reactive Electrospinning of Cross-Linked Hyaluronic Acid Hydrogel Nanofibers for Tissue Engineering Applications

2006 ◽  
Vol 6 (10) ◽  
pp. 811-817 ◽  
Author(s):  
Yuan Ji ◽  
Kaustabh Ghosh ◽  
Bingquan Li ◽  
Jonathan C. Sokolov ◽  
Richard A. F. Clark ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Engineering Applications ◽  
Hyaluronic Acid Hydrogel

Synergistic regenerative effects of functionalized endometrial stromal cells with hyaluronic acid hydrogel in a murine model of uterine damage

2019 ◽  
Vol 89 ◽  
pp. 139-151 ◽  
Author(s):  
Yoon Young Kim ◽  
Kyu-Hyung Park ◽  
Yong Jin Kim ◽  
Moon Suk Kim ◽  
Hung Ching Liu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Murine Model ◽  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Hyaluronic Acid Hydrogel

scholarly journals Three-Dimensional Printable Hydrogel Using a Hyaluronic Acid/Sodium Alginate Bio-Ink

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 794 ◽  
Author(s):  
Su Jeong Lee ◽  
Ji Min Seok ◽  
Jun Hee Lee ◽  
Jaejong Lee ◽  
Wan Doo Kim ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Sodium Alginate ◽  
Three Dimensional ◽  
Fibroblast Cell ◽  
Chemical Crosslinking ◽  
Fibroblast Cell Line ◽  
Engineering Applications ◽  
Encapsulated Cells ◽  
Crosslinking Agents

Bio-ink properties have been extensively studied for use in the three-dimensional (3D) bio-printing process for tissue engineering applications. In this study, we developed a method to synthesize bio-ink using hyaluronic acid (HA) and sodium alginate (SA) without employing the chemical crosslinking agents of HA to 30% (w/v). Furthermore, we evaluated the properties of the obtained bio-inks to gauge their suitability in bio-printing, primarily focusing on their viscosity, printability, and shrinkage properties. Furthermore, the bio-ink encapsulating the cells (NIH3T3 fibroblast cell line) was characterized using a live/dead assay and WST-1 to assess the biocompatibility. It was inferred from the results that the blended hydrogel was successfully printed for all groups with viscosities of 883 Pa∙s (HA, 0% w/v), 1211 Pa∙s (HA, 10% w/v), and 1525 Pa∙s, (HA, 30% w/v) at a 0.1 s−1 shear rate. Their structures exhibited no significant shrinkage after CaCl2 crosslinking and maintained their integrity during the culture periods. The relative proliferation rate of the encapsulated cells in the HA/SA blended bio-ink was 70% higher than the SA-only bio-ink after the fourth day. These results suggest that the 3D printable HA/SA hydrogel could be used as the bio-ink for tissue engineering applications.

An in vitro hyaluronic acid hydrogel based platform to model dormancy in brain metastatic breast cancer cells

2020 ◽  
Vol 107 ◽  
pp. 65-77 ◽  
Author(s):  
Akshay A. Narkhede ◽  
James H. Crenshaw ◽  
David K. Crossman ◽  
Lalita A. Shevde ◽  
Shreyas S. Rao
Keyword(s):  
Breast Cancer ◽  
Hyaluronic Acid ◽  
Metastatic Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Metastatic Breast ◽  
Hyaluronic Acid Hydrogel

Morphological and morphometric analyses of crushed sciatic nerves after application of a purified protein from natural latex and hyaluronic acid hydrogel

2014 ◽  
Vol 32 (5) ◽  
pp. 164-170 ◽  
Author(s):  
Vanessa Cristina Pereira Barreiros ◽  
Fernando José Dias ◽  
Mamie Mizusaki Iyomasa ◽  
Joaquim Coutinho-Netto ◽  
Luiz Gustavo de Sousa ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Morphometric Analyses ◽  
Sciatic Nerves ◽  
Hyaluronic Acid Hydrogel

Self-Crosslinked Hyaluronic Acid Hydrogel (PureRegen Gel Sinus) in Ethmoidectomy: A Randomized, Controlled Trial

2014 ◽  
Vol 151 (1_suppl) ◽  
pp. P127-P127 ◽  
Author(s):  
Keith E. Matheny ◽  
Ewen Tseng ◽  
Kenny B. Carter ◽  
William B. Cobb ◽  
Karen J. Fong
Keyword(s):  
Randomized Controlled Trial ◽  
Hyaluronic Acid ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Hyaluronic Acid Hydrogel
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