Fabrication and characterization of PCL/CaCO3 electrospun composite membrane for bone repair

RSC Advances ◽  
2016 ◽  
Vol 6 (13) ◽  
pp. 10641-10649 ◽  
Author(s):  
Zhinan Cao ◽  
Dandan Wang ◽  
Lingwei Lyu ◽  
Yihong Gong ◽  
Yan Li
Keyword(s):  
Osteogenic Differentiation ◽  
Hierarchical Structure ◽  
Composite Membrane ◽  
Bone Repair ◽  
Composite Membranes ◽  
Differentiation Potential ◽  
The Hierarchical Structure ◽  
Fabrication And Characterization

CaCO3/casein microspheres were entrapped in PCL membranes using electrospinning to mimic the hierarchical structure of ECM in bone. The composite membranes showed enhanced biomineralization property, proliferation and osteogenic differentiation potential of HMSCs.

Fabrication and characterization of a PTFE-reinforced integral composite membrane for self-humidifying PEMFC

2007 ◽  
Vol 165 (2) ◽  
pp. 786-792 ◽  
Author(s):  
Yu Zhang ◽  
Huamin Zhang ◽  
Xiaobing Zhu ◽  
Liu Gang ◽  
Cheng Bi ◽  
...  
Keyword(s):  
Composite Membrane ◽  
Fabrication And Characterization

Modeling the hierarchical structure of secondhand clothing buying behavior antecedents of millennials

2020 ◽  
Vol 15 (4) ◽  
pp. 1679-1708 ◽  
Author(s):  
Maria Esther Medalla ◽  
Kafferine Yamagishi ◽  
Ann Myril Tiu ◽  
Reciel Ann Tanaid ◽  
Dharyll Prince Mariscal Abellana ◽  
...  
Keyword(s):  
Hierarchical Structure ◽  
Current Literature ◽  
Design Methodology ◽  
Structural Modeling ◽  
Buying Behavior ◽  
Theoretical Frameworks ◽  
Content Type ◽  
The Hierarchical Structure ◽  
Holistic Analysis

Purpose Due to the growing dominance of the millennials in the secondhand clothing (SHC) market, it is crucial to understand the dynamics of their SHC buying behavior. Despite such significance, it has yet to be explored in the current literature. To address such a gap, this paper aims to explore the antecedents of the SHC buying behavior of millennials. Design/methodology/approach A purposive survey is conducted to establish relationships between the antecedents. As such, the interrelationships of the antecedents are modeled using the interpretative structural modeling (ISM) approach. Findings Results reveal that SHC antecedents exhibit several characteristics depending upon their characterization of being driving, dependence, linkage and autonomous variables. Originality/value This work pioneers the identification of SHC buying behavior antecedents specifically for the millennial market, as well as in the provision of a holistic analysis of the complex contextual relationships of these antecedents. The findings of this work provide insights that are crucial to the extant literature in developing theoretical frameworks and paradigms that help in understanding the dynamics of the SHC buying behavior. Moreover, such results are beneficial to marketing managers and practitioners in innovating their strategies to capture the millennial market better.

scholarly journals CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression

2020 ◽  
Vol 28 (1) ◽  
pp. 283-302
Author(s):  
Dandan Zhang ◽  
Ni Ni ◽  
Yuyao Wang ◽  
Zhimin Tang ◽  
Huiqin Gao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Regenerative Medicine ◽  
Osteogenic Differentiation ◽  
Progenitor Cell ◽  
Bone Repair ◽  
Circular Rnas ◽  
Mineral Density ◽  
Differentiation Potential ◽  
Integrin Α5

AbstractAdipose-derived mesenchymal stem cells (ADSCs) are promising candidate for regenerative medicine to repair non-healing bone defects due to their high and easy availability. However, the limited osteogenic differentiation potential greatly hinders the clinical application of ADSCs in bone repair. Accumulating evidences demonstrate that circular RNAs (circRNAs) are involved in stem/progenitor cell fate determination, but their specific role in stem/progenitor cell osteogenesis, remains mostly undescribed. Here, we show that circRNA-vgll3 originating from the vgll3 locus markedly enhances osteogenic differentiation of ADSCs; nevertheless, silencing of circRNA-vgll3 dramatically attenuates ADSC osteogenesis. Furthermore, we validate that circRNA-vgll3 functions in ADSC osteogenesis through a circRNA-vgll3/miR-326-5p/integrin α5 (Itga5) pathway. Itga5 promotes ADSC osteogenic differentiation and miR-326-5p suppresses Itga5 translation. CircRNA-vgll3 directly sequesters miR-326-5p in the cytoplasm and inhibits its activity to promote osteogenic differentiation. Moreover, the therapeutic potential of circRNA-vgll3-modified ADSCs with calcium phosphate cement (CPC) scaffolds was systematically evaluated in a critical-sized defect model in rats. Our results demonstrate that circRNA-vgll3 markedly enhances new bone formation with upregulated bone mineral density, bone volume/tissue volume, trabeculae number, and increased new bone generation. This study reveals the important role of circRNA-vgll3 during new bone biogenesis. Thus, circRNA-vgll3 engineered ADSCs may be effective potential therapeutic targets for bone regenerative medicine.

Preparation of Novel Polyaniline and Phosphoric Acid Doped Sulfonated Polybenzimidazole Composite Membranes for Fuel Cells

2014 ◽  
Vol 584-586 ◽  
pp. 1669-1672
Author(s):  
Yong Ming Zhang ◽  
Jing Zou ◽  
Lei Wang ◽  
Han Chen ◽  
Jie Si
Keyword(s):  
High Temperature ◽  
Phosphoric Acid ◽  
Composite Membrane ◽  
Proton Exchange Membrane ◽  
Composite Membranes ◽  
Proton Exchange ◽  
Synthesis And Characterization ◽  
Sulfonated Polybenzimidazole ◽  
Exchange Membrane

Polyaniline (PANI) and phosphoric acid (PA) doped sulfonated polybenzimidazole (SPBI) composite membrane was prepared for application in high-temperature proton exchange membrane (PEMFC) without the need of humidification. The synthesis and characterization of targed composite membrane were introduced in this paper.

scholarly journals Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone

Biomaterials ◽  
2011 ◽  
Vol 32 (34) ◽  
pp. 8892-8904 ◽  
Author(s):  
Holly D. Barth ◽  
Elizabeth A. Zimmermann ◽  
Eric Schaible ◽  
Simon Y. Tang ◽  
Tamara Alliston ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Cortical Bone ◽  
Hierarchical Structure ◽  
X Ray ◽  
Human Cortical Bone ◽  
The Hierarchical Structure
Sign in / Sign up

Export Citation Format

Share Document