Tailoring a two-dimensional graphene oxide surface: dual T1 and T2 MRI contrast agent materials

2015 ◽  
Vol 3 (28) ◽  
pp. 5678-5682 ◽  
Author(s):  
Erwin Peng ◽  
Fenghe Wang ◽  
Suhui Tan ◽  
Bingwen Zheng ◽  
Sam Fong Yau Li ◽  
...  

A water-soluble hybrid two-dimensional nanostructured dual T1–T2 MRI contrast agent with fair T1 and T2 nanoparticle separation distance and negligible T1/T2 signal quenching was developed.

2010 ◽  
Vol 2010 (28) ◽  
pp. 4555-4560 ◽  
Author(s):  
Eun Sook Choi ◽  
Ja Young Park ◽  
Myung Ju Baek ◽  
Wenlong Xu ◽  
Krishna Kattel ◽  
...  

2012 ◽  
Vol 85 (1) ◽  
pp. 79-86 ◽  
Author(s):  
Michihiro Ogawa ◽  
Hiromasa Kataoka ◽  
Satoshi Nitahara ◽  
Hiroyuki Fujimoto ◽  
Hiroyuki Aoki ◽  
...  

2015 ◽  
Vol 3 (11) ◽  
pp. 2241-2276 ◽  
Author(s):  
Erwin Peng ◽  
Fenghe Wang ◽  
Jun Min Xue

The development of water-soluble nanostructured magnetic nanocomposites based on hydrophobic magnetic nanoparticle assemblies using an organic functional coating for MRI contrast agent applications was discussed.


RSC Advances ◽  
2015 ◽  
Vol 5 (22) ◽  
pp. 17223-17227 ◽  
Author(s):  
M. Ravichandran ◽  
Goldie Oza ◽  
S. Velumani ◽  
Jose Tapia Ramirez ◽  
Francisco Garcia-Sierra ◽  
...  

A novel, one-step synthesis of one-dimensional cobalt ferrite nanowhiskers (CfW) is reported.


Author(s):  
Yanhui Zhang ◽  
Hailu Zhang ◽  
Dehua Huang ◽  
Bo Tan ◽  
Chengxing Zhang ◽  
...  

Naphthalene is coupled with DOTA via a peptide sequence to yield an amphipathic MRI probe Nap-CFGKTG-DOTA-Gd (Nap-Gd) that can self-assemble into nanofibers. Incubation of NSCs, hMSCs and L929 cells in...


RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86779-86783 ◽  
Author(s):  
M. Borges ◽  
S. Yu ◽  
A. Laromaine ◽  
A. Roig ◽  
S. Suárez-García ◽  
...  

A novel dual T1/T21H-MRI contrast agent based on the encapsulation of super-paramagnetic iron oxide nanoparticles (SPIONs) with an iron coordination polymer is proposed.


2021 ◽  
Vol 6 (12) ◽  
pp. 2862-2868 ◽  
Author(s):  
Somayeh Sadighian ◽  
Nahid Bayat ◽  
Sahar Najaflou ◽  
Mehraneh Kermanian ◽  
Mehrdad Hamidi

2020 ◽  
Vol 13 (10) ◽  
pp. 312
Author(s):  
Huan Yue ◽  
Ji Ae Park ◽  
Son Long Ho ◽  
Mohammad Yaseen Ahmad ◽  
Hyunsil Cha ◽  
...  

Nanoparticles are considered potential candidates for a new class of magnetic resonance imaging (MRI) contrast agents. Negative MRI contrast agents require high magnetic moments. However, if nanoparticles can exclusively induce transverse water proton spin relaxation with negligible induction of longitudinal water proton spin relaxation, they may provide negative contrast MR images despite having low magnetic moments, thus acting as an efficient T2 MRI contrast agent. In this study, carbon-coated paramagnetic dysprosium oxide (DYO@C) nanoparticles (core = DYO = DyxOy; shell = carbon) were synthesized to explore their potential as an efficient T2 MRI contrast agent at 3.0 T MR field. Since the core DYO nanoparticles have an appreciable (but not high) magnetic moment that arises from fast 4f-electrons of Dy(III) (6H15/2), the DYO@C nanoparticles exhibited an appreciable transverse water proton spin relaxivity (r2) with a negligible longitudinal water proton spin relaxivity (r1). Consequently, they acted as a very efficient T2 MRI contrast agent, as proven from negative contrast enhancements seen in the in vivo T2 MR images.


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