An efficient and convenient protocol for the synthesis of tetracyclic isoindolo[1,2-a]quinazoline derivatives

RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36599-36601 ◽  
Author(s):  
M. V. Madhubabu ◽  
R. Shankar ◽  
Satish. S. More ◽  
Mandava V. Basaveswara Rao ◽  
U. K. Syam Kumar ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Bond Formation ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives ◽  
Bond Formation Reactions

A convenient and one-pot synthesis of tetracyclic isoindolo [1,2-a]quinazoline derivatives via Lewis acid mediated sequential C–N bond formation reactions is reported.

scholarly journals An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization

Synlett ◽  
2018 ◽  
Vol 29 (13) ◽  
pp. 1717-1722 ◽  
Author(s):  
Manjula Alla ◽  
Gal Potuganti ◽  
Divakar Indukuri
Keyword(s):  
Bond Formation ◽  
Nitrogen Sources ◽  
Oxidative Cyclization ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Aerobic Conditions ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields.

Nano-cuprous oxide catalyzed one-pot synthesis of a carbazole-based STAT3 inhibitor: a facile approach via intramolecular C–N bond formation reactions

RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36775-36785 ◽  
Author(s):  
C. P. Baburajeev ◽  
Chakrabhavi Dhananjaya Mohan ◽  
Govindagouda S. Patil ◽  
Shobith Rangappa ◽  
Vijay Pandey ◽  
...  
Keyword(s):  
Cuprous Oxide ◽  
Inhibitory Activity ◽  
Bond Formation ◽  
One Pot ◽  
Carbazole Derivatives ◽  
One Pot Synthesis ◽  
The One ◽  
New Compounds ◽  
Bond Formation Reactions

In this study, we report the one-pot synthesis of substituted carbazole derivatives using nano cuprous oxide as a catalyst and demonstrated the STAT3 inhibitory activity of new compounds.

Lewis Acid Catalyzed Dual Bond Formation: One-Pot Synthesis of Indenes

2018 ◽  
Vol 3 (1) ◽  
pp. 289-293 ◽  
Author(s):  
Pedireddi Niharika ◽  
Gedu Satyanarayana
Keyword(s):  
Lewis Acid ◽  
Bond Formation ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acid Catalyzed

Synthesis of pyrazolo[1,5-c]quinazoline derivatives through the copper-catalyzed domino reaction of o-alkenyl aromatic isocyanides with diazo compounds

2020 ◽  
Vol 56 (55) ◽  
pp. 7665-7668 ◽  
Author(s):  
Lu Liu ◽  
Lei Li ◽  
Shukuan Mao ◽  
Xin Wang ◽  
Ming-Dong Zhou ◽  
...  
Keyword(s):  
Diazo Compounds ◽  
Domino Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

Various o-alkenyl aromatic isocyanides were prepared from readily available reactants for their double annulation with diazo compounds for a one-pot synthesis of pyrazolo[1,5-c]quinazolines under mild reaction conditions.

Promiscuous lipase catalyzed a new P-C bond formation: Green and efficient protocol for one-pot synthesis of α-aminophosphonates

2017 ◽  
Vol 28 (6) ◽  
pp. e21408 ◽  
Author(s):  
Samia Guezane-Lakoud ◽  
Martial Toffano ◽  
Louisa Aribi-Zouioueche
Keyword(s):  
Bond Formation ◽  
One Pot ◽  
One Pot Synthesis

A heavy metal- and oxidant-free, one-pot synthesis of pyridines and fused pyridines based on a Lewis acid-catalyzed multicomponent reaction

2014 ◽  
Vol 50 (82) ◽  
pp. 12270-12272 ◽  
Author(s):  
V. P. Alex Raja ◽  
Giammarco Tenti ◽  
Subbu Perumal ◽  
J. Carlos Menéndez
Keyword(s):  
Heavy Metal ◽  
Lewis Acid ◽  
Multicomponent Reaction ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acid Catalyzed

Pyridines and fused pyridines are accessible by a combination of a Lewis acid-catalyzed multicomponent reaction and aromatization involving loss of a 2-furylmethyl chain.

ChemInform Abstract: BF3·OEt2-Mediated One Pot Synthesis of 10-Indolyldibenzo[b,f]azepine Derivatives via Tandem Ring Expansion and C-C Bond Formation.

ChemInform ◽  
2015 ◽  
Vol 46 (13) ◽  
pp. no-no
Author(s):  
Trimurtulu Kotipalli ◽  
Donala Janreddy ◽  
Veerababurao Kavala ◽  
Chun-Wei Kuo ◽  
Ting-Shen Kuo ◽  
...  
Keyword(s):  
Bond Formation ◽  
Ring Expansion ◽  
One Pot ◽  
One Pot Synthesis
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