A pH sensitive co-delivery system of siRNA and doxorubicin for pulmonary administration to B16F10 metastatic lung cancer

RSC Advances ◽  
2015 ◽  
Vol 5 (125) ◽  
pp. 103380-103385 ◽  
Author(s):  
Caina Xu ◽  
Huayu Tian ◽  
Hai Sun ◽  
Zixue Jiao ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Delivery System ◽  
Ph Sensitive ◽  
Metastatic Lung Cancer ◽  
Pulmonary Administration ◽  
Metastatic Lung

Doxorubicin was conjugated to PEI by hydrazone bonds to form a pH sensitive conjugate (PEI-HZ-DOX). The complex particles (PEI-HZ-DOX/Bcl2) could be co-delivered to cancer cells by pulmonary administration. ​

The suppression of metastatic lung cancer by pulmonary administration of polymer nanoparticles for co-delivery of doxorubicin and Survivin siRNA

2016 ◽  
Vol 4 (11) ◽  
pp. 1646-1654 ◽  
Author(s):  
Caina Xu ◽  
Huayu Tian ◽  
Ping Wang ◽  
Yanbing Wang ◽  
Xuesi Chen
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Polymer Nanoparticles ◽  
Metastatic Lung Cancer ◽  
Pulmonary Administration ◽  
Metastatic Lung

DOX and siRNA were sprayed into trachea, bronchi and alveoli, and were co-delivered to cancer cells.

Pulmonary Codelivery of Doxorubicin and siRNA by pH-Sensitive Nanoparticles for Therapy of Metastatic Lung Cancer

Small ◽  
2015 ◽  
Vol 11 (34) ◽  
pp. 4321-4333 ◽  
Author(s):  
Caina Xu ◽  
Ping Wang ◽  
Jingpeng Zhang ◽  
Huayu Tian ◽  
Kinam Park ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ph Sensitive ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

scholarly journals In vivoselection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion

Oncotarget ◽  
2015 ◽  
Vol 6 (26) ◽  
pp. 22905-22917 ◽  
Author(s):  
Xiaopan Cai ◽  
Jian Luo ◽  
Xinghai Yang ◽  
Huayun Deng ◽  
Jishen Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

pH-sensitive tangeretin-ZnO quantum dots exert apoptotic and anti-metastatic effects in metastatic lung cancer cell line

2018 ◽  
Vol 92 ◽  
pp. 477-488 ◽  
Author(s):  
A. Roshini ◽  
Srikanth Jagadeesan ◽  
Lakshmi Arivazhagan ◽  
Young-Jae Cho ◽  
Jong-Hwan Lim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Ph Sensitive ◽  
Lung Cancer Cell Line ◽  
Metastatic Lung Cancer ◽  
Lung Cancer Cell ◽  
Metastatic Lung

scholarly journals Conditionally reprogrammed cells (CRC) methodology does not allow thein vitroexpansion of patient-derived primary and metastatic lung cancer cells

2018 ◽  
Vol 143 (1) ◽  
pp. 88-99 ◽  
Author(s):  
Giovanni Sette ◽  
Valentina Salvati ◽  
Ilenia Giordani ◽  
Emanuela Pilozzi ◽  
Denise Quacquarini ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

scholarly journals Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981

2016 ◽  
Vol 8 (6) ◽  
pp. 1217-1226 ◽  
Author(s):  
Jiacong You ◽  
Rui Chang ◽  
Bin Liu ◽  
Lingling Zu ◽  
Qinghua Zhou
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

Characterization of cultured primary/metastatic lung cancer cells obtained by percutaneous puncture

2017 ◽  
Author(s):  
Adriana Rojas Moreno ◽  
Alejandra Cañas Arboleda ◽  
Angelica Herreño ◽  
Maria Jose Fernandez ◽  
Juan Andres Mejia ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Metastatic Lung Cancer ◽  
Percutaneous Puncture ◽  
Metastatic Lung

scholarly journals ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells

Cell Reports ◽  
2021 ◽  
Vol 37 (4) ◽  
pp. 109880
Author(s):  
Jillian Hattaway Luttman ◽  
Jacob P. Hoj ◽  
Kevin H. Lin ◽  
Jiaxing Lin ◽  
Jing Jin Gu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Metastatic Lung Cancer ◽  
Allosteric Inhibitors ◽  
Metastatic Lung
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