Stereoselective synthesis of 3-amino-2-oxindoles from isatin imines: new scaffolds for bioactivity evaluation

RSC Advances ◽  
2015 ◽  
Vol 5 (65) ◽  
pp. 52481-52496 ◽  
Author(s):  
Jasneet Kaur ◽  
Swapandeep Singh Chimni ◽  
Suhel Mahajan ◽  
Akshay Kumar
Keyword(s):  
Natural Products ◽  
Stereoselective Synthesis ◽  
Core Structure ◽  
Drug Candidates ◽  
The Core

3-Substituted-3-aminooxindole motifs constitute the core structure of a number of natural products and drug candidates.

Stereoselective synthesis of an eleganine A core

2020 ◽  
Vol 18 (24) ◽  
pp. 4566-4568
Author(s):  
Gints Smits ◽  
Ronalds Zemribo
Keyword(s):  
Stereoselective Synthesis ◽  
Core Structure ◽  
The Core ◽  
First Time

The core structure of eleganine A – a cytotoxic indole monoterpene alkaloid – was accessed for the first time.

scholarly journals Recent Advances in Organocatalyzed Asymmetric Synthesis of Benzopyran and Benzodihydropyran (Chromane) Nuclei

Symmetry ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1510
Author(s):  
Renato Dalpozzo ◽  
Raffaella Mancuso
Keyword(s):  
Natural Products ◽  
Asymmetric Synthesis ◽  
Organic Synthesis ◽  
Building Blocks ◽  
Core Structure ◽  
The Core ◽  
Recent Advances ◽  
Set Up

Benzopyran and benzodihydropyran (chromane) nuclei are the core structure of many natural products, in particular flavonoids. Many compounds possessing this structure are nutraceuticals, pharmaceutical nutrients. Therefore, benzopyran and chromane scaffolds are important building blocks in organic synthesis and many efforts have been made to set up efficient methods for their synthesis. In particular, asymmetric methods are of great importance, being natural products, and generally chiral substances. This review aims to cover literature in the range 2017–first half of 2019.

scholarly journals Efficient synthesis of bis(indolyl)methanes by the alkylation of indoles with alcohols using heterogeneous CuFe2O4 catalyst

2021 ◽  
Vol 10 (3) ◽  
pp. 98-104
Author(s):  
Tuan Ha Minh ◽  
Yen Bui Hoang ◽  
Khanh Nguyen Ngoc ◽  
Thuan Ngo Thi ◽  
Hung Tran Quang ◽  
...  
Keyword(s):  
Natural Products ◽  
Catalytic Activity ◽  
Heterogeneous Catalyst ◽  
Core Structure ◽  
Efficient Synthesis ◽  
Active Compounds ◽  
The Core ◽  
Highly Efficient ◽  
Pharmacologically Active ◽  
Pharmacologically Active Compounds

Bis(3-indolyl)methanes (BIM) are highly valuable and appear in the core structure of many natural products and pharmacologically active compounds (anticancer, anti-inflammatory, antiobesity, antimetastatic, antimicrobial, etc.). Herein, we have disclosed an air stable and highly efficient CuFe2O4 heterogeneous catalyst for alkylation of indoles with alcohols to give bis(3-indolyl)methanes in very good yields. The CuFe2O4 catalyst has been found to be magnetically recycled at least five times without losing significant catalytic activity.

Recent advances in the catalytic synthesis of 3-aminooxindoles: an update

2020 ◽  
Vol 18 (25) ◽  
pp. 4692-4708 ◽  
Author(s):  
Jasneet Kaur ◽  
Banni Preet Kaur ◽  
Swapandeep Singh Chimni
Keyword(s):  
Natural Products ◽  
Catalytic Synthesis ◽  
Biologically Active Compounds ◽  
Core Structure ◽  
Biologically Active ◽  
Active Compounds ◽  
The Core ◽  
Recent Advances

3-Substituted-3-aminooxindoles are versatile scaffolds and these motifs constitute the core structure of number of natural products and biologically active compounds.

ChemInform Abstract: Stereoselective Synthesis of the Core Structure of the Nephritogenoside Glycopeptide.

ChemInform ◽  
2010 ◽  
Vol 28 (50) ◽  
pp. no-no
Author(s):  
H. ZHANG ◽  
Y. WANG ◽  
R. THUERMER ◽  
M. MEISENBACH ◽  
W. VOELTER
Keyword(s):  
Stereoselective Synthesis ◽  
Core Structure ◽  
The Core

Stereoselective Synthesis of the Core Structure of the Nephritogenoside Glycopeptide

1997 ◽  
Vol 1997 (9) ◽  
pp. 1871-1876 ◽  
Author(s):  
Hong Zhang ◽  
Yali Wang ◽  
René Thürmer ◽  
Mark Meisenbach ◽  
Wolfgang Voelter
Keyword(s):  
Stereoselective Synthesis ◽  
Core Structure ◽  
The Core
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