Curcumin loaded on pullulan acetate nanoparticles protects the liver from damage induced by DEN

RSC Advances ◽  
2016 ◽  
Vol 6 (7) ◽  
pp. 5599-5610 ◽  
Author(s):  
Moorthy Ganeshkumar ◽  
Thangavel Ponrasu ◽  
Muthaiya Kannappan Subamekala ◽  
Murthy Janani ◽  
Lonchin Suguna
Keyword(s):  
Pullulan Acetate

Curcumin loaded nanoparticles protect liver from damage induced by DEN.

Pullulan acetate nanoparticles prepared by solvent diffusion method for epirubicin chemotherapy

2009 ◽  
Vol 71 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Hui-zhu Zhang ◽  
Fu-ping Gao ◽  
Ling-rong Liu ◽  
Xue-min Li ◽  
Zhi-min Zhou ◽  
...  
Keyword(s):  
Diffusion Method ◽  
Solvent Diffusion ◽  
Pullulan Acetate

Preparation of folate-modified pullulan acetate nanoparticles for tumor-targeted drug delivery

Drug Delivery ◽  
2009 ◽  
Vol 17 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Hui-zhu Zhang ◽  
Xue-min Li ◽  
Fu-ping Gao ◽  
Ling-rong Liu ◽  
Zhi-min Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Targeted Drug ◽  
Pullulan Acetate

scholarly journals Pullulan acetate coated magnetite nanoparticles for hyper-thermia: Preparation, characterization and in vitro experiments

Nano Research ◽  
2010 ◽  
Vol 3 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Fuping Gao ◽  
Yuanyuan Cai ◽  
Jing Zhou ◽  
Xiaoxue Xie ◽  
Weiwei Ouyang ◽  
...  
Keyword(s):  
Magnetite Nanoparticles ◽  
In Vitro Experiments ◽  
Pullulan Acetate

Cytotoxicity and Cellular Internalization of Epirubicin-Loaded Folate-Conjugated Pullulan Acetate Nanoparticles in Cancer Cells

2016 ◽  
Vol 8 (11) ◽  
pp. 2029-2036 ◽  
Author(s):  
Hongli Chen ◽  
Yajing Jia ◽  
Wenbin Nan ◽  
Hongbo Tang ◽  
Zhimin Zhou ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cellular Internalization ◽  
Pullulan Acetate

scholarly journals Controlled Release of Ursodeoxycholic Acid from Pullulan Acetate Nanoparticles to Modulate Glutamate-Induced Excitotoxicity in PC-12 Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Kwang Sik Yu ◽  
Jun Young Oh ◽  
Min Cheol Kim ◽  
Seong Hee Kang ◽  
Nam Seob Lee ◽  
...  
Keyword(s):  
Ursodeoxycholic Acid ◽  
Neuronal Damage ◽  
Annexin V ◽  
In Vitro Study ◽  
Poly Vinyl Alcohol ◽  
Neuroprotective Effects ◽  
Transmission Electron ◽  
Pullulan Acetate ◽  
Related Proteins

The neuroprotective effects of the ursodeoxycholic acid- (UDCA-) loaded pullulan acetate (PA) (UDCA-PA) nanospheres stabilized by poly(vinyl alcohol) (PVA) were identified by in vitro study. The UDCA-PA nanospheres were constructed by nanoemulsion process. The UDCA-PA nanospheres were analyzed using Fourier transform-infrared spectroscopy (FT-IR) and transmission electron microscopy (TEM). Then, the UDCA-PA nanospheres were used to treat PC-12 neuronal cells, which were formerly triggered by glutamate-induced excitotoxicity. As a result, the cells treated with the UDCA-PA nanospheres showed higher survival rate against glutamate-induced excitotoxicity. Furthermore, the UDCA-PA nanospheres decreased immunoreactivity of Annexin V, a membrane marker for apoptotic cells, in PC-12 with glutamate-induced injury. Particularly, the UDCA-PA nanospheres decreased the level of apoptosis-related proteins such as caspase-3. Taken together, the UDCA-PA nanospheres increased neuroprotective effects against glutamate-induced neuronal damage via inhibition of apoptosis at low concentration.

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