Electrodeposited spinel NiCo2O4 nanosheet arrays for glucose sensing application

RSC Advances ◽  
2015 ◽  
Vol 5 (91) ◽  
pp. 74585-74591 ◽  
Author(s):  
Kusha Kumar Naik ◽  
Suresh Kumar ◽  
Chandra Sekhar Rout

Non-enzymatic glucose sensing properties of NiCo2O4 nanosheets show linear response with respect to the change in glucose concentration varying from 5 to 65 μM and exhibit the sensitivity value of 6.69 μA μM−1 cm−2 with a LOD value of 0.38 μM.

2016 ◽  
Vol 29 (1) ◽  
pp. 213-222 ◽  
Author(s):  
Zafar Hussain Ibupoto ◽  
Aneela Tahira ◽  
Arfana Begum Mallah ◽  
Sohail Anjum Shahzad ◽  
Magnus Willander ◽  
...  

2020 ◽  
Vol 6 (4) ◽  
pp. 1909-1919 ◽  
Author(s):  
Lichchhavi Sinha ◽  
Hyunju Lee ◽  
Yoshio Ohshita ◽  
Parasharam M. Shirage

2001 ◽  
Vol 281 (4) ◽  
pp. E649-E654 ◽  
Author(s):  
Charles V. Mobbs ◽  
Lee-Ming Kow ◽  
Xue-Jun Yang

Interest in brain glucose-sensing mechanisms is motivated by two distinct neuronal responses to changes in glucose concentrations. One mechanism is global and ubiquitous in response to profound hypoglycemia, whereas the other mechanism is largely confined to specific hypothalamic neurons that respond to changes in glucose concentrations in the physiological range. Although both mechanisms use intracellular metabolism as an indicator of extracellular glucose concentration, the two mechanisms differ in key respects. Global hyperpolarization (inhibition) in response to 0 mM glucose can be reversed by pyruvate, implying that the reduction in ATP levels acting through ATP-dependent potassium (K-ATP) channels is the key metabolic signal for the global silencing in response to 0 mM glucose. In contrast, neuroendocrine hypothalamic responses in glucoresponsive and glucose-sensitive neurons (either excitation or inhibition, respectively) to physiological changes in glucose concentration appear to depend on glucokinase; neuroendocrine responses also depend on K-ATP channels, although the role of ATP itself is less clear. Lactate can substitute for glucose to produce these neuroendocrine effects, but pyruvate cannot, implying that NADH (possibly leading to anaplerotic production of malonyl-CoA) is a key metabolic signal for effects of glucose on glucoresponsive and glucose-sensitive hypothalamic neurons.


2020 ◽  
pp. 088532822097557
Author(s):  
Prem Pandey ◽  
Govind Pandey ◽  
Roger Narayan

We report on polyethylenimine (PEI)-mediated synthesis of Prussian blue nanoparticles (PBNPs) and gold nanoparticles (AuNPs); the formation of PBNP-AuNP nanohybrids with a remarkable change in Prussian blue character as a function of gold cation concentration was also considered. It was shown that PEI-protected polycrystalline PBNPs can be synthesized in an acidic medium from the precursor potassium ferricyanide [K3Fe(CN)6] at 60 °C. Since PEI also enables the controlled formation of gold nanoparticles (AuNPs) in the presence of formaldehyde under ambient conditions, nanohybrids of PBNPs and AuNPs were prepared. The formation of AuNPs was recorded over a wide range of PEI concentrations, which allowed control over polymeric cation capping of the AuNPs. PEI concentration-dependent enhancement/quenching of fluorescence/resonance Rayleigh scattering was useful for non-enzymatic detection of serum glucose levels. The resonance Rayleigh scattering intensity of PBNPs was several-fold higher than that of AuNPs and acted as a potent quencher of fluorescence. At an optimal concentration of PEI, AuNPs allowed an increase in the fluorescence signal as function of glucose concentration; the quenching ability of PB was demonstrated to be a function of the glucose concentration. This method is efficient for fast glucose sensing and offers a wider linear dynamic range, 0–10 mM, which is useful for non-enzymatic detection of serum glucose levels.


2017 ◽  
Vol 9 (28) ◽  
pp. 23894-23903 ◽  
Author(s):  
Kusha Kumar Naik ◽  
Abhijeet Gangan ◽  
Brahmananda Chakraborty ◽  
Saroj K. Nayak ◽  
Chandra Sekhar Rout

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