scholarly journals Selective glycoprotein detection through covalent templating and allosteric click-imprinting

2015 ◽  
Vol 6 (9) ◽  
pp. 5114-5119 ◽  
Author(s):  
Alexander Stephenson-Brown ◽  
Aaron L. Acton ◽  
Jon A. Preece ◽  
John S. Fossey ◽  
Paula M. Mendes
Keyword(s):  
Click Chemistry ◽  
Boronic Acids ◽  
The Self ◽  
Binding Affinities ◽  
Bottom Up ◽  
High Binding ◽  
Self Assembled ◽  
Reversible Covalent ◽  
Covalent Interactions

A hierarchical bottom-up route exploiting reversible covalent interactions with boronic acids and so-called click chemistry for selective glycoprotein detection is described. The self-assembled and imprinted surfaces confer high binding affinities, nanomolar sensitivity, exceptional glycoprotein specificity and selectivity.

Azobenzene-functionalized graphene nanoribbons: bottom-up synthesis, photoisomerization behaviour and self-assembled structures

2020 ◽  
Vol 8 (31) ◽  
pp. 10837-10843
Author(s):  
Zhichun Shangguan ◽  
Chunyang Yu ◽  
Chen Li ◽  
Xianhui Huang ◽  
Yiyong Mai ◽  
...  
Keyword(s):  
Self Assembly ◽  
Graphene Nanoribbons ◽  
The Self ◽  
Functionalized Graphene ◽  
Bottom Up ◽  
Self Assembled ◽  
Azobenzene Groups

We show the strategy of introducing azobenzene groups into graphene nanoribbons (GNRs), which not only endows GNRs with fast photo-responsiveness but also induces the self-assembly of the GNRs into ultra-long nanowires.

scholarly journals Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

2014 ◽  
Vol 50 (86) ◽  
pp. 13157-13160 ◽  
Author(s):  
D. J. Nieves ◽  
N. S. Azmi ◽  
R. Xu ◽  
R. Lévy ◽  
E. A. Yates ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Growth Factor ◽  
Click Chemistry ◽  
Fibroblast Growth Factor ◽  
Michael Addition ◽  
The Self ◽  
Fibroblast Growth Factor 2 ◽  
Fibroblast Growth ◽  
Self Assembled Monolayer ◽  
Self Assembled

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

The self-assembled monolayer of saccharide via click chemistry: Formation and protein recognition

2008 ◽  
Vol 516 (9) ◽  
pp. 2443-2449 ◽  
Author(s):  
Yoshiko Miura ◽  
Takahiro Yamauchi ◽  
Hajime Sato ◽  
Tomohiro Fukuda
Keyword(s):  
Click Chemistry ◽  
The Self ◽  
Protein Recognition ◽  
Self Assembled Monolayer ◽  
Self Assembled

scholarly journals Preparation of Composite Materials from Self-Assembled Chitin Nanofibers

Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3548
Author(s):  
Jun-ichi Kadokawa
Keyword(s):  
Composite Materials ◽  
Short Review ◽  
The Self ◽  
Material Source ◽  
Bottom Up ◽  
Nanostructured Composite ◽  
Self Assembling ◽  
Self Assembled ◽  
Polymeric Substrates ◽  
Chitin Nanofibers

Although chitin is a representative abundant polysaccharide, it is mostly unutilized as a material source because of its poor solubility and processability. Certain specific properties, such as biodegradability, biocompatibility, and renewability, make nanofibrillation an efficient approach for providing chitin-based functional nanomaterials. The composition of nanochitins with other polymeric components has been efficiently conducted at the nanoscale to fabricate nanostructured composite materials. Disentanglement of chitin microfibrils in natural sources upon the top-down approach and regeneration from the chitin solutions/gels with appropriate media, such as hexafluoro-2-propanol, LiCl/N, N-dimethylacetamide, and ionic liquids, have, according to the self-assembling bottom-up process, been representatively conducted to fabricate nanochitins. Compared with the former approach, the latter one has emerged only in the last one-and-a-half decade. This short review article presents the preparation of composite materials from the self-assembled chitin nanofibers combined with other polymeric substrates through regenerative processes based on the bottom-up approach.

Nanoscale Self-Assembly Using Ion and Electron Beam Techniques: A Rapid Review

MRS Advances ◽  
2020 ◽  
Vol 5 (64) ◽  
pp. 3507-3520
Author(s):  
Chunhui Dai ◽  
Kriti Agarwal ◽  
Jeong-Hyun Cho
Keyword(s):  
Electron Beam ◽  
Self Assembly ◽  
Ion Beam ◽  
Three Dimensional ◽  
The Self ◽  
Stress Generation ◽  
Rapid Review ◽  
High Yield ◽  
3D Nanostructures ◽  
Self Assembled

AbstractNanoscale self-assembly, as a technique to transform two-dimensional (2D) planar patterns into three-dimensional (3D) nanoscale architectures, has achieved tremendous success in the past decade. However, an assembly process at nanoscale is easily affected by small unavoidable variations in sample conditions and reaction environment, resulting in a low yield. Recently, in-situ monitored self-assembly based on ion and electron irradiation has stood out as a promising candidate to overcome this limitation. The usage of ion and electron beam allows stress generation and real-time observation simultaneously, which significantly enhances the controllability of self-assembly. This enables the realization of various complex 3D nanostructures with a high yield. The additional dimension of the self-assembled 3D nanostructures opens the possibility to explore novel properties that cannot be demonstrated in 2D planar patterns. Here, we present a rapid review on the recent achievements and challenges in nanoscale self-assembly using electron and ion beam techniques, followed by a discussion of the novel optical properties achieved in the self-assembled 3D nanostructures.

Bottom-up Evolution from Disks to High-Genus Polymersomes

2018 ◽  
Author(s):  
Claudia Contini ◽  
Russell Pearson ◽  
Linge Wang ◽  
Lea Messager ◽  
Jens Gaitzsch ◽  
...  
Keyword(s):  
Self Assembly ◽  
The Self ◽  
Amphiphilic Copolymers ◽  
Chain Entanglement ◽  
Bottom Up ◽  
New Approach ◽  
High Genus ◽  
Transmission Electron ◽  
Minimal Radius ◽  
Stop Flow

<div><div><div><p>We report the design of polymersomes using a bottom-up approach where the self-assembly of amphiphilic copolymers poly(2-(methacryloyloxy) ethyl phosphorylcholine)–poly(2-(diisopropylamino) ethyl methacrylate) (PMPC-PDPA) into membranes is tuned using pH and temperature. We study this process in detail using transmission electron microscopy (TEM), nuclear magnetic resonance (NMR) spectroscopy, dynamic light scattering (DLS), and stop-flow ab- sorbance disclosing the molecular and supramolecular anatomy of each structure observed. We report a clear evolution from disk micelles to vesicle to high-genus vesicles where each passage is controlled by pH switch or temperature. We show that the process can be rationalised adapting membrane physics theories disclosing important scaling principles that allow the estimation of the vesiculation minimal radius as well as chain entanglement and coupling. This allows us to propose a new approach to generate nanoscale vesicles with genus from 0 to 70 which have been very elusive and difficult to control so far.</p></div></div></div>

Bottom-up Evolution from Disks to High-Genus Polymersomes

2018 ◽  
Author(s):  
Claudia Contini ◽  
Russell Pearson ◽  
Linge Wang ◽  
Lea Messager ◽  
Jens Gaitzsch ◽  
...  
Keyword(s):  
Self Assembly ◽  
The Self ◽  
Amphiphilic Copolymers ◽  
Chain Entanglement ◽  
Bottom Up ◽  
New Approach ◽  
High Genus ◽  
Transmission Electron ◽  
Minimal Radius ◽  
Stop Flow

<div><div><div><p>We report the design of polymersomes using a bottom-up approach where the self-assembly of amphiphilic copolymers poly(2-(methacryloyloxy) ethyl phosphorylcholine)–poly(2-(diisopropylamino) ethyl methacrylate) (PMPC-PDPA) into membranes is tuned using pH and temperature. We study this process in detail using transmission electron microscopy (TEM), nuclear magnetic resonance (NMR) spectroscopy, dynamic light scattering (DLS), and stop-flow ab- sorbance disclosing the molecular and supramolecular anatomy of each structure observed. We report a clear evolution from disk micelles to vesicle to high-genus vesicles where each passage is controlled by pH switch or temperature. We show that the process can be rationalised adapting membrane physics theories disclosing important scaling principles that allow the estimation of the vesiculation minimal radius as well as chain entanglement and coupling. This allows us to propose a new approach to generate nanoscale vesicles with genus from 0 to 70 which have been very elusive and difficult to control so far.</p></div></div></div>

scholarly journals Nano- and Micropatterning on Optical Fibers by Bottom-Up Approach: The Importance of Being Ordered

2021 ◽  
Vol 11 (7) ◽  
pp. 3254
Author(s):  
Marco Pisco ◽  
Francesco Galeotti
Keyword(s):  
Optical Fiber ◽  
Optical Fibers ◽  
Self Assembly ◽  
Ordered Structures ◽  
Bottom Up ◽  
Photonic Structures ◽  
Fiber Technology ◽  
Optical Fiber Probes ◽  
Fiber Probes ◽  
Self Assembled

The realization of advanced optical fiber probes demands the integration of materials and structures on optical fibers with micro- and nanoscale definition. Although researchers often choose complex nanofabrication tools to implement their designs, the migration from proof-of-principle devices to mass production lab-on-fiber devices requires the development of sustainable and reliable technology for cost-effective production. To make it possible, continuous efforts are devoted to applying bottom-up nanofabrication based on self-assembly to decorate the optical fiber with highly ordered photonic structures. The main challenges still pertain to “order” attainment and the limited number of implementable geometries. In this review, we try to shed light on the importance of self-assembled ordered patterns for lab-on-fiber technology. After a brief presentation of the light manipulation possibilities concerned with ordered structures, and of the new prospects offered by aperiodically ordered structures, we briefly recall how the bottom-up approach can be applied to create ordered patterns on the optical fiber. Then, we present un-attempted methodologies, which can enlarge the set of achievable structures, and can potentially improve the yielding rate in finely ordered self-assembled optical fiber probes by eliminating undesired defects and increasing the order by post-processing treatments. Finally, we discuss the available tools to quantify the degree of order in the obtained photonic structures, by suggesting the use of key performance figures of merit in order to systematically evaluate to what extent the pattern is really “ordered”. We hope such a collection of articles and discussion herein could inspire new directions and hint at best practices to fully exploit the benefits inherent to self-organization phenomena leading to ordered systems.

Tetranuclear copper(ii) cubane complexes derived from self-assembled 1,3-dimethyl-5-(o-phenolate-azo)-6-aminouracil: structures, non-covalent interactions and magnetic property

2021 ◽  
Vol 45 (5) ◽  
pp. 2742-2753
Author(s):  
Nishithendu Bikash Nandi ◽  
Atanu Purkayastha ◽  
Shaktibrata Roy ◽  
Julia Kłak ◽  
Rakesh Ganguly ◽  
...  
Keyword(s):  
Magnetic Property ◽  
Exchange Coupling ◽  
Antiferromagnetic Exchange ◽  
Non Covalent Interactions ◽  
Cubane Cluster ◽  
Self Assembled ◽  
Covalent Interactions

A new doubly opened 4 + 2 Cu4O4 cubane cluster exhibits strong antiferromagnetic exchange coupling with J1 = −110.1 cm−1, and J2 = −27.1 cm−1.

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