Magnetic Prussian blue nanoparticles for combined enzyme-responsive drug release and photothermal therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (36) ◽  
pp. 28401-28409 ◽  
Author(s):  
Peng Xue ◽  
Jingnan Bao ◽  
Yafeng Wu ◽  
Yilei Zhang ◽  
Yuejun Kang
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Prussian Blue Nanoparticles

Multifunctional magnetic nanoparticles based on Fe3O4 nanocore and Prussian blue nanoshell for combined enzyme-responsive drug release and photothermal therapy.

Glypican-3 antibody functionalized Prussian blue nanoparticles for targeted MR imaging and photothermal therapy of hepatocellular carcinoma

2014 ◽  
Vol 2 (23) ◽  
pp. 3686-3696 ◽  
Author(s):  
Zhenglin Li ◽  
Yongyi Zeng ◽  
Da Zhang ◽  
Ming Wu ◽  
Lingjie Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mr Imaging ◽  
Minimally Invasive ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Minimally Invasive Technique ◽  
Invasive Technique ◽  
Prussian Blue Nanoparticles ◽  
Mri Guided

MRI-guided photothermal therapy is becoming a more widely accepted minimally invasive technique.

A chloroquine-loaded Prussian blue platform with controllable autophagy inhibition for enhanced photothermal therapy

2018 ◽  
Vol 6 (37) ◽  
pp. 5854-5859 ◽  
Author(s):  
Yan Ma ◽  
Huajian Chen ◽  
Baimei Hao ◽  
Junhong Zhou ◽  
Gang He ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Prussian Blue Nanoparticles ◽  
Delivery Platform ◽  
Autophagy Inhibition

A controllable CQ delivery platform consisting of hollow mesoporous Prussian blue nanoparticles and phase changing material was developed here to realize tumor specific autophagy inhibition for enhanced PTT.

scholarly journals Mn doped Prussian blue nanoparticles for T1/T2 MR imaging, PA imaging and Fenton reaction enhanced mild temperature photothermal therapy of tumor

2022 ◽  
Vol 20 (1) ◽  
Author(s):  
Quan Tao ◽  
Genghan He ◽  
Sheng Ye ◽  
Di Zhang ◽  
Zhide Zhang ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Fenton Reaction ◽  
Infrared Range ◽  
Prussian Blue Nanoparticles ◽  
Mild Temperature ◽  
Mn Doped

Abstract Background Combining the multimodal imaging and synergistic treatment in one platform can enhance the therapeutic efficacy and diagnosis accuracy. Results In this contribution, innovative Mn-doped Prussian blue nanoparticles (MnPB NPs) were prepared via microemulsion method. MnPB NPs demonstrated excellent T1 and T2 weighted magnetic resonance imaging (MRI) enhancement in vitro and in vivo. The robust absorbance in the near infrared range of MnPB NPs provides high antitumor efficacy for photothermal therapy (PTT) and photoacoustics imaging property. Moreover, with the doping of Mn, MnPB NPs exhibited excellent Fenton reaction activity for chemodynamic therapy (CDT). The favorable trimodal imaging and Fenton reaction enhanced mild temperature photothermal therapy in vitro and in vivo were further confirmed that MnPB NPs have significant positive effectiveness for integration of diagnosis and treatment tumor. Conclusions Overall, this Mn doped Prussian blue nanoplatform with multimodal imaging and chemodynamic/mild temperature photothermal co-therapy provides a reliable tool for tumor treatment. Graphical Abstract

Prussian blue nanoparticles for laser-induced photothermal therapy of tumors

RSC Advances ◽  
2014 ◽  
Vol 4 (56) ◽  
pp. 29729 ◽  
Author(s):  
Hilary A. Hoffman ◽  
Lina Chakrabarti ◽  
Matthieu F. Dumont ◽  
Anthony D. Sandler ◽  
Rohan Fernandes
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Prussian Blue Nanoparticles
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