Graphene-reinforced poly(vinyl alcohol) electrospun fibers as building blocks for high performance nanocomposites

RSC Advances ◽  
2015 ◽  
Vol 5 (103) ◽  
pp. 85009-85018 ◽  
Author(s):  
Sajjad Ghobadi ◽  
Sina Sadighikia ◽  
Melih Papila ◽  
Fevzi Çakmak Cebeci ◽  
Selmiye Alkan Gürsel
Keyword(s):  
Polymer Matrix ◽  
Vinyl Alcohol ◽  
High Performance ◽  
Building Blocks ◽  
Poly Vinyl Alcohol ◽  
Electrospun Fibers ◽  
Matrix Solution ◽  
High Level

Graphene-containing fibrous structures with a high level of affinity towards a polymer matrix solution have been proved to be promising for high performance macroscopic nanocomposite reinforcement purposes.

Co-electrospun-electrosprayed PVA/folic acid nanofibers for transdermal drug delivery: Preparation, characterization, and in vitro cytocompatibility

2021 ◽  
pp. 152808372199718
Author(s):  
Fatma Nur Parın ◽  
Çiğdem İnci Aydemir ◽  
Gökçe Taner ◽  
Kenan Yıldırım
Keyword(s):  
Folic Acid ◽  
Polymer Matrix ◽  
Vinyl Alcohol ◽  
Matrix Material ◽  
In Vitro Study ◽  
Poly Vinyl Alcohol ◽  
Electrospun Fibers ◽  
Pva Gel ◽  
Fast Release

In this study, hydrophilic based bioactive nanofibers were produced via an electrospinning and electrospraying simultaneous process. Poly(vinyl alcohol) (PVA), poly(vinyl alcohol)-gelatin (PVA-Gel), and poly(vinyl alcohol)-alginate (PVA-Alg) polymers were used as the matrix material and folic acid (FA) particles were dispersed simultaneously on the surface of the nanofibers. The morphology of the nanofibers (NFs) was uniform and confirmed by scanning electron microscopy. Thermal behavior, chemical structure of the composite nanofibers were investigated by thermogravimetric analysis, and Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy which showed that no chemical bonding between vitamin and polymers. A fast release of FA-loaded electrospun fibers was carried out by UV-Vis in vitro study within the 8 hour-period in artificial sweat solutions (pH 5.44). The obtained PVA/FA, PVA-Gel/FA, and PVA-Alg/FA fibers released 49.6%, 69.55%, and 50.88% of the sprayed FA in 8 h, indicating the influence of polymer matrix and polymer-drug interactions, on its release from the polymer matrix. Moreover, biocompatibility of all developed novel NFs was assessed by two different cytotoxicity tests, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and neutral red uptake (NRU) assay in L929 (mouse fibroblasts) cell lines. In all cases, it is concluded that these new electrospun fibers had fast-release of the vitamin and the hybrid process is suitable for transdermal patch applications, especially for skin-care products. The results of cytocompatibility assays on L929 reveal that all prepared NFs have no or slight cell toxicity. PVA and PVA-Gel with/without FA nanofibers seems more biocompatible than PVA-Alg nanofibers.

scholarly journals Effect of Chitosan on the Properties of Electrospun Fibers From Mixed Poly(Vinyl Alcohol)/Chitosan Solutions

2017 ◽  
Vol 20 (4) ◽  
pp. 984-993 ◽  
Author(s):  
Raquel P. Gonçalves ◽  
Willian H. Ferreira ◽  
Rodrigo F. Gouvêa ◽  
Cristina T. Andrade
Keyword(s):  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Electrospun Fibers

BIODEGRADABLE BIOARTIFICIAL MATERIALS MADE BY CHITOSAN AND POLY(VINYL ALCOHOL). PART II: ENZYMATIC DEGRADABILITY AND DRUG-RELEASING ABILITY

2008 ◽  
Vol 20 (05) ◽  
pp. 321-328 ◽  
Author(s):  
Caterina Cristallini ◽  
Niccoletta Barbani ◽  
Francesca Bianchi ◽  
Davide Silvestri ◽  
Giulio D. Guerra
Keyword(s):  
Vinyl Alcohol ◽  
High Performance ◽  
Effective Diffusion ◽  
Cancer Drug ◽  
Poly Vinyl Alcohol ◽  
Effective Diffusion Coefficients ◽  
Hydrophilic Nature ◽  
Degradation Rates ◽  
Anti Cancer ◽  
Enzymatic Degradability

Bioartificial biodegradable materials were prepared mixing chitosan (CHI) and poly(vinyl alcohol) (PVA), then manufactured as films, and finally cross-linked with glutaraldehyde (GTA), both in the absence and in the presence of the edible hexa-alcohol sorbitol (SOR), as a plasticizer. The release of the components into water was tested by high performance liquid chromatography (HPLC); no release of CHI and scarce release of PVA were found. The water uptake was tested by measuring the swelling of the materials, after incubating them for 20 h in an atmosphere saturated with water vapor at 37°C. The swelling percentage increases with increasing CHI content in the blends, although it is the less hydrophilic polymer. This behavior was attributed to the difficulty of water to diffuse through the crystalline PVA structure, which is partially altered in the blends. The addition of SOR enhances the water sorption, as expected. The biodegradability of the materials was tested using the specific enzyme chitosanase, and was found to depend on the blend composition, as well as to be enhanced by the addition of SOR. The initial degradation rates were calculated; the maximum rates were found when the CHI to PVA ratio was 80:20 for all systems. The results of the enzymatic degradation generally agree with those of the swelling. The cross-linked blends were also tested as drug-delivery systems. The drugs chosen were the vitamin L-ascorbic acid (AsA) and the anti-cancer drug paclitaxel (PTX). The effective diffusion coefficients, D eff , were evaluated for the release of both the drugs from each material. Those of AsA are greater, of many powers of ten, than those of PTX, owing mainly to the hydrophilic nature of the first drug and to the hydrophobic of the second one. In conclusion, these materials seem available for biomedical use.

A novel hybrid anion exchange membrane for high performance microbial fuel cells

RSC Advances ◽  
2015 ◽  
Vol 5 (6) ◽  
pp. 4659-4663 ◽  
Author(s):  
Hu-Chun Tao ◽  
Xiao-Nan Sun ◽  
Ying Xiong
Keyword(s):  
Titanium Dioxide ◽  
Fuel Cells ◽  
Anion Exchange ◽  
Microbial Fuel Cells ◽  
Vinyl Alcohol ◽  
High Performance ◽  
Anion Exchange Membrane ◽  
Poly Vinyl Alcohol ◽  
Exchange Membrane

A novel titanium dioxide (TiO2)–quaternized poly(vinyl alcohol) (QAPVA) hybrid anion exchange membrane (T membrane) is prepared, and its feasibility for use in microbial fuel cells (MFCs) is investigated in this study.

Sign in / Sign up

Export Citation Format

Share Document