Role of novel silicon nanoparticles in luminescence detection of a family of antibiotics

RSC Advances ◽  
2015 ◽  
Vol 5 (35) ◽  
pp. 27458-27463 ◽  
Author(s):  
Jintai Lin ◽  
Qianming Wang
Keyword(s):  
Silicon Nanoparticles ◽  
Photophysical Properties ◽  
Practical Application ◽  
Design Synthesis ◽  
Luminescence Detection ◽  
Quantum Size ◽  
Fluorescent Silicon Nanoparticles

The design, synthesis, photophysical properties and practical application of fluorescent silicon nanoparticles (SiNPs) of a quantum-size (∼3 nm) have been studied.

scholarly journals The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 246
Author(s):  
Patrick Severin Sfragano ◽  
Giulia Moro ◽  
Federico Polo ◽  
Ilaria Palchetti
Keyword(s):  
Functional Groups ◽  
Synthetic Peptides ◽  
Clinical Diagnostics ◽  
Electrochemical Biosensors ◽  
Practical Application ◽  
Design And Development ◽  
Electrode Surfaces ◽  
Electrochemical Transducers ◽  
Target Analyte

Peptides represent a promising class of biorecognition elements that can be coupled to electrochemical transducers. The benefits lie mainly in their stability and selectivity toward a target analyte. Furthermore, they can be synthesized rather easily and modified with specific functional groups, thus making them suitable for the development of novel architectures for biosensing platforms, as well as alternative labelling tools. Peptides have also been proposed as antibiofouling agents. Indeed, biofouling caused by the accumulation of biomolecules on electrode surfaces is one of the major issues and challenges to be addressed in the practical application of electrochemical biosensors. In this review, we summarise trends from the last three years in the design and development of electrochemical biosensors using synthetic peptides. The different roles of peptides in the design of electrochemical biosensors are described. The main procedures of selection and synthesis are discussed. Selected applications in clinical diagnostics are also described.

scholarly journals Design, synthesis, molecular docking, and in vitro α-glucosidase inhibitory activities of novel 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines against yeast and rat α-glucosidase

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Fariba Peytam ◽  
Ghazaleh Takalloobanafshi ◽  
Toktam Saadattalab ◽  
Maryam Norouzbahari ◽  
Zahra Emamgholipour ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Study ◽  
Rat Small Intestine ◽  
Molecular Docking Study ◽  
Design Synthesis ◽  
Mild Conditions ◽  
Glucosidase Inhibitors ◽  
Inhibitory Activities

AbstractIn an attempt to find novel, potent α-glucosidase inhibitors, a library of poly-substituted 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines 3a–ag have been synthesized through heating a mixture of 2-aminobenzimidazoles 1 and α-azidochalcone 2 under the mild conditions. This efficient, facile protocol has been resulted into the desirable compounds with a wide substrate scope in good to excellent yields. Afterwards, their inhibitory activities against yeast α-glucosidase enzyme were investigated. Showing IC50 values ranging from 16.4 ± 0.36 µM to 297.0 ± 1.2 µM confirmed their excellent potency to inhibit α-glucosidase which encouraged us to perform further studies on α-glucosidase enzymes obtained from rat as a mammal source. Among various synthesized 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines, compound 3k exhibited the highest potency against both Saccharomyces cerevisiae α-glucosidase (IC50 = 16.4 ± 0.36 μM) and rat small intestine α-glucosidase (IC50 = 45.0 ± 8.2 μM). Moreover, the role of amine moiety on the observed activity was studied through substituting with chlorine and hydrogen resulted into a considerable deterioration on the inhibitory activity. Kinetic study and molecular docking study have confirmed the in-vitro results.

A dual-emission ratiometric fluorescent nanoprobe based on silicon nanoparticles and carbon dots for efficient detection of Cu(II)

CrystEngComm ◽  
2021 ◽  
Author(s):  
Huiyuan Kou ◽  
Shujie Pang ◽  
Boyu Yang ◽  
Mao Wang ◽  
Juan Ding ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Silicon Nanoparticles ◽  
Dual Emission ◽  
Emission Properties ◽  
Fluorescent Nanoprobe ◽  
Fluorescent Silicon Nanoparticles ◽  
Efficient Detection ◽  
New Type

In this work, a new type of ratiometric fluorescent nanoprobe with dual-emission properties is designed and constructed. The dual-emission nanoprobe is prepared from fluorescent silicon nanoparticles (Si NPs) and carbon...

Exploration of synthesizing fluorescent silicon nanoparticles and label-free detection of sulfadiazine sodium

Talanta ◽  
2020 ◽  
Vol 220 ◽  
pp. 121410
Author(s):  
Yunfeng Bai ◽  
Qian Su ◽  
Jimei Xiao ◽  
Feng Feng ◽  
Xiaoming Yang
Keyword(s):  
Silicon Nanoparticles ◽  
Label Free ◽  
Fluorescent Silicon Nanoparticles ◽  
Label Free Detection

Ratiometric target-triggered fluorescent silicon nanoparticles probe for quantitative visualization of tyrosinase activity

Talanta ◽  
2019 ◽  
Vol 197 ◽  
pp. 113-121 ◽  
Author(s):  
Yu-Zhu Ding ◽  
Wei-Feng Wang ◽  
Tian Chai ◽  
Yin Qiang ◽  
Yan-Ping Shi ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Tyrosinase Activity ◽  
Fluorescent Silicon Nanoparticles ◽  
Quantitative Visualization

Design, synthesis and photophysical properties of A-D-A-D-A small molecules for photovoltaic application

2015 ◽  
Vol 121 ◽  
pp. 99-108 ◽  
Author(s):  
Weibo Yan ◽  
Qian Zhang ◽  
Qingsong Qin ◽  
Senyun Ye ◽  
Yuanwei Lin ◽  
...  
Keyword(s):  
Small Molecules ◽  
Photophysical Properties ◽  
Design Synthesis ◽  
Photovoltaic Application

Photophysical properties of luminescent silicon nanoparticles surface-modified with organic molecules via hydrosilylation

2016 ◽  
Vol 15 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Mari Miyano ◽  
Yuichi Kitagawa ◽  
Satoshi Wada ◽  
Akira Kawashima ◽  
Ayako Nakajima ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Organic Molecules ◽  
Photophysical Properties ◽  
Electron System ◽  
Surface Modified

Luminescent silicon nanoparticles with a π-electron system are expected to be an important factor for creating strongly luminous silicon nanoparticles.

scholarly journals Complex interactions in legume/cereal intercropping system: role of root exudates in root-to-root communication

2017 ◽  
Author(s):  
Yinshan Jiao ◽  
Entao Wang ◽  
Wenfeng Chen ◽  
Donald L. Smith
Keyword(s):  
Nitrogen Fixation ◽  
Root Exudates ◽  
Faba Bean ◽  
The Novel ◽  
Practical Application ◽  
Corn Root ◽  
Complex Interactions ◽  
Root Interactions ◽  
Ecological Principles

Dear Editor,Legume/cereal intercropping systems have been regarded as the practical application of basic ecological principles such as diversity, competition and facilitation. In a recent PNAS paper, Li et al. (1) describe the novel finding that maize exudates promote faba bean nodulation and nitrogen fixation by upregulating genes involved in (iso)flavonoids synthesis (chalcone–flavanone isomerase) within faba bean, resulting in production of more genistein, a legume-to-rhizobia signal during establishment of the faba bean N2–fixing symbiosis. Although we salute the authors’ methodological efforts, there is another mechanism that could be responsible for the effect of corn root exudates on faba been nitrogen fixation observed in this article (1). The authors may misunderstand their data and the signalling role of maize exudates, thus got a defective model for the root interactions between faba bean and maize.

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