Synthesis and characterization of bioreducible heparin-polyethyleneimine nanogels: application as imaging-guided photosensitizer delivery vehicle in photodynamic therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (18) ◽  
pp. 14692-14704 ◽  
Author(s):  
Tilahun Ayane Debele ◽  
Shewaye Lakew Mekuria ◽  
Shuian-Yin Lin ◽  
Hsieh-Chih Tsai
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Synthesis And Characterization ◽  
Delivery Vehicle ◽  
Blue Fluorescence ◽  
Image Guided ◽  
Image Guided Drug Delivery ◽  
Bright Blue Fluorescence ◽  
Bright Blue

HPC nanogels possess bright blue fluorescence which eliminates the use of additional probing agents in image-guided drug delivery. The results showed that disulfide crosslinked HPC nanogels are promising vehicles for stimulated photosensitizer delivery in advanced PDT.

Synthesis and characterization of a porphyrin-crown ether conjugate as a potential intermediate for drug delivery application

2020 ◽  
pp. A-G
Author(s):  
Maher Fathalla
Keyword(s):  
Mass Spectrometry ◽  
Drug Delivery ◽  
High Resolution Mass Spectrometry ◽  
Mesoporous Silica Nanoparticles ◽  
Synthesis And Characterization ◽  
Delivery Vehicle ◽  
Potential Applications ◽  
Resolution Mass ◽  
C Nmr

The development of synthetic strategies for functional building units plays a central role in supramolecular chemistry. Both porphyrin and crown ethers have attracted the attention of researchers worldwide owing to their unique properties. It is envisioned that the integration of the two molecules will result in hybrid materials with potential applications in many fields. In the present study, a new porphyrin derivative 3 appended with four 18-crown-6 (18C6) ether moieties was synthesized through the Suzuki-Miyaura coupling of boronic ester porphyrin 1 and 4-bromobenzo-18-crown-6 2 in 80% yield. Porphyrin 3 was fully characterized by 1H/[Formula: see text]C NMR spectroscopy and high resolution mass spectrometry. The tendency of the 18C6 to form host-guest complexes with ammonium cations was exploited to assemble cation responsive hybrid material of porphyrin 3 and ammonium immobilized mesoporous silica nanoparticles (MSNs). Furthermore, the potential application of the 3/MSNs conjugate as a cation-responsive drug delivery vehicle was investigated in solution by UV-vis and fluorescence spectroscopies.

A Multifunctional Theranostic Platform Based on Phthalocyanine-Loaded Dendrimer for Image-Guided Drug Delivery and Photodynamic Therapy

2013 ◽  
Vol 10 (10) ◽  
pp. 3946-3958 ◽  
Author(s):  
Olena Taratula ◽  
Canan Schumann ◽  
Michael A. Naleway ◽  
Addison J. Pang ◽  
Kaitlyn J. Chon ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Image Guided ◽  
Image Guided Drug Delivery

Synthesis and characterization of thiolated carboxymethyl chitosan-graft-cyclodextrin nanoparticles as a drug delivery vehicle for albendazole

2013 ◽  
Vol 24 (8) ◽  
pp. 1939-1949 ◽  
Author(s):  
Ghazaleh Alamdarnejad ◽  
Alireza Sharif ◽  
Shahrouz Taranejoo ◽  
Mohsen Janmaleki ◽  
Mohammad Reza Kalaee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Carboxymethyl Chitosan ◽  
Synthesis And Characterization ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

Preparation and Characterization of SrAl2O4: Eu2+, Dy3+ Luminescent Nanofibers

2014 ◽  
Vol 496-500 ◽  
pp. 13-16 ◽  
Author(s):  
Jia Lin Liu ◽  
Kai Yan Zhang ◽  
Juo Luo ◽  
Yu Ping Chang
Keyword(s):  
Blue Shift ◽  
Blue Fluorescence ◽  
Electrospinning Technique ◽  
Reducing Atmosphere ◽  
Characteristic Emission ◽  
Ultraviolet Ray ◽  
Ion Characteristic ◽  
Bright Blue Fluorescence ◽  
Bright Blue

PVP/[Sr (NO3)2+Al (NO3)3+Eu (NO3)3+Dy (NO3)3] composite nanofibres were prepared by electrospinning technique. SrAl2O4:Eu2+, Dy3+ luminescent nanofibers were synthesized by calcination under a reducing atmosphere at 1100°C. The luminescent nanofibers were characterized by XRD, SEM, FTIR, TG, fluorescence spectrophotometer, respectively. The experimental results showed that the products are with monoclinic SrAl2O4 crystal structure, the diameter of nanofibers is about 100nm and the size is uniformly distributed. The luminescent nanofibers emit bright blue fluorescence of 470nm in wavelength of Eu2+ ion characteristic emission under the excitation of 365nm in wavelength of ultraviolet ray. The position of emission peak exhibit blue shift in some degree compared with that of bulk SrAl2O4:Eu2+, Dy3+.

scholarly journals Synthesis and characterization of novel protein nanodots as drug delivery carriers with an enhanced biological efficacy of melatonin in breast cancer cells

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9076-9085
Author(s):  
Kanchan Yadav ◽  
Megha Das ◽  
Nurul Hassan ◽  
Archana Mishra ◽  
Jayeeta Lahiri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Cells ◽  
Live Cell Imaging ◽  
Biomedical Applications ◽  
Breast Cancer Cells ◽  
Cell Imaging ◽  
Synthesis And Characterization ◽  
Novel Protein

A novel nanodot-using protein has been synthesized for the live cell imaging and drug delivery of melatonin in breast cancer cells. Its unique properties hold potential for various biomedical applications in the field of bioimaging and drug delivery.

Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications

2020 ◽  
Vol 21 (8) ◽  
pp. 3332-3341 ◽  
Author(s):  
Richard M. England ◽  
Jennifer I. Moss ◽  
Anders Gunnarsson ◽  
Jeremy S. Parker ◽  
Marianne B. Ashford
Keyword(s):  
Drug Delivery ◽  
Star Polymers ◽  
Synthesis And Characterization ◽  
Drug Delivery Applications
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