scholarly journals Characterization of the crosslinking kinetics of multi-arm poly(ethylene glycol) hydrogels formed via Michael-type addition

Soft Matter ◽  
2016 ◽  
Vol 12 (7) ◽  
pp. 2076-2085 ◽  
Author(s):  
Jiwon Kim ◽  
Yen P. Kong ◽  
Steven M. Niedzielski ◽  
Rahul K. Singh ◽  
Andrew J. Putnam ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Michael Type Addition ◽  
Poly Ethylene ◽  
Kinetics Of

scholarly journals Regulating the Homogeneity of Thiol-Maleimide Michael-Type Addition-Based Hydrogels Using Amino Biomolecules

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 206
Author(s):  
Yu Guo ◽  
Jie Gu ◽  
Yuxin Jiang ◽  
Yanyan Zhou ◽  
Zhenshu Zhu ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Reaction Rate ◽  
Side Chain ◽  
Short Peptides ◽  
Poly Ethylene Glycol ◽  
Fast Reaction ◽  
Gelation Kinetics ◽  
Michael Type Addition ◽  
Poly Ethylene ◽  
Kinetics Of

Poly(ethylene glycol) (PEG)-based synthetic hydrogels based on Michael-type addition reaction have been widely used for cell culture and tissue engineering. However, recent studies showed that these types of hydrogels were not homogenous as expected since micro domains generated due to the fast reaction kinetics. Here, we demonstrated a new kind of method to prepare homogenous poly(ethylene glycol) hydrogels based on Michael-type addition using the side chain amine-contained short peptides. By introducing such a kind of short peptides, the homogeneity of crosslinking and mechanical property of the hydrogels has been also significantly enhanced. The compressive mechanical and recovery properties of the homogeneous hydrogels prepared in the presence of side chain amine-contained short peptides were more reliable than those of inhomogeneous hydrogels while the excellent biocompatibility remained unchanged. Furthermore, the reaction rate and gelation kinetics of maleimide- and thiol-terminated PEG were proved to be significantly slowed down in the presence of the side chain amine-contained short peptides, thus leading to the improved homogeneity of the hydrogels. We anticipate that this new method can be widely applied to hydrogel preparation and modification based on Michael-type addition gelation.

scholarly journals Non-Isothermal Crystallization Kinetics of Poly(Ethylene Glycol)–Poly(l-Lactide) Diblock Copolymer and Poly(Ethylene Glycol) Homopolymer via Fast-Scan Chip-Calorimeter

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1156
Author(s):  
Dejia Chen ◽  
Lisha Lei ◽  
Meishuai Zou ◽  
Xiaodong Li
Keyword(s):  
Ethylene Glycol ◽  
Heterogeneous Nucleation ◽  
Isothermal Crystallization ◽  
Crystallization Process ◽  
Poly Ethylene Glycol ◽  
Ozawa Method ◽  
Isothermal Crystallization Kinetics ◽  
Fast Cooling ◽  
Poly Ethylene ◽  
Kinetics Of

The non-isothermal crystallization kinetics of double-crystallizable poly(ethylene glycol)–poly(l-lactide) diblock copolymer (PEG-PLLA) and poly(ethylene glycol) homopolymer (PEG) were studied using the fast cooling rate provided by a Fast-Scan Chip-Calorimeter (FSC). The experimental data were analyzed by the Ozawa method and the Kissinger equation. Additionally, the total crystallization rate was represented by crystallization half time t1/2. The Ozawa method is a perfect success because secondary crystallization is inhibited by using fast cooling rate. The first crystallized PLLA block provides nucleation sites for the crystallization of PEG block and thus promotes the crystallization of the PEG block, which can be regarded as heterogeneous nucleation to a certain extent, while the method of the PEG block and PLLA block crystallized together corresponds to a one-dimensional growth, which reflects that there is a certain separation between the crystallization regions of the PLLA block and PEG block. Although crystallization of the PLLA block provides heterogeneous nucleation conditions for PEG block to a certain extent, it does not shorten the time of the whole crystallization process because of the complexity of the whole crystallization process including nucleation and growth.

scholarly journals Evaluation of the Ultraviolet-Curing Kinetics of Ultraviolet-Polymerized Oligomers Cured Using Poly (Ethylene Glycol) Dimethacrylate

Coatings ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 99 ◽  
Author(s):  
Ji-Won Park ◽  
Jong-Gyu Lee ◽  
Gyu-Seong Shim ◽  
Hyun-Joong Kim ◽  
Young-Kwan Kim ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Curing Kinetics ◽  
Ethylene Glycol Dimethacrylate ◽  
Glycol Dimethacrylate ◽  
Poly Ethylene Glycol ◽  
Ultraviolet Curing ◽  
Poly Ethylene ◽  
Kinetics Of
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