An efficient one-pot decarboxylative aromatization of tetrahydro-β-carbolines by using N-chlorosuccinimide: total synthesis of norharmane, harmane and eudistomins
A mild one-pot synthesis of β-carbolines from their tetrahydro-β-carboline acids has been developed via decorboxylative aromatization using N-chlorosuccinimide (NCS).