scholarly journals The functional role of the structure of the dioxo-isobacteriochlorin in the catalytic site of cytochrome cd1 for the reduction of nitrite

2016 ◽  
Vol 7 (4) ◽  
pp. 2896-2906 ◽  
Author(s):  
Hiroshi Fujii ◽  
Daisuke Yamaki ◽  
Takashi Ogura ◽  
Masahiko Hada
Keyword(s):  
Functional Role ◽  
Catalytic Site ◽  
Nitrite Reduction ◽  
Model Complexes ◽  
Synthetic Model ◽  
Cytochrome Cd1

We studied the functional role of the unique heme d1 in the catalytic nitrite reduction using synthetic model complexes.

New insights into the activity of Pseudomonas aeruginosa cd1 nitrite reductase

2008 ◽  
Vol 36 (6) ◽  
pp. 1155-1159 ◽  
Author(s):  
Serena Rinaldo ◽  
Alessandro Arcovito ◽  
Giorgio Giardina ◽  
Nicoletta Castiglione ◽  
Maurizio Brunori ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pseudomonas Aeruginosa ◽  
Nitrite Reductase ◽  
Nitrite Reduction ◽  
Nitrite Reductases ◽  
Cytochrome Cd1 ◽  
Haem Iron ◽  
Shed Light ◽  
Denitrification Process

The cytochrome cd1 nitrite reductases are enzymes that catalyse the reduction of nitrite to nitric oxide (NO) in the bacterial energy conversion denitrification process. These enzymes contain two different redox centres: one covalently bound c-haem, which is reduced by external donors, and one peculiar d1-haem, where catalysis occurs. In the present paper, we summarize the current understanding of the reaction of nitrite reduction in the light of the most recent results on the enzyme from Pseudomonas aeruginosa and discuss the differences between enzymes from different organisms. We have evidence that release of NO from the ferrous d1-haem occurs rapidly enough to be fully compatible with the turnover, in contrast with previous hypotheses, and that the substrate nitrite is able to displace NO from the d1-haem iron. These results shed light on the mechanistic details of the activity of cd1 nitrite reductases and on the biological role of the d1-haem, whose presence in this class of enzymes has to date been unexplained.

Functional role of DNRA and nitrite reduction in a pristine south Chilean Nothofagus forest

2008 ◽  
Vol 90 (3) ◽  
pp. 243-258 ◽  
Author(s):  
T. Rütting ◽  
D. Huygens ◽  
C. Müller ◽  
O. Van Cleemput ◽  
R. Godoy ◽  
...  
Keyword(s):  
Functional Role ◽  
Nitrite Reduction ◽  
Nothofagus Forest

scholarly journals M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue

Authorea ◽  
2020 ◽  
Author(s):  
Raphael Dutoit ◽  
Nathalie Brandt ◽  
Tom Van Gompel ◽  
Dany Van Elder ◽  
Jeroen Van Dyck ◽  
...  
Keyword(s):  
Functional Role ◽  
Catalytic Site ◽  
Aspartate Residue

Author response for "M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue"

2020 ◽  
Author(s):  
Raphaël Dutoit ◽  
Nathalie Brandt ◽  
Tom Van Gompel ◽  
Dany Van Elder ◽  
Jeroen Van Dyck ◽  
...  
Keyword(s):  
Functional Role ◽  
Catalytic Site ◽  
Author Response ◽  
Aspartate Residue

scholarly journals M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue

2020 ◽  
Vol 88 (12) ◽  
pp. 1639-1647
Author(s):  
Raphaël Dutoit ◽  
Nathalie Brandt ◽  
Tom Van Gompel ◽  
Dany Van Elder ◽  
Jeroen Van Dyck ◽  
...  
Keyword(s):  
Functional Role ◽  
Catalytic Site ◽  
Aspartate Residue
Sign in / Sign up

Export Citation Format

Share Document