scholarly journals Composition-dependent in vitro apatite formation at mesoporous bioactive glass-surfaces quantified by solid-state NMR and powder XRD

RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86061-86071 ◽  
Author(s):  
Claudia Turdean-Ionescu ◽  
Baltzar Stevensson ◽  
Jekabs Grins ◽  
Isabel Izquierdo-Barba ◽  
Ana García ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Powder Xrd ◽  
Apatite Formation ◽  
Carbonate Apatite ◽  
Bioactive Glasses ◽  
Glass Surfaces ◽  
Mesoporous Bioactive Glass ◽  
Hydroxy Carbonate

Solid-state NMR and powder XRD are employed to quantify the ACP (amorphous calcium phosphate) and HCA (hydroxy-carbonate apatite) components grown from three mesoporous bioactive glasses with variable compositions.

scholarly journals Quantifying apatite formation and cation leaching from mesoporous bioactive glasses in vitro: a SEM, solid-state NMR and powder XRD study

2012 ◽  
Vol 22 (15) ◽  
pp. 7214 ◽  
Author(s):  
Philips N. Gunawidjaja ◽  
Isabel Izquierdo-Barba ◽  
Renny Mathew ◽  
Kjell Jansson ◽  
Ana García ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Powder Xrd ◽  
Apatite Formation ◽  
Bioactive Glasses ◽  
Cation Leaching ◽  
Xrd Study

scholarly journals Contrasting In Vitro Apatite Growth from Bioactive Glass Surfaces with that of Spontaneous Precipitation

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1690 ◽  
Author(s):  
Yang Yu ◽  
Zoltán Bacsik ◽  
Mattias Edén
Keyword(s):  
Body Fluid ◽  
Carbonate Apatite ◽  
X Ray Diffraction ◽  
Bioactive Glasses ◽  
Direct Precipitation ◽  
Living Tissues ◽  
Glass Surfaces ◽  
Supersaturated Solutions ◽  
Hydroxy Carbonate

Body-fluid-exposed bioactive glasses (BGs) integrate with living tissues due to the formation of a biomimetic surface layer of calcium hydroxy-carbonate apatite (HCA) with a close composition to bone mineral. Vast efforts have been spent to understand the mechanisms underlying in vitro apatite mineralization, as either formed by direct precipitation from supersaturated solutions, or from BG substrates in a simulated body fluid (SBF). Formally, these two scenarios are distinct and have hitherto been discussed as such. Herein, we contrast them and identify several shared features. We monitored the formation of amorphous calcium phosphate (ACP) and its crystallization into HCA from a Na 2 O–CaO–SiO 2 –P 2 O 5 glass exposed to SBF for variable periods out to 28 days. The HCA growth was assessed semi-quantitatively by Fourier transform infrared spectroscopy and powder X-ray diffraction, with the evolution of the relative apatite content for increasing SBF-exposure periods evaluated against trends in Ca and P concentrations in the accompanying solutions. This revealed a sigmoidal apatite growth behavior, well-known to apply to spontaneously precipitated apatite. The results are discussed in relation to the prevailing mechanism proposed for in vitro HCA formation from silicate-based BGs, where we highlight largely simultaneous growth processes of ACP and HCA.

Hydroxy Carbonate Apatite Formation on Particulate Bioglass In Vitro as a Function of Time

2002 ◽  
Vol 37 (11) ◽  
pp. 1165-1171 ◽  
Author(s):  
E. Kontonasaki ◽  
T. Zorba ◽  
L. Papadopoulou ◽  
E. Pavlidou ◽  
X. Chatzistavrou ◽  
...  
Keyword(s):  
Apatite Formation ◽  
Carbonate Apatite ◽  
Hydroxy Carbonate

scholarly journals Influence of strontium for calcium substitution in bioactive glasses on degradation, ion release and apatite formation

2011 ◽  
Vol 9 (70) ◽  
pp. 880-889 ◽  
Author(s):  
Yann C. Fredholm ◽  
Natalia Karpukhina ◽  
Delia S. Brauer ◽  
Julian R. Jones ◽  
Robert V. Law ◽  
...  
Keyword(s):  
Glass Network ◽  
Apatite Formation ◽  
Carbonate Apatite ◽  
Structure Property ◽  
Ion Release ◽  
Ph Change ◽  
Bioactive Glasses ◽  
Composition Structure

Bioactive glasses are able to bond to bone through the formation of hydroxy-carbonate apatite in body fluids while strontium (Sr)-releasing bioactive glasses are of interest for patients suffering from osteoporosis, as Sr was shown to increase bone formation both in vitro and in vivo . A melt-derived glass series (SiO 2 –P 2 O 5 –CaO–Na 2 O) with 0–100% of calcium (Ca) replaced by Sr on a molar base was prepared. pH change, ion release and apatite formation during immersion of glass powder in simulated body fluid and Tris buffer at 37°C over up to 8 h were investigated and showed that substituting Sr for Ca increased glass dissolution and ion release, an effect owing to an expansion of the glass network caused by the larger ionic radius of Sr ions compared with Ca. Sr release increased linearly with Sr substitution, and apatite formation was enhanced significantly in the fully Sr-substituted glass, which allowed for enhanced osteoblast attachment as well as proliferation and control of osteoblast and osteoclast activity as shown previously. Studying the composition–structure–property relationship in bioactive glasses enables us to successfully design next-generation biomaterials that combine the bone regenerative properties of bioactive glasses with the release of therapeutically active Sr ions.

In vitro Chemical Reactivity of Doped Bioactive Glasses: an Original Approach by Solid-State NMR Spectroscopy

2009 ◽  
Vol 11 (8) ◽  
pp. B98-B105 ◽  
Author(s):  
Elodie Dietrich ◽  
Hassane Oudadesse ◽  
Marie Le Floch ◽  
Bruno Bureau ◽  
Thierry Gloriant
Keyword(s):  
Solid State ◽  
Nmr Spectroscopy ◽  
Solid State Nmr ◽  
Chemical Reactivity ◽  
Bioactive Glasses ◽  
Solid State Nmr Spectroscopy ◽  
Original Approach

scholarly journals Confirmation by solid-state NMR spectroscopy of a strong complex phenol-dietary fiber with retention of antioxidant activity in vitro

2020 ◽  
Vol 102 ◽  
pp. 105584 ◽  
Author(s):  
Alejandra Bermúdez-Oria ◽  
Guillermo Rodríguez-Gutiérrez ◽  
África Fernández-Prior ◽  
Heike Knicker ◽  
Juan Fernández-Bolaños
Keyword(s):  
Antioxidant Activity ◽  
Solid State ◽  
Nmr Spectroscopy ◽  
Dietary Fiber ◽  
Solid State Nmr ◽  
Solid State Nmr Spectroscopy

Quantitative phase analyses of biomedical pyrophosphate-bearing monetite and brushite cements by solid-state NMR and powder XRD

2020 ◽  
Vol 46 (8) ◽  
pp. 11000-11012
Author(s):  
Hua Guo ◽  
Michael Pujari-Palmer ◽  
Yang Yu ◽  
Baltzar Stevensson ◽  
Håkan Engqvist ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Powder Xrd ◽  
Quantitative Phase
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