Effects of spermine on the morphology, digestive enzyme activities, and antioxidant status of jejunum in suckling rats

RSC Advances ◽  
2015 ◽  
Vol 5 (93) ◽  
pp. 76607-76614 ◽  
Author(s):  
Wei Cao ◽  
Guangmang Liu ◽  
Tingting Fang ◽  
Xianjian Wu ◽  
Gang Jia ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Nucleic Acids ◽  
Ion Channel ◽  
Enzyme Activities ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Cellular Component ◽  
Suckling Rats ◽  
Gut Epithelium ◽  
Digestive Enzyme Activities

Spermine is a ubiquitous cellular component that plays vital roles in the maintenance of nucleic acids, regulation of kinase activities, protein synthesis, control of ion channel activities and renewal of the gut epithelium.

scholarly journals Effects of spermine on ileal physical barrier, antioxidant capacity, metabolic profile and large intestinal bacteria in piglets

RSC Advances ◽  
2020 ◽  
Vol 10 (45) ◽  
pp. 26709-26716
Author(s):  
Guangmang Liu ◽  
Weiwei Mo ◽  
Wei Cao ◽  
Xianjian Wu ◽  
Gang Jia ◽  
...  
Keyword(s):  
Small Intestine ◽  
Oxidative Damage ◽  
Antioxidant Capacity ◽  
Enzyme Activities ◽  
Metabolic Profile ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Intestinal Bacteria ◽  
Physical Barrier ◽  
Digestive Enzyme Activities

Spermine, a polyamine, exerts important roles in alleviating oxidative damage, improving immunity, increasing antioxidant status and digestive enzyme activities, and promoting the development of small intestine.

scholarly journals The Impact of Wheat Bran on the Morphology and Physiology of the Gastrointestinal Tract in Broiler Chickens

Animals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1831
Author(s):  
Qinghui Shang ◽  
Di Wu ◽  
Hansuo Liu ◽  
Shad Mahfuz ◽  
Xiangshu Piao
Keyword(s):  
Gastrointestinal Tract ◽  
Wheat Bran ◽  
Enzyme Activities ◽  
Broiler Chickens ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Nutrient Digestibility ◽  
Jejunal Mucosa ◽  
Villus Height ◽  
Digestive Enzyme Activities

There is increasing evidence showing that moderate amounts of insoluble dietary fiber can improve nutrient utilization by positively influencing the physiology of the gastrointestinal tract. The present study was conducted to investigate the effects of wheat bran as a source of insoluble fiber on nutrient digestibility, serum antioxidant status, gastrointestinal development, digestive enzyme activities and intestinal morphology in broiler chickens. A total of 96 one-day-old male Arbor Acre broiler chickens were assigned to two treatments with six replicate cages per treatment and eight birds per replicate for 42 d. Dietary treatments consisted of the control group (CON, control diet) and wheat bran group (WB, 30 g/kg wheat bran). Inclusion of WB increased (p < 0.05) the digestibility of dry matter, organic matter, gross energy and crude protein on Day 42. Birds fed WB had lower (p < 0.05) serum total cholesterol concentration on Day 21, and lower (p < 0.05) serum concentrations of low-density lipoprotein, total cholesterol and total triglyceride on Day 42. Inclusion of WB increased (p < 0.05) serum glutathione peroxidase activity on Day 21 and superoxide dismutase activity on Day 42, but tended (p = 0.07) to decrease serum malondialdehyde concentration on Day 21, and significantly decreased (p < 0.05) serum malondialdehyde concentration on Day 42. Birds fed WB had a greater (p < 0.05) relative weight of gizzard on both Day 21 and 42. Inclusion of WB increased (p < 0.05) activities of amylase and trypsin in pancreas and jejunal mucosa on Day 21, and increased (p < 0.05) amylase activity in pancreas and jejunal mucosa. Birds fed WB had greater (p < 0.05) villus height and villus height to crypt depth ratio in jejunum and ileum on Day 42. In conclusion, supplementation of 30 g/kg WB enhanced nutrient digestibility by improving antioxidant status, gizzard development, intestinal digestive enzyme activities and morphology of broilers.

scholarly journals Effects of Hydrolysable Tannins as Zinc Oxide Substitutes on Antioxidant Status, Immune Function, Intestinal Morphology, and Digestive Enzyme Activities in Weaned Piglets

Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 757 ◽  
Author(s):  
Hansuo Liu ◽  
Jiangxu Hu ◽  
Shad Mahfuz ◽  
Xiangshu Piao
Keyword(s):  
Enzyme Activities ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Phase 1 ◽  
Intestinal Morphology ◽  
Phase 2 ◽  
Weaned Piglets ◽  
Villus Height ◽  
Hydrolysable Tannins ◽  
Digestive Enzyme Activities

Zinc oxide (ZnO) has negative environmental effects and bioavailability in weaned piglets. Thus, finding safe and effective ZnO substitutes to improve intestinal health and to prevent diarrhea of weaned piglets is urgently required. Therefore, this experiment was conducted to evaluate the effects of hydrolysable tannins (HT), ZnO and HT versus ZnO on growth performance, antioxidant status, serum immunity, intestinal morphology, and digestive enzyme activities in weaned pigs. A total of 144 piglets (28 d-old, initial body weight 7.81 ± 0.99 kg) were assigned to 4 treatments with 6 replicates of 6 piglets each. The experiment lasted 28 d (d 1 to 14 as for phase 1 and d 15 to 28 as for phase 2). The dietary treatments include a corn-soybean meal basal diet (CON); ZnO diet (CON + 2000 mg/kg ZnO in phase 1 and 137.5 mg/kg ZnO in phase 2); HT diet (CON + 1000 mg/kg HT in the overall period (d 1 to 28); HT + ZnO diet (CON + 2000 mg/kg ZnO + 1000 mg/kg HT in phase 1, and 137.5 mg/kg ZnO + 1000 mg/kg HT in phase 2). In phase 1, the incidence of diarrhea was lower (p < 0.05) in the HT + ZnO group than CON. Serum catalase (CAT) and glutathione peroxidase (GSH-Px) were increased (p < 0.01) and malondialdehyde (MDA) was decreased (p < 0.01) in the HT + ZnO group than CON. Compared with CON, immunoglobulin M (IgM), immunoglobulin A (IgA) were increased (p < 0.05) in the HT + ZnO group. In phase 2, both HT and HT + ZnO had a trend to improve (p < 0.10) daily gain. The concentration of total antioxidant capacity (T-AOC) and IgM in serum was higher (p < 0.01) in HT compared with CON. Supplementation of HT improved (p < 0.01) GSH-Px activities in ileum mucosa than the ZnO group. Compared with CON, trypsin, lipase activities, and villus height of jejunum were improved (p < 0.05) in HT and HT + ZnO. The ratio of villus height to crypt depth in the jejunum was improved (p < 0.05) in the HT + ZnO group and which also was increased (p < 0.05) in ileum in the HT group compared with CON. Propionic acid, butyric acid, and acetic acid concentrations in the colon were increased (p < 0.05) in the HT group than CON. Overall, HT + ZnO treatments could be used to replace ZnO for reducing diarrhea and improving antioxidant capacity, immunity, and digestive enzyme activities in weaned piglets.

scholarly journals Effect of Dietary Supplementation of Inulin on Growth Performance, Digestion Enzyme Activities and Antioxidant Status of Rainbow Trout (Oncorhynchus mykiss)

2019 ◽  
Vol 7 (9) ◽  
pp. 1344 ◽  
Author(s):  
Arzu Özlüer Hunt ◽  
Mükereem Çetinkaya ◽  
Ferbal Özkan Yılmaz ◽  
Metin Yıldırım ◽  
Mehmet Berkoz ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Growth Performance ◽  
Enzyme Activities ◽  
Antioxidant Status ◽  
Digestive Enzyme ◽  
Conversion Ratio ◽  
Control Group ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Final Weight ◽  
Digestive Enzyme Activities

The present study investigated the effects of the prebiotic inulin on the growth parameters, digestive enzyme activities and antioxidant status of rainbow trout (Oncorhynchus mykiss). After acclimation, fish (34±0.22 g; n = 135) were assigned into 9 tanks (15 fish per tank) and triplicate groups were fed a control diet (G-0) or diets containing 1% (G-1) or 2% (G-2) inulin. At the end of the trial (8 weeks), growth factors (final weight, weight gain, specific growth rate (SGR), food conversion ratio (FCR), protein efficiency ratio (PER), Economic conversion ratio (ECR), digestive enzyme activities (pepsin, trypsin, amylase and lipase) and antioxidant status superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) level of liver tissue were assessed. At the end of the study highest survival rate was observed in the fish fed with 1% G-1 inulin group. Similarly, digestive enzyme activities were significantly higher dietary G-1 group. Subsequently, elevated growth performance (final weight, SGR and FCR) was observed in trout fed with 1% compared to the control group. The effect of the dietary inulin on digestion was partly observed by assaying the activity of pepsin, intestinal amylase, trypsin and lipase. Apart from pepsin activity, results indicated that dietary supplementation of inulin is beneficial and may also have differential effects upon digestive enzyme activities. Antioxidant enzyme activity of SOD and CAT in liver tissue was generally higher in the supplemented inulin diets than in the control and significantly higher in the 1% inulin group. A significant decrease in MDA level of tissue was observed in all inulin supplemented groups when compared to the control group. These results indicate that inulin be considered as a beneficial dietary supplement for growth performance, digestive enzyme activities and antioxidant status of rainbow trout.

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