Polymer nanoparticles with electrostatically loaded multicargo for combined cancer phototherapy

2015 ◽  
Vol 3 (15) ◽  
pp. 3001-3010 ◽  
Author(s):  
Aurore Fraix ◽  
Ilse Manet ◽  
Marco Ballestri ◽  
Andrea Guerrini ◽  
Paolo Dambruoso ◽  
...  

Fluorescent biocompatible polymeric nanoparticles entangling two photoactive chromophores induce amplified cancer cell death due to the simultaneous photogeneration of1O2and NO.

Nanoscale ◽  
2019 ◽  
Vol 11 (42) ◽  
pp. 20261-20273 ◽  
Author(s):  
William J. McDaid ◽  
Michelle K. Greene ◽  
Michael C. Johnston ◽  
Ellen Pollheimer ◽  
Peter Smyth ◽  
...  

The use of CTX as a targeting agent for camptothecin-loaded polymeric nanoparticles directed against KRAS mutant CTX-resistant cancer cells was investigated. CTX increased CPT internalisation into cancer cells resulting in elevated cancer cell death.


2015 ◽  
Vol 12 (8) ◽  
pp. 2869-2878 ◽  
Author(s):  
Yao-Xin Lin ◽  
Yu-Juan Gao ◽  
Yi Wang ◽  
Zeng-Ying Qiao ◽  
Gang Fan ◽  
...  

2016 ◽  
Vol 23 (15) ◽  
pp. 1513-1527 ◽  
Author(s):  
Magdalena Gorska ◽  
Alicja Kuban-Jankowska ◽  
Jaroslaw Slawek ◽  
Michal Wozniak

2019 ◽  
Vol 234 (11) ◽  
pp. 20648-20661 ◽  
Author(s):  
Zhen Yu ◽  
Ze Yu ◽  
ZhenBao Chen ◽  
Lin Yang ◽  
MingJun Ma ◽  
...  

2021 ◽  
Author(s):  
Wooram Park ◽  
Seok-Jo Kim ◽  
Paul Cheresh ◽  
Jeanho Yun ◽  
Byeongdu Lee ◽  
...  

Mitochondria are crucial regulators of the intrinsic pathway of cancer cell death. The high sensitivity of cancer cells to mitochondrial dysfunction offers opportunities for emerging targets in cancer therapy. Herein,...


2013 ◽  
Vol 24 (8) ◽  
pp. 1414-1414 ◽  
Author(s):  
Megan A. Mackey ◽  
Farhat Saira ◽  
Mahmoud A. Mahmoud ◽  
Mostafa A. El-Sayed

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