Osmo-solidification of all-aqueous emulsion with enhanced preservation of protein activity

2016 ◽  
Vol 4 (7) ◽  
pp. 1213-1218 ◽  
Author(s):  
Qingming Ma ◽  
Yang Song ◽  
Grit Baier ◽  
Christian Holtze ◽  
Ho Cheung Shum
Keyword(s):  
Protein Activity ◽  
Aqueous Emulsion ◽  
Emulsion Droplets

An “osmo-solidification” approach that solidifies all-aqueous emulsion droplets for encapsulating proteins with superior preservation of their activity.

Aqueous Emulsion Droplets Stabilized by Lipid Vesicles as Microcompartments for Biomimetic Mineralization

Langmuir ◽  
2015 ◽  
Vol 31 (41) ◽  
pp. 11329-11338 ◽  
Author(s):  
David N. Cacace ◽  
Andrew T. Rowland ◽  
Joshua J. Stapleton ◽  
Daniel C. Dewey ◽  
Christine D. Keating
Keyword(s):  
Lipid Vesicles ◽  
Biomimetic Mineralization ◽  
Aqueous Emulsion ◽  
Emulsion Droplets

scholarly journals Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Yang Song ◽  
Thomas C. T. Michaels ◽  
Qingming Ma ◽  
Zhou Liu ◽  
Hao Yuan ◽  
...  
Keyword(s):  
Aqueous Emulsion ◽  
Emulsion Droplets

Nanoporous Polymeric Periodic Structures Fabricated by Emulsion-assisted Holographic Patterning

2009 ◽  
Vol 1228 ◽  
Author(s):  
Vincent K.S Hsiao ◽  
Wei-Ting Chang
Keyword(s):  
Periodic Structure ◽  
Periodic Structures ◽  
Polar Phase ◽  
Acrylate Monomer ◽  
Uniform Size ◽  
Aqueous Emulsion ◽  
Emulsion Droplets ◽  
Sodium Dioctyl ◽  
A New Technique ◽  
Average Size

AbstractWe report a new technique of creating a nanoporous polymeric nanostructure by photo-patterning emulsions generated from a formamide (polar phase) and an acrylate-monomer (nonpolar phase). Formamide is a highly polar solvent that forms well dispersed, non-aqueous emulsion droplets within the monomer-containing nonpolar phase before holographic patterning. Photochemically initiated polymerization of the nonpolar phase (acrylate monomer) forces the formation of ordered formamide emulsions defined by the holographic interference. Evaporation of the formamide from the ordered structure yields a periodic structure with high optical reflectivity and a wide reflection bandwidth. The average size and the size distribution of formamide droplets in the photopolymer fluid must be controlled to fabricate a periodic structure with high reflectivity. Furthermore, we found that the addition of sodium dioctyl sulfosuccinate (AOT) surfactant helps to stabilize the formamide emulsion which further facilitates the formation of the ordered nanopores with uniform size.

scholarly journals Cascade communication in disordered networks of enzyme-loaded microdroplets

2021 ◽  
Vol 57 (13) ◽  
pp. 1631-1634
Author(s):  
Marko Pavlovic ◽  
Markus Antonietti ◽  
Lukas Zeininger
Keyword(s):  
Aqueous Emulsion ◽  
Emulsion Droplets ◽  
Disordered Networks

A network of aqueous emulsion droplets that exhibits programmed and directional chemical inter-droplet communication is described.

scholarly journals FOXC1 in cancer development and therapy: deciphering its emerging and divergent roles

2017 ◽  
Vol 9 (12) ◽  
pp. 797-816 ◽  
Author(s):  
Zhi Yang ◽  
Shuai Jiang ◽  
Yicheng Cheng ◽  
Tian Li ◽  
Wei Hu ◽  
...  
Keyword(s):  
Transcriptional Regulator ◽  
Cancer Development ◽  
Protein Activity ◽  
Stem Cell Maintenance ◽  
Cancer Migration ◽  
Forkhead Box ◽  
Pathological Conditions ◽  
Clinical Biomarker ◽  
Abnormal Cell Proliferation ◽  
Cell Maintenance

Forkhead box C1 (FOXC1) is an essential member of the forkhead box transcription factors and has been highlighted as an important transcriptional regulator of crucial proteins associated with a wide variety of carcinomas. FOXC1 regulates tumor-associated genes and is regulated by multiple pathways that control its mRNA expression and protein activity. Aberrant FOXC1 expression is involved in diverse tumorigenic processes, such as abnormal cell proliferation, cancer stem cell maintenance, cancer migration, and angiogenesis. Herein, we review the correlation between the expression of FOXC1 and tumor behaviors. We also summarize the mechanisms of the regulation of FOXC1 expression and activity in physiological and pathological conditions. In particular, we focus on the pathological processes of cancer targeted by FOXC1 and discuss whether FOXC1 is good or detrimental during tumor progression. Moreover, FOXC1 is highlighted as a clinical biomarker for diagnosis or prognosis in various human cancers. The information reviewed here should assist in experimental designs and emphasize the potential of FOXC1 as a therapeutic target for cancer.

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