The use of polymer-supported Candida antarctica lipase B to achieve the entropically-driven ring-opening polymerization of macrocyclic bile acid derivatives via transesterification: selectivity of the reactions and the structures of the polymers produced

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93057-93066 ◽  
Author(s):  
Philip Hodge ◽  
Abdel B. Chakiri
Keyword(s):  
Bile Acid ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Macrocyclic Lactones ◽  
Lipase B ◽  
Bile Acid Derivatives ◽  
Polymer Supported

ED-ROPs of macrocyclic lactones by transesterifications catalyzed by CALB are further explored and predictions of the product structures made.

Ring-opening polymerization of bile acid macrocycles by Candida antarctica lipase B

2013 ◽  
Vol 4 (16) ◽  
pp. 4312 ◽  
Author(s):  
Satu Strandman ◽  
I-Huang Tsai ◽  
Robert Lortie ◽  
X. X. Zhu
Keyword(s):  
Bile Acid ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B

Rational redesign of Candida antarctica lipase B for the ring opening polymerization of d,d-lactide

2011 ◽  
Vol 47 (26) ◽  
pp. 7392 ◽  
Author(s):  
Mohamad Takwa ◽  
Marianne Wittrup Larsen ◽  
Karl Hult ◽  
Mats Martinelle
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B

Pore-expanded SBA-15 for the immobilization of a recombinant Candida antarctica lipase B: Application in esterification and hydrolysis as model reactions

2018 ◽  
Vol 129 ◽  
pp. 12-24 ◽  
Author(s):  
Nathalia Saraiva Rios ◽  
Maisa Pessoa Pinheiro ◽  
Magno Luís Bezerra Lima ◽  
Denise Maria Guimarães Freire ◽  
Ivanildo José da Silva ◽  
...  
Keyword(s):  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Model Reactions

Structural effects on chemo- and enantioselectivity of Candida antarctica lipase B - Resolution of β-amino esters

2002 ◽  
Vol 80 (6) ◽  
pp. 565-570 ◽  
Author(s):  
Szilvia Gedey ◽  
Arto Liljeblad ◽  
László Lázár ◽  
Ferenc Fülöp ◽  
Liisa T Kanerva
Keyword(s):  
Key Words ◽  
Candida Antarctica ◽  
Diisopropyl Ether ◽  
The Other ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Structural Effects ◽  
Lipase B ◽  
Amino Esters ◽  
Catalyzed Reactions

The Candida antarctica lipase B-catalyzed reactions of five β-amino esters with neat butyl butanoate and with 2,2,2-trifluoroethyl butanoate in diisopropyl ether were studied, as were the reactions of the same β-amino esters and their N-butanamides with neat butanol. The possibility for sequential resolution, where the amino and ester functions of the substrate both react with an achiral butanoate, became less likely with increasing size of the substrate from ethyl 3-aminobutanoate (1a) to pentanoate (1b) or larger. On the other hand, the alcoholyses of N-acylated β-amino esters successfully proceeded in butanol with E > 100. Gram-scale resolution of the N-butanoylated 1a was performed to demonstrate the usefulness of the method. Key words: lipase, interesterification, acylation, alcoholysis, resolution, β-amino esters.

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