Selective and sensitive turn-on chemosensor for Al(iii) ions applicable in living organisms: nanomolar detection in aqueous medium

RSC Advances ◽  
2015 ◽  
Vol 5 (89) ◽  
pp. 72508-72514 ◽  
Author(s):  
Siddhartha Pal ◽  
Buddhadeb Sen ◽  
Manjira Mukherjee ◽  
Mousumi Patra ◽  
Susmita Lahiri (Ganguly) ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Cell Lines ◽  
A549 Cell ◽  
Turn On ◽  
Highly Sensitive ◽  
Nanomolar Detection ◽  
Living Organisms ◽  
Tea Extract

A new crystallographically characterized non-cytotoxic CHEF based highly sensitive Al(iii) ion selective chemosensor (L) is useful to detect the Al(iii) ions' distribution in A549 cell lines and also able to sense Al(iii) ions in tea extract.

Highly sensitive fluorescent imidazolium-based sensors for nanomolar detection of explosive picric acid in aqueous medium

2016 ◽  
Vol 229 ◽  
pp. 599-608 ◽  
Author(s):  
Santosh Kumari ◽  
Sunita Joshi ◽  
Tania C. Cordova-Sintjago ◽  
Debi D. Pant ◽  
Rajeev Sakhuja
Keyword(s):  
Aqueous Medium ◽  
Picric Acid ◽  
Highly Sensitive ◽  
Nanomolar Detection

Extraction, Chemical Composition, Antioxidant Property and In vitro Anticancer Activity of Silymarin from Silybum Marianum On Kb and A549 Cell Lines

2020 ◽  
Vol 17 ◽  
Author(s):  
Mojgan Azadpour ◽  
Mohammad Mehdi Farajollahi ◽  
Ali Mohammad Varzi ◽  
Pejman Hashemzadeh ◽  
Hossein Mahmoudvand ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
A549 Cell ◽  
Hplc Analysis ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Antioxidant Property ◽  
Silybum Marianum ◽  
Stable Free Radical

Introduction: This study aimed to evaluate the antioxidant property of silymarin (SM) extracted from the seed of Silybum marianum and its anticancer activity on KB and A549 cell lines following 24, 48, and 72 h of treatment. Methods: Ten grams of powdered S. marianum seeds were defatted using n-hexane for 6 hours and then extracted by methanol. The silymarin extracted of extraction components The extracted components of silymarin were measured by spectrophotometric assay and HPLC analysis. 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, phenol content, total flavonoid content, and total antioxidant capacity were measured to detect the antioxidant properties of SM. The anticancer activity of the SM on cell lines evaluated by MTT. Results: In HPLC analysis, more than 50% of the peaks were related to silibin A and B. SM was reducedDPPH (the stable free radical) with a 50% inhibitory concentration (IC50) of 6.56 μg/ ml in comparison with butylated hydroxyl toluene (BHT), which indicated an IC50 of ~3.9 μg/ ml.The cytotoxicity effect of SM on the cell lines was studied by MTT assay. The cytotoxicity effect of the extracted silymarin on KB and A549 cell lines was observed up to 80 and 70% at 156 and 78 µg/ml, respectively. The IC50 value of the extracted SM on KB and A549 cell lines after 24 hours of treatment was seen at 555 and 511 µg/ml, respectively. Conclusion: Due to the good antioxidant and anticancer properties of the isolated silymarin, its use as an anticancer drug is suggested.

A phenanthrene[9,10-d]imidazole-phenol-based fluorescent probe combined ESIPT and AIE for “turn-on” detection of Cu2+ with a green-emitting and improved stokes shift and its application

2021 ◽  
Author(s):  
Jiahui Du ◽  
Bing Zhao ◽  
Wei Kan ◽  
Haochun Yin ◽  
Tianshu Song ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Fluorescent Sensors ◽  
Turn On ◽  
Highly Sensitive

Development of highly sensitive and selective fluorescent sensors toward Cu2+ has gained considerable attention in view of its application of environmental and biological fields. However, the strategy of sensing by...

scholarly journals A highly sensitive and selective on–off fluorescent sensor based on a complex of polySchiff-Fe2+ for Cr(vi) detection in an aqueous medium

RSC Advances ◽  
2021 ◽  
Vol 11 (15) ◽  
pp. 8963-8969
Author(s):  
Zhiying Li ◽  
Congshu Li ◽  
Huiyun Yan
Keyword(s):  
Aqueous Medium ◽  
Fluorescent Sensor ◽  
Human Race ◽  
Safety And Health ◽  
Highly Sensitive

Designing exceptional probes to detect minute quantities of chromium(vi) is of huge importance for the safety and health of the human race.

A highly-sensitive “turn on” probe based on coumarin β-diketone for hydrazine detection in PBS and living cells

2021 ◽  
Vol 252 ◽  
pp. 119510
Author(s):  
Rui Chen ◽  
Guang-Jin Shi ◽  
Jia-Jia Wang ◽  
Hai-Feng Qin ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Living Cells ◽  
Turn On ◽  
Highly Sensitive
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