scholarly journals Accurate molecular weight determination of small molecules via DOSY-NMR by using external calibration curves with normalized diffusion coefficients

2015 ◽  
Vol 6 (6) ◽  
pp. 3354-3364 ◽  
Author(s):  
Roman Neufeld ◽  
Dietmar Stalke
Keyword(s):  
Molecular Weight ◽  
Small Molecules ◽  
Calibration Curve ◽  
Diffusion Coefficients ◽  
Molecular Weight Determination ◽  
External Calibration ◽  
Calibration Curves ◽  
External Calibration Curve ◽  
Dosy Nmr

We describe a novel development of MW-determination by using an external calibration curve approach with normalized diffusion coefficients.

scholarly journals Application of 1H DOSY NMR in Measurement of Polystyrene Molecular Weights

2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Nguyen Hoai Nam ◽  
Nguyen Huu Tho ◽  
Nguyen Minh Ngoc ◽  
Pham Quang Trung
Keyword(s):  
Molecular Weight ◽  
Diffusion Coefficient ◽  
Hydrodynamic Radius ◽  
Gel Permeation Chromatography ◽  
Resonance Spectroscopy ◽  
Solvent Interaction ◽  
Molecular Weights ◽  
External Calibration Curve ◽  
Dosy Nmr

In this work, we studied the applicability of diffusion ordered nuclear magnetic resonance spectroscopy (DOSY NMR) as an alternative method in determination of polystyrene molecular weight. DOSY NMR spectroscopy allows measuring the diffusion coefficient of molecule which directly depend on hydrodynamic radius and so on, average molar mass in weight (Mw). By using commercial polystyrene (PS) standards, an external calibration curve was established. Based on the excellent linear correlation between diffusion coefficient (logD) and molecular weight (logM), the molecular weight of polystyrene can be predicted using the following equation . The validation was done by comparing with the Mw value obtained by gel permeation chromatography within less than 5% deviation. From the diffusion coefficient, some property of polystyrene in solution, such as Flory coefficient and polymer-solvent interaction, were also studied. The Flory coefficient confirmed that chloroform is a good solvent for PS.

Molecular Weight Determination of Component Polypeptides of Glutenin after Fractionation by Gel Filtration

1975 ◽  
Vol 39 (8) ◽  
pp. 1527-1531
Author(s):  
Zen-ichiro Hamauzu ◽  
Yukio Kamazuka ◽  
Hirokazu Kanazawa ◽  
Daizo Yonezawa
Keyword(s):  
Molecular Weight ◽  
Gel Filtration ◽  
Molecular Weight Determination
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